One of the Best Books about Nootropics – Translated into English!

There are many books about nootropics on Amazon. But very few of them are written by doctors or authors with formal science credentials. CosmicNootropic found a book about nootropics and supplements by a prominent Soviet scientist and doctor Edward Arushanian who is a genuine nootropics expert.

The book was published in 2016. It is called “Medical Improvement of the Cognitive Brain Function”. It is written mainly for students of medical universities and has information regarding various aspects of cognitive brain function.  

Following the initiative of translating this book into English, last year we launched the crowd-funding campaign via GoFundMe because we wanted to make it available to read for all the nootropic enthusiasts like ourselves. In April 2022 the crowd-funding was completed 🥳 With your help we have raised 1,761$ out of 2,500$ and the rest was added by CosmicNootropic.

And now we have the first two chapters from the translation agency 👇🏼 There are yet another two ones to come. But we do not want to make you wait any longer. SO HERE THE TRANSLATION OF CHAPTERS 1 & 2 👇🏼

To leave a comment or indulge in the discussion please go to our post on Reddit  


About the Author

Professor Arushanian. Books about nootropics
Prof. Edward Arushanian

Edward Arushanian is the Doctor of Medicine, professor, and the current Head of the Pharmacology faculty of the Stavropol State Medical University (Russia) and an acting member of the New York Academy of Sciences (since 1995). Dr. Arushanian was granted the Honored Scientist of Russia in 1995 as well as a number of other academic Soviet and Russian awards. His professional interest lies in neuropharmacology and neurophysiology. Dr. Arushanian is the author of 855 scientific papers including 27 monographs and about 150 foreign articles, some of them can be found in PubMed. He was the mentor of 9 doctoral theses. 

Dr. Edward Arushanian was born in 1934 in Vladivostok (Russia) and started his scientific path at the age of 19 at the Pavlov university in Saint-Petersburg. In his younger years, Edward Arushanian worked under the mentorship of Dr. Vladimir Zakusov, one of the most prominent medical academicians of the USSR who was the Head of the Zakusov Institute of Pharmacology where Semax, Selank, Noopept, and many other medications were discovered. 

Edward Arushanian during his 3rd year of university (1954)

After graduating with honors from the Pavlov university Edward Arushanian started his scientific career in a position of medical assistant at the Chita State Academy of Medicine (Chita, Russia) where he rose to the Head of the faculty of Pharmacology. In 1964 Dr. Arushanian organized a micro-neurophysiological laboratory which was the first in Siberia at that time. Over 13 years of work in Chita Dr. Arushanian developed a strong scientific and professoriate team, his faculty carried out research devoted to the study of physiological and pharmacological features of the basal ganglia of telencephalon with the assistance of colleagues from cross-disciplinary faculties: psychiatrist, neuropathologist, etc.

Together they developed the concept of antipsychotic effect of neuroleptics and new methods of treating Parkinsonism and epilepsy. The materials were presented in international congresses in San-Francisco (1972), Helsinki (1975), and in Paris (1978) at the IV International Congress of Pharmacologists where Dr. Arushanian was the main speaker.

Arushanian Nootropics Book
The lecture of Dr. Arushanian

In 1983 Dr. Arushanian left his high post at Chita university at the summit of his fame and regard and moved to the city of Stavropol to look after his elderly parents. There he was assigned the Head of the Pharmacology faculty of the Stavropol State Medical University.

He had to start over and re-create the faculty: the team, the equipment, the research. Under the leadership of Professor Arushanian, the department launched a set of works to elaborate the unified scientific program “Chronopharmacology“. The task of the research team was to study the dependence of the pharmacological effect on the state of biological rhythms and the effect of drugs on the oscillatory processes in the body. 

For the first time, the hypothesis of the chronopharmacological effect of antidepressants was substantiated in experimental conditions. A new point of view on the origin of the anti-anxiety action of anxiolytic drugs was suggested. Chronobiological characteristics of the action of psychomotor stimulants like caffeine and amphetamines were presented.

A lot of research was devoted to elucidating the contribution of the visual analyzer to the psychostimulant effect and the possibility of a direct pharmacological intervention in the function of the photosensitive apparatus of the retina was postulated. The obtained results were included in a complex of works published after 2000.

Dr. Arushanian described his relations with science in the following way: “Since my student years, Science has become one of the most exciting pursuits of my life. There is always a place for discovery if you avoid the tick-box approach. A creative insight may lead to big conclusions that give you joy, equal to the joy of creativity in art. This is what prompts me to do Science outside the box.”

Arushanian Nootropics and his colleagues
The scientific staff of the Pharmacology faculty of the Stavropol State Medical University (2012)

What do his students say about their Professor?

