BIOTREDIN (L-threonine + Vitamin B6)


A single tablet contains 0.1 g threonine and 0.005 g of pyridoxine hydrochloride + inactive ingredients (citric acid, povidone and magnesium stearate).

Pharmacodynamics and Pharmacokinetics

After placing the tablet under the tongue, the body absorbs L-threonine and pyridoxine into the blood. Threonine is then broken down into glycine and acetaldehyde (pyridoxine works as a catalyser). Acetic acid and glycine stimulate the synthesis of adenosine triphosphate (ATP) in cells, redox, and cellular respiration.

Administration and dose

Tablets are to be crushed or administered sublingually.

To increase productivity and concentration: take three tablets a day for one week to 10 days. Patients may repeat this course of treatment four times a year.

For treating alcoholism: 1-3 tablets, to be taken three times a day over the course of five days. Patients may repeat the course of treatment ten times a year.

For withdrawal syndrome: 3-4 tablets, to be taken in the first 24 hours. After this, two tablets taken three times a day. The course of treatment should last 10-28 days.

According to the instructions for Biotredin, it is most effective when taken along with glycine.

Doctors may suggest to administer three tablets on an empty stomach to detect and treat latent cravings for alcohol during remission. Acute side effects and facial flushing indicate that alcohol cravings are present. This calls for a course of Biotredin and glycine. Glycine is to be taken 15 minutes before administering 0.1 g of Biotredin under the tongue.

Biotredin is a nootropic medication which improves metabolism and boosts cellular energy. The drug is comprised of L-threonine and pyridoxine hydrochloride (vitamin B6). Together, threonine and vitamin B6 interact to form:

  • The amino acid glycine
  • Acetaldehyde
  • The resulting substance promotes active stimulation of inhibitory processes, oxidation-reduction, and supports respiratory function, and synthesis of adenosine triphosphate in the cells. This medication was developed by Russian researchers at the ‘Biotiki’ pharmaceutical company.

    Primary indications:

  • Concentration problems and poor task performance in children and young adults;
  • Treating various stages of alcoholism;
  • Managing symptoms of withdrawal syndrome in patients with alcohol dependency;
  • Irritability and depression;
  • Treatment during remission.
  • Biotredin gained wide exposure primarily as an effective and safe drug for treating alcohol dependency. Doctors believe the main advantage of Biotredin over other similar drugs is that it is fast acting and can be used to treat children of any age.

    The unique combination of threonine and pyridoxine has a synergetic effecton the improvement of the brain function.

    Although Biotredin is capable of treating psychological strain and stress, it is not a sedative (it doesn’t suppress the central nervous system). Therefore, it does not cause dependency or lethargy.

    L-threonine and vitamin B6 are natural substances for living organisms.

    L-threonine is а structural element of the central nervous system and is an essential amino acid the human body cannot synthesize on its own.

    L-threonine has the following biological effects on the body:

  • It activates metabolism in tissue;
  • It strengthens intellectual qualities;
  • It increases general productivity;
  • It alleviates psycho-emotional stress;
  • It works to treat alcoholism;
  • It diminishes symptoms of withdrawal syndrome.

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