Dosage and administration
The dosage is one capsule (40 mg) twice or thrice daily. The length of the treatment course should not be less than three months. The first clinical improvement is typically observed after the first month of treatment.
- Allergic reactions;
- Hearing impairments;
- Erosive gastritis;
- Peptic ulcer of the stomach and duodenum;
- Acute cerebrovascular disorders;
- Acute myocardial infarction;
- Patient's age under 18 years old.
It is not recommended to take Bilobil during pregnancy and lactation due to the lack of clinical data.
The drug should not be used by patients who take Aspirin and anticoagulants (including Warfarin) on a regular basis. Coadministration with these drugs may increase the risk of bleeding due to prolongation of blood clotting time.
If you experience vertigo or tinnitus please consult with a healthcare practitioner.
If you suddenly experienced hearing loss or impairment you should see a doctor immediately.
The drug contains lactose, thus should not be taken by lactose intolerant patients.
In very rare cases, azo dyes (E110, E124 and E151) may contribute to the development of bronchospasm.
Tanakan ® is a standardized extract of ginkgo biloba leaves. Ginkgo biloba known as one of the oldest living tree species on earth and its use in traditional medicine dates back to 3000 BC.
It is used in the treatment of cerebrovascular disorders, dementia, decreased mental capacity and tinnitus. Ginkgo extract also widely used in various OTC nootropic supplements.
The first pharmaceutical preparation of Ginkgo biloba was introduced in 1965 by German company “Dr. Willmar Schwabe Pharmaceuticals” under the trade name of Tebonin. Back then, it was one of the most widely prescribed drugs in Germany with more than 5 million prescriptions in 1988.
EGB 761 is the active ingredient of Tanakan @ and other pharmaceutical Ginkgo extracts including Tebonin. It is a standardized extract of Ginkgo biloba leaves, which consists of 24% flavone glycosides, 6% terpene lactones, bilobalide, and ginkgolides. EGB 761 is the golden standard of Ginkgo biloba supplementation and was used in hundreds of various clinical trials.
Because of the complex composition of the extract, its mechanism of action is also complex and diverse. The pharmacological effect of Tanakan relies mostly on its vasodilatory and neuroprotective properties. Ginkgo biloba is known to improve cerebral circulation, which is especially beneficial for elderly patients and patients with cerebrovascular disorders.
Neuroprotective effect of the drug is mediated by its antioxidant and free radical scavenging action, which may be responsible for its moderate anxiolytic and antidepressant effects that was demonstrated in some studies.
Here, you have a choice of several Gingko Biloba products of various manufacturers and different sizes. Bilobil is produced by a Slovenian company KRKA, Tanakan is produced by a French company IPSEN and Gingko Biloba extract is produced by a Russian company Vertex.
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- Sadowska-Krępa (2017) Effects of Six-Week Ginkgo bilobaSupplementation on Aerobic Performance, Blood Pro/Antioxidant Balance, and Serum Brain-Derived Neurotrophic Factor in Physically Active Men https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5579597/