Understanding Nootropics Side Effects: Risks to Consider

September 20, 2024

Nootropics, also known as cognitive enhancers or smart drugs, are substances that aim to improve memory, mental alertness, and concentration. The manufacturers of the supplements and drugs always include a section on potential nootropics side effects in their official instructions. In some cases, these side effects are minimal, while in others, they may be more extensive, largely depending on how well the specific nootropic has been studied. Beyond these official reports, there are many anecdotal side effects shared by users, which often reflect individual reactions to the drug or its active ingredients.

It’s important to approach these personal accounts with caution though, as the link between a specific nootropic and a side effect isn’t always clear. Many factors, such as pre-existing conditions or reactions to other substances, can contribute to symptoms that are mistakenly attributed to the nootropic. The anecdotal side effects shared in this article reflect personal experiences, which may not necessarily indicate a direct cause-and-effect relationship with the drug itself.

Common Side Effects of Nootropics

Common nootropics side effects reported by producers are based on data from clinical trials and post-market monitoring. These trials track adverse reactions in participants and, along with reports from healthcare professionals, form the official list of side effects. This information is included in the drug’s labeling to inform users of potential risks, with the most frequent side effects often being mild.

Here’s a list of the main categories of side effects for nootropics:

Headaches, Dizziness, Cognitive fog or confusion, Seizures (in rare cases)

Anxiety, Mood swings, Irritability, Insomnia, Depression

Nausea, Stomach pain, Diarrhea, Constipation, Loss of appetite

Increased heart rate, High blood pressure, Heart palpitations

Fatigue, Weight gain or loss, Hormonal imbalances

Skin rash, Itching, Swelling, Breathing difficulties (in severe cases)

Tolerance buildup, Physical or psychological dependence, Withdrawal symptoms (e.g., irritability, fatigue)

Blurred vision, Sensitivity to light, Auditory disturbances (e.g., ringing in ears)

High blood pressure (hypertension), Low blood pressure (hypotension), Fluctuations in blood pressure, Dizziness or lightheadedness due to pressure changes

This list covers a broad range of common and less frequent side effects experienced with nootropics.

User-Reported (Anecdotal) Side Effects from Reddit

Anecdotal side effects are personal reports of adverse reactions that users often link to nootropic use. While these experiences offer valuable insights, they can be influenced by various factors unrelated to the nootropic, such as pre-existing health issues or lifestyle changes. Understanding these personal accounts can be informative and help individuals be more aware of potential issues. However, it’s crucial to remember that such effects can be highly individual, and what one person experiences may not apply to everyone. Below, we provide a list of such personal anecdotal side effects, organized by drug.

Cerebrolysin: abscesses, exhaustion, fever

Phenibut: dry and peeling skin on fingers, vision deterioration

Semax: throat pain / painful swallowing, hair loss

Stresam: skin bumps

We plan to update this article with additional examples of personal side effect experiences as we learn about them, including from the clients of CosmicNootropic. By incorporating a broader range of anecdotal reports, we aim to provide a more comprehensive view of the potential variations in how individuals may react to nootropics. This ongoing update will help ensure that readers have access to the latest and most relevant information when considering these supplements.

Other Points to Consider

Placebo effect

Nootropics can vary significantly in their effects, which differ from person to person. While some individuals may experience genuine biochemical changes due to a particular preparation, others might find it to be merely a placebo. This variability often hinges on one’s biochemical makeup and mental state.

Is this problematic? Is the placebo effect merely a waste of time and money? In fact, placebo effects can be as legitimate as non-placebo effects. However, in some cases it is generally advisable to opt for preparations with long-term effects rooted in biochemical action.

Psychological Problems

While nootropics can be particularly beneficial for individuals with psychiatric conditions or cognitive impairments, there is a downside. Those with a history of psychological issues may face an increased risk of relapse or developing new problems. Therefore, it is crucial to exercise caution when selecting nootropic preparations. Consulting a specialist before starting any medication is always advisable.

Social Problems

Social problems often stem from psychological issues, as the mind continually interacts with its environment. Mental challenges can disrupt various activities. However, when chosen wisely, nootropics can help address many social difficulties. Additionally, once you discover effective coping strategies, you may continue to benefit from them even after discontinuing nootropic use, as the memory of successful experiences tends to endure and can be more effective than the nootropics themselves.

Conclusion

While nootropics are marketed as having minimal side effects, both official reports and personal user experiences reveal a variety of potential issues. It’s important to consider both sources of information, recognizing that individual responses can differ. Always consult a healthcare professional before starting any new supplement to ensure it’s appropriate for your specific health needs.

You can find more information about the side effects in the Instructions section.

Bibliography

  1. Nootropics as Cognitive Enhancers: Types, Dosage and Side Effects of Smart Drugs. Matěj Malík and Pavel Tlustoš
  2. Towards better brain management: nootropics. Ruchi Malik, Abhijeet Sangwan, Ruchika Saihgal, Dharam Paul Jindal, Poonam Piplani
  3. Benefits and Harms of ‘Smart Drugs’ (Nootropics) in Healthy Individuals. Fabrizio Schifano, Valeria Catalani, Safia Sharif, Flavia Napoletano, John Martin Corkery, Davide Arillotta, Suzanne Fergus, Alessandro Vento, Amira Guirguis

Legal Disclaimer

All statements on this page are for informational purposes only and have not been evaluated or approved by the US FDA.
Products mentioned on this page are not intended to diagnose, treat, cure, or prevent any disease. See more

  1. Ruth 14/10/2024 am31 07:52 AM Reply

    I have been having success with using Phenibut for my insomnia l know how withdrawal insomnia works. I clear my system out every 4th night . I just don’t sleep that night and then take them again for 3 nights. . Other than the withdrawal insomnia every 4th night, I have no other ill affects

    • CosmicNootropic 23/10/2024 am31 10:23 AM Reply

      Hi Ruth! Thank you for sharing your experience! We’re glad to hear that you have been having success with using Phenibut for your insomnia.
      Please note that the effects of most nootropics can vary for different people. It strongly depends on personal conditions, so we always recommend consulting a doctor before taking any medication.

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