Afobazole Fabomotizole

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Afobazole® (Fabomotizole)

16 Reviews

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$27.55 /item
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$26.97 /item
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$26.39 /item
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$25.81 /item
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$25.52 /item
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$25.23 /item
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$24.94 /item
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$24.65 /item
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For more information on Afobazole dosages and side effects, please refer to the translated official drug sheets linked below.

  1. Neznamov et al (2001) Clinical study of the selective anxiolytic agent afobazol 
  2. VS Kudrin (2006) A comparative study of the effect of afobazole on brain monoamine systems in BALB/C and C57BL/6 mice 
  3. A Uyanaev, V Fisenko (2006) Studies of long-term noopept and afobazol treatment in rats with learned helplessness neurosis 
  4. Davydova et al (2010) Neurochemical study of effects of the new anxiolytic drugs afobazol and ladasten on the synthesis and metabolism of monoamines and their metabolites in the brain structures of Wistar rat on the model of monoamine synthesis blockade induced by aromatic amino acid decarboxylase inhibitor NSD-1015 
  5. Reutova et al (2010) Anxiolytic afobazole action self-evaluated by patients with anxiety-asthenic disorders 
  6. Volkova et al (2010) Comparative study of the interoceptive effects of afobazole and diazepam
  7. Kryzhanovskyi et al (2011) Study of anti-ischemic effect of afobazole in experimental myocardial infarction 
  8. Cuevas et al (2011) Afobazole modulates microglial function via activation of both sigma-1 and sigma-2 receptors 
  9. Seredenin et al (2013) On the mechanism of anti-ischemic effects of afobazole 
  10. Behensky et al (2013) Afobazole activation of σ-1 receptors modulates neuronal responses to amyloid-β25-35 
  11. Kadnikov et al (2015) Cytoprotective Effect of Afobazole and Its Main Metabolite M-11 
  12. TS Syunyakov, GG Neznamov (2016) Evaluation of the therapeutic efficacy and safety of the selective anxiolytic afobazole in generalized anxiety disorder and adjustment disorders: Results of a multicenter randomized comparative study of diazepam
  13. Kryzhanovkii et al (2018) On the Mechanism of the Cardioprotective Action of σ1 Receptor Agonist Anxiolytic Fabomotizole Hydrochloride (Afobazole) 
  14. Ostrovkaya et al (2018) Antidiabetic Activity of Afobazole in Wistar Rats 
  15. Kapitsa et al (2019) Afobazole Alleviates Cognitive Rigidity in Experimental Model of Autism Spectrum Disorders 
  16. Ivanov et al (2020) Analysis of Cytoprotective Properties of Afobazole in Streptozotocin Model of Diabetes 
  17. Kryzhanovskii et (2021) Angiogenic Effects of Anxiolytic Fabomotizole 

4.6

Based on 16 Reviews

(13)

(2)

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(1)

 

04/26/2025

J

J

 Verified Buyer
US

US

I Didn’t Expect Much—But Fabo Delivered Big Time

This stuff was honestly incredible in a way that snuck up on me. When I first started taking it, I was dealing with anxiety so intense it felt like I was having mild panic attacks—tight chest, shortness of breath, the whole thing. It was overwhelming. I started to notice some small improvements during the first month, but by the second month, Fabo really started to work its magic. I felt noticeably better. I ended up using it consistently for eight months and never experienced any negative side effects. Why aren’t other pharmaceutical companies making something similar?

04/27/2025

CosmicNootropic

Thank you so much for sharing your experience! It means a lot to hear how much Afobazole helped you, especially during such a tough time. We’re so happy you gave it a chance and stuck with it long enough to feel the full benefits.

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0

03/07/2025

Sandra L.

Sandra L.

 Verified Buyer
US

US

Effective Chill Pill

Works well to alleviate work and situational stress without side effects or feeling sedated. Taking as needed. Helps me to sleep too. Highly recommended.

