Dosage and administration
The drug is administered perorally according to the following schedule:
First 3 days: 1 tablet 6 times daily (every 2 hours) with a parallel reduction of the number of cigarettes smoked. If the result is unsatisfactory, the treatment is discontinued and a new therapy can be resumed after 2-3 months. In case of good effect, the treatment should continue according to the following schedule:
from the 4th to 12th day - 1 tablet every 2,5 hours (5 tablets daily);
from the 13th to 16th day - 1 tablet every 3 hours (4 tablets daily;)
from the 21st to 25th day - 1-2 tablets daily.
Complete discontinuation of smoking must occur by the 5th day of treatment.
The high doses may provoke nausea, vomiting, dizziness, tachycardia and muscle weakness. These effects pass quickly after the dose is decreased. .
The drug should be administered carefully to patients with exacerbated peptic ulcer. After completing the treatment course, the patients should refrain from smoking even one cigarette, in order to obtain a lasting effect. .
Country of Manufacture: Bulgaria
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Back in 1865 Acad. A.Orehov detects and analyzes the chemical cytisine contained in the group of plants known as leguminous and main active ingredient in Tabex®. Cytisine belongs to the group of nicotinic blockers, which are known in the clinical practice as respiratory stimulators. Pharmacological studies of Cytisine in the Department of Pharmacology at the Medical Institute – Sofia started in the 1950s, in which the objective was to create ampoule formula for the needs of the reanimation.
During experimental studies on anaesthetised cats, two famous Bulgarian pharmacologists – prof. Paskov and Dr. Dobrev arrived at the important conclusion that due to the little toxicity of nicotine and mostly because its’ weaker peripheral effect on the circulatory system , Cytisine can be used as a means of quitting smoking as it interacts with the same receptors in the human body that nicotine does.
The funny thing about this story is that half a century ago two heavy smokers-pharmacologists worked on developing the idea how to give people dependent of cigarettes a lighter opportunity to undergo withdrawal syndrome (a condition of a bad mood, irritability, headache, etc.) accompanying quitting while to feel invigorated as Cytisine has a proven antidepressant effect.
In 1962 in Bulgaria Prof. Isaev isolated Cytisine from yellow acacia, imitating an intensive research on the creation of the original medicinal product Tabex®. Following large clinical trials in Bulgaria, Germany, Poland and New Zeland confirmed its effectiveness. It is well known that depressive moods and abstinence syndrome are the most difficult to solve mental conditions that accompany any dependency.
Country of Manufacture: Bulgaria
This product has not been approved by the US FDA. All statements on this page are for informational purposes only and have not been evaluated by the US FDA.
This product is not intended to diagnose, treat, cure, or prevent any disease.