Dosage and administrationFor the purpose of increasing tolerance to mental and physical overload, you should take 250 mg of Mildronate 2 - 4 times per day. Before and during the athletic events, athletes should take up to 500-1000 mg prior to workouts, preferably in the morning. The duration of a course is between 14 and 21 day.
Mildronate is, in general, well-tolerated and side effects are rare. They may include high blood pressure, agitation and allergy reactions.
Cases of overdose have not been reported.
Country of Manufacture: Latvia
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Back in 1975, the creator of Mildronate (also known as Meldonium), professor Kalvins, was studying all body chemicals that can be deplenished during endurance trainings. He found that one particular chemical - Gamma Butyrobetaine - is being deplenished under physical workloads. He changed this molecule by replacing one atom of Silicon with that of Nitrogen so that the new molecule would not decompose and could act as a transmitter from CNS to peripheral cells.
Mildronate was approved for use to general public in 1984. It is a metabolic enhancer that can normalise cellular energy metabolism. As such, it is usually used to treat angina, myocardial failure and reduce alcohol withdrawal symptoms. Off - label use of Meldonuim in otherwise healthy individuals includes increasing exercise tolerance, learning, memory and even sexual function.
Mildronate gained popularity after Sharapova, a famous tennis player, said that she has been taking this drug for the last 10 years because of healthy reasons. Also, a number of other world and olympic champions admitted taking it., e.g. world record holder in short track - Semen Elistratov, olympic champion figure skater - Ekaterina Bobrova, racing cyclist from team Katyusha - Eduard Varganov, world champion weightlifter Aleksey Lovchev and world champion runner from Sweden - Abeba Aregawi
Interesting facts about Mildronate:
- Latvia is selling about 70 million Euro of Mildronate annually, which is about 0.7% of the total exports of this country.
- The creator of the drug, professor Ivars Kalvins, claims that Meldonium has never been found to have anabolic properties; it is rather a cardioprotector that can protect cardiovascular system of athletes from ischemia under high physical workloads. He also says, that, as such, most athletes actually should use it to diminish the negative effects associated with high-intensity trainings.
- In 2015, 17% of Russian athletes were tested positive for Meldonium, compared with 2.2% athletes of other nationalities.
- Like Semax and Cerebrolysin, Mildronate is on the Russian List of Vital & Essential Drugs.
We recommend you this video explanation of Mildronate's effect in the cell.
Here you can read more TopBrainBoosters Review of Mildronate
Country of Manufacture: Latvia
Availability: in stock