03/07/2025

CosmicNootropic

Dear Sandra, Thank you for sharing your experience. We really appreciate your feedback!

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0

12/02/2024

MH

Morgan H.

 Verified Buyer
US

US

Icky product

Made me feel anxious, gave me a headache, felt sick

12/03/2024

CosmicNootropic

Dear Morgan, we’re sorry to hear that you had a negative experience with Afobazole. As we mentioned earlier, everyone’s body can react differently to supplements, and while many people find it helpful, it may not be suitable for everyone. We always recommend consulting with a medical professional before trying any new product.

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0

07/19/2024

Sam

Sam

 Verified Buyer
IL

IL

AMAZING

First of all this is an anxiolytic with no sedative or muscle relaxation, which is very good because it has low potential for abuse, this is amazing for anxiety. sometimes if I feel 1 pill isn\'t enough I take another

07/19/2024

CosmicNootropic

Hi Sam! Thank you so much for sharing your experience with us! We're thrilled to hear how our product has been beneficial for managing your anxiety effectively. It's great to know that you find it to be such a valuable tool in your wellness routine.

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0

05/23/2024

S

Steve

 Verified Buyer
US

US

Great option for SAD

This has been great for my seasonal depression. The tablets are small and easy to take. It begins working in a few days. It\'s helped to reduce my anxiety and get back into my normal routines. There have been no side effects and no withdrawal symptoms. I have been on Paxil, which works well, but has some side effects and I was concerned about long-term use. Only downside with Afobazole is remembering to take it three times a day, but I just take it with meals. There is a 30mg, extended release version, but I haven\'t been able to find that for sale anywhere online.

05/24/2024

CosmicNootropic

Hi Steve! Thank you for your review! We are glad to hear that Afobazole has been helpful for you.

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0

07/02/2022

P

Pettclan

 Verified Buyer
US

US

Cheap quick and easy

AFOBAZOLE is the go-to generic anti-anxiety. It will only take the edge off the hard stuff. But for everyday things it can't be beat. If you need the edge taken off the knife of anxiety, this is it. It's not going to deal with major stuff, but sometimes a little is alot. For me it allows me to deal with anxiety instead of removing it. Anxiety is still there, but so much easier to deal with. People say I'm not as "on edge" while on it. The price can't be beat, and the shipping is fast. For cheap quick easy stuff, this is it. If you need something stronger, there are other things out there.

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0

11/01/2021

MP

Mr P.

 Verified Buyer
US

US

Better than I thought it would be

Since this was one of the least expensive anti-anxiety meds, I figured it would just work just a little bit. I was pleasantly surprised. Bought it for my daughter who has BAD anxiety. For her she says it feels like her anxiety is both there and not there at the same time. So it does help her in a way, which is good. I don't have anxiety, but I do have a lot of stress and worries. For me it makes me just forget I'm stressed or worried about things. I can get things done and deal with things much easier. I'll definitely be ordering again. It doesn't make either of us tired or "spacey" which is nice.

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0

06/12/2020

TL

Tony L.

 Verified Buyer
US

US

Awesome again..,

Every aspect of dealing with these guys is easy and professional.

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0

07/11/2019

DL

David L.

 Verified Buyer

Responsible Merchant

Prompt and transparent shipping. Products are authentic and as described. Packaging is discrete and appropriate.

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0

09/14/2018

LG

Lane G.

 Verified Buyer

Afobazole x120 Tabs, Emoxypine x50

Great Communication, Fast shipping. Reliable. Would buy again

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0

08/01/2018

EB

Emiel B.

 Verified Buyer

Staple of my anxiolytic stack

One of the best additions to my anti anxiety stack. No side effects whatsoever, non sedating, but very active at reducing anxiety. Can absolutely recommend this product!

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0

08/01/2018

EB

Emiel B.

