NOBEN ® [Idebenon]

Dosage and administration

The normal dose is 60 - 90 mg 2-3 times per day. The duration of a course of treatment can vary from 1 to 2 months. Depending on the symptoms, the course can be taken 2-3 times per year.

Side effects

Side effects include allergic reactions (itchy skin), headaches, difficulty falling asleep and dyspepsia.


An increase in potential side effects.

Note: Anecdotal reports in Russia show that Noben is pretty effective as a nootropic agent but the effect may vary depending on the individual's brain chemistry.

Country of Manufacture: Russia

Already in February 2007, Idebenon has been described as an orphan drug for the treatment of Leber's hereditary optic neuropathy (LHON). In 2016, the European commission  approved the drug for the treatment of this condition. In the US, the drug has been given "fast track" by FDA as a potential treatment for Duchenne Muscular Dystrophy (DMD

In the same time, in Russia Idebenon is being used for treatment of MELAS (mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes), Leber's hereditary optic neuropathy (LHON), Duchenne muscular dystrophy (Catena) and some other conditions. 

A number of researchers recommend Idebenon therapy for the treatment of various neurological disorders due its nootropic pharmacology.

Indeed, as a structural analogue of CoQ10, the drug was shown to improve cerebral blood flow and oxygen delivery to human brain. It improves metabolic processes; in particular, it increases synthesis of glucose and adenosine triphosphate (ATP) and supports lactate elimination. Also, Idebenon slows down the process of lipid peroxidation and protects membranes of neurones and mitochondria from damage.   

The drug is produced by Binnopharm in a large pharmaceutical factory located in the city of Zelenograd.

Type: Nootropics