Tiolepta is an endogenous antioxidant that binds free radicals and stabilizes lipid and carbohydrate metabolism. Thioctic acid (alpha-lipoic acid), its main component, is an organosulfur compound derived from caprylic acid. It is an antioxidant that is widely used as a dietary supplement and as a pharmaceutical drug. Alpha-lipoic acid is most commonly used to treat diabetes and nerve-related symptoms of diabetes including burning, pain and numbness in the legs and arms. Alpha-lipoic acid is used in the body to break down carbohydrates and to make energy for other organs. It helps prevent certain kinds of cell damage and also restores vitamin E and vitamin C levels.

Alpha-lipoic acid has hepatoprotective, lipid-lowering, hypocholesterolemic and hypoglycemic properties. It lowers blood glucose by binding to insulin receptor in the body which increases glucose utilization. Also, due to its antioxidant activity, alpha-lipoic acid is used to treat nerve damage due to uncontrolled blood sugar level that causes pain, tingling, or numbness over hands and feet (diabetic neuropathy).

Indications

Diabetic neuropathy and alcoholic polyneuropathy.

Counterindications

  • hypersensitivity to the components of the drug;
  • pregnancy and lactation;
  • children under 18 years of age;
  • lactose intolerance, lactase deficiency or glucose-galactose malabsorption (for tablets).