 Verified Buyer

Staple of my anxiolytic stack

One of the best additions to my anti anxiety stack. No side effects whatsoever, non sedating, but very active at reducing anxiety. Can absolutely recommend this product!

Was this helpful?

0

02/20/2017

JO

Jeff O.

 Verified Buyer

Reset My Emotional State

After years of being kicked around by life, I was in a sorry place mentally - sad, lacking confidence, and quick to hostility. I ordered Afobazole and began taking it 3x per day. I didn't notice any specific feeling from it, but after one week I could tell it was working. I was becoming less emotional than before. I finished the box (20 days total) and I must say that I am very impressed with the results. Afobazole "fixed" me and I feel like a new man.

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0

02/08/2017

R

Robert

 Verified Buyer

Overall very nice experience

I personally don't feel very incapacitated when I use it but I much prefer taking this after a long day's work because it puts me in the mood to relax and sleep. For me this supplement pretty much kills any effects from stimulants I'm taking (which I sadly found out yesterday morning when I had work to do). My recommendation would be to try this supplement at night after you have all your work done, then consider the effects it has on you and implement it into a non-busy workday. That being said, I'm a laidback guy. If you have serious anxiety this might calm you down to a regular level.

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0

10/31/2016

M

Mattikus

 Verified Buyer

Mild but side effect free

Noticed a slight calming effect, and may have slept a little better while using. Hard to say as I generally have no problem with anxiety. Never had any negative effects at all, and never felt sedated like some anxiolitics can cause.

11/30/-0001

CosmicNootropic

Hi Mattikus, thank you for the feedback! Most if our products are intended to normalize brain functions, not to improve them greatly of you are already healthy. Best regards, Andrey

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0

04/12/2016

R

Roi

 Verified Buyer

Anxiolytic, maybe a little sedating, works good with stimulants.

First of all, I want to mention that there is a high probability this drug works on Melatonin receptors. When I take Melatonin I notice nightmares as a side effect and wake up groggier than usual (I always wake up groggy no matter how much I sleep). I have been taking Afobazole for around 2 weeks. I didn't take it at the recommended dosage of 3 tablets per day because I never felt a clear acute effect and read online that people managed with 2 tablets per day. I have finished 27 tablets. There are days I only took 1 and a day I tried 3. Never felt diminished or increased effects, except maybe when I took the dosage with some stimulants like Ritalin and coffee (no heart issues or anxiety). I can say it works for social anxiety, but nothing like Phenibut, which is also stimulating. Today at class I could keep a prolonged eye contact with a girl, something I find normally very hard since childhood. To be honest, I actually have a problem to keep an eye contact with males too (I'm 27 soon). I'm going to stop the medication in about a week and see what happens. Then, I will use what I got left. I will update if there is anything interesting.

11/30/-0001

CosmicNootropic

Thank you, Roi! Another great and deep review from you! We are happy that you enjoy our products. Best regards, Andrey

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0
< 1 >

9 months ago

Review

J Verified Buyer

I Didn’t Expect Much—But Fabo Delivered Big Time

This stuff was honestly incredible in a way that snuck up on me. When I first started taking it, I was dealing with anxiety so intense it felt like I was having mild panic attacks—tight chest, shortness of breath, the whole thing. It was overwhelming. I started to notice some small improvements during the first month, but by the second month, Fabo really started to work its magic. I felt noticeably better. I ended up using it consistently for eight months and never experienced any negative side effects. Why aren’t other pharmaceutical companies making something similar?

Reply:

Thank you so much for sharing your experience! It means a lot to hear how much Afobazole helped you, especially during such a tough time. We’re so happy you gave it a chance and stuck with it long enough to feel the full benefits.

Response

8 years ago

Review

Emiel B. Verified Buyer

Staple of my anxiolytic stack

One of the best additions to my anti anxiety stack. No side effects whatsoever, non sedating, but very active at reducing anxiety. Can absolutely recommend this product!

Response

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