Dr. Arushanian has respect for the younger. His willingness to listen and delve into go hand in hand with high demands without any discounts for youth or inexperience. Everyone is given the right to think and work on their own, but everyone shall bear full responsibility for their actions. 

K. S. Elbekyan, Doctor of Biology, Head of the Department of General and Biological Chemistry of the Stavropol State Medical University, Professor

When I had to make the choice of specialization, I gave preference to pharmacology without any hesitation, largely thanks to the personality of Dr. Arushanian.

K.B. Ovanesov, Doctor of Medical Sciences, Professor of the Department of Pharmacology of the Stavropol State Medical University

I am immensely glad that my dear Teacher to whom I owe everything – my interest in science, my successful professional career, my understanding of life – not only continues to work being the country’s leading specialist in the field of chronoIt was important for me to feel his support and paternal guidance during my student years. I felt it even when I moved abroad. I continued and developed his scientific ideas on the other side of the earth. 

Orhiy Paul Botvev, professor at the University of Texas (USA), graduate of the Stavropol State Medical University

Heading of the Book about Nootropics

The heading of the Nootropics Book

INTRODUCTION

CHAPTER I. SOME PHYSIOLOGICAL ASPECTS OF COGNITIVE PROCESSES

  1. What are the main mechanisms of memory?
  2. What brain structures participate in the organization of cognition?
  3. How does the visual system contribute to the brain’s cognitive activity?
  4. Does cognition depend on the time factor?
  5. What are the aspects of the normal cerebral blood flow as a necessary condition for the optimal cognitive function?
  6. Can hormones be regarded as enhancers of cognitive processes?  
  7. Does the epiphyseal hormone melatonin have an effect on memory processes?
  8. To what extent can the immune system be interested in the organization of cognitive processes?

CHAPTER II. PATHOPHYSIOLOGICAL AND PATHOCHEMICAL ASPECTS OF COGNITIVE DISORDERS

  1. What are the special features of the origin and development of amnestic disorders in people?
  2. How does the disruption of the functionality of the corpus striatum affect cognition?
  3. Is cognitive pathology connected with vision deterioration?
  4. Does cognitive pathology depend on chronobiological disorders?
  5. What is the genesis of cognitive impairments and of the mechanism of injury of neurons in the brain blood flow dysfunction?
  6. How and by what does cerebral hypoxia affect cognitive processes?
  7. What is the role of free radical processes in the organic pathology of the brain?
  8. What is the role of nitric oxide in the normal and pathologically deteriorated cognition?
  9. How does the lack of cholinergic mechanisms in the brain affect cognitive dysfunction?
  10. What are the consequences of an excessive increase in the activity of excitatory amino acids for the brain function?
  11. Can dysfunctions in the immune system affect cognition?
  12. What is apoptosis and what are the consequences of its exacerbation for cognition?

CHAPTER III. MECHANISMS OF NOOTROPIC EFFECT

  1. How to reveal the nootropic activity of medications experimentally and clinically?
  2. What is the impact of the neurochemical mechanisms of the hippocampus on the nootropic effect?
  3. How do nootropics influence vision?
  4. Do nootropics have a chronotropic action? And if they do, is it connected with a specific action of substances?
  5. Do nootropics ensure the anti-ischemic effect and to what extent does their specific action correlate with brain vasodilation?
  6. What is the impact of the anti-hypoxic activity on the nootropic effect?
  7. Does the nootropic activity depend on the antioxidant properties of medical substances?
  8. Is the stimulation of the central cholinergic transmission a mandatory component of the nootropic action?
  9. Do the dopaminergic mechanisms of the corpus striatum take part in the specific activity of nootropics?
  10. What is the nature of GABA-eric compounds as nootropics?
  11. To what extent are the ovarium estrogenic hormones responsible for cognition?
  12. Can the epiphyseal hormone melatonin be considered as a potential nootropic?
  13. What is the nature of neuropeptides as nootropics?
  14. Can we use the immunological path to treat cognitive disturbances including the treatment with nootropics?
  15. Is the inhibition of apoptosis part of the specific activity of nootropics?
  16. What is the essence of the whole range of nootropic inner mechanisms of action?

CHAPTER IV. PHARMACOLOGY OF NOOTROPICS

  1. How does the classification of modern nootropics look like?
  2. What are the general pharmacological properties of nootropics?
  3. Where the specific psychotropic activity of nootropics is applied?
  4. What is the application of non-specific psychotropic and non-psychotropic properties of nootropics in the clinic?
  5. What are the adverse reactions of the treatment with nootropics?

CONCLUSION

LIST OF ABBREVIATIONS

BIBLIOGRAPHY


Stay tuned! Stay healthy! 

CosmicNootropic 🚀

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