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All statements on this page are for informational purposes only and have not been evaluated by the US FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Before using this product, consulting a qualified MD is mandatory. See more

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Anxiolytics are supplements that reduce and prevent anxiety and related symptoms. They are popular among people who are looking to have a calming effect, reduce irritability, elevate mood and improve sleep quality.

Please note that due to regulations Anxiolytics Bundle can only be shipped to the US because it contains Phenibut.

What is inside the Anxiolytics Bundle?

Anxiolytics Bundle contains samples of five bestsellers that we have hand-picked for you based on their effectiveness and safety.

Product Name Amount of the
active substance
Number of Pills
      in the Bundle 

Phenibut 250 mg 10 pills Organica
Mexidol 125 mg 10 pills Pharmasoft
Adaptol [Mebicar] 30 mg 10 pills TatChemPharmPreparaty
Picamilon 50 mg 30 pills PharmStandard
Afobazole 10 mg 30 pills OTCPharm

How to take Anxiolytics Bundle?

The optimal way to take anxiolytics in the bundle is in sequence, with 2-3 week intervals. In this manner you can track the effects and pick out an anxiolytic or a stack that works best for you.

Product Name Dosage
(Pills Per Day)
  Days of Use

Phenibut 1-5 pills 2-10 days
Mexidol 2-4 pills 2-5 days
Adaptol [Mebicar] 2-6 pills 2-5 days
Picamilon 2-3 pills 10-15 days
Afobazole 3 pills 8 days

Why shall I buy Anxiolytics Bundle?

This Bundle is for those who like to try popular anti-anxiety medications and mood-elevators or who look for the perfect anxiolytic stack. Since every person is unique, you can learn which product is right for you only after sampling it. Take a serious approach to your well-being and health, try out this Anxiolytics Bundle.

What are the benefits of Anxiolytics Bundle?

  • First of all, the supplements in the Bundle have been extensively studied and used in the post Soviet countries and each of them has dozens of papers on pubmed.
  • Secondly, they are produced officially by reputable manufacturers in compliance with local and international requirements.
  • Thirdly, this anxiolytics sample pack is money-saving. You get 5 bestsellers at 1/3 of the price you would spend if you bought them separately.

Why do healthy people take Anxiolytics?

We often face stress in the everyday life. Sometimes the stress levels run so high that people find themselves resorting to alcohol, smoking and other ways to feel better. But this is not the healthiest way of dealing with stress. Do you want to give up your bad habits and maintain both mental and physical health? With Anxiolytics this process is going to be much more effective and much easier for you.

Also, check out Nootropics and Adaptogens bundles.

What is included in the Anxiolytics Bundle?

1. Phenibut (10 pills)

Active ingredient: γ-amino-β-phenylbutyric acid hydrochloride — 250 mg. 

Excipients: lactose,potato starch, calcium stearate.

Instructions: Orally, during or after meals. The maximum single dose is 750 mg. Shall not be taken for extended periods of time. Tapering-down is recommended. Average daily dose is 2-5 pills. 

2. Mexidol (10 pills)

Active ingredient: ethylmethylhydroxypyridine succinate — 125 mg.

Excipients: lactose monohydrate — 97.5 mg; povidone — 25 mg; magnesium stearate — 2.5 mg.

Instructions: Orally, regardless of food intake. Duration of the course is determined individually. Average dose is 1-2 pills 3 times a day; the maximum daily dose is 800 mg.

3. Mebicar (10 pills)

Active ingredient: Temgicoluril — 300 mg.

Excipients: povidone — 1.5 mg, calcium stearate — 1.5 mg.

Instructions: Orally, regardless of food intake. Average dose is 1-4 pills 2-3 times a day. The maximum single dose is 3 g, the maximum daily dose is 10 g.

4. Picamilon (30 pills)

Active ingredient: N-nicotinoyl-GABA — 50 mg.

Excipients: potato starch, magnesium hydroxycarbonate hydrate, talc, sucrose, stearic acid or calcium stearate.

Instructions: Orally, regardless of food intake. Average dose is 30–50 mg, once or twice a day.

5. Afobazole (30 pills)

Active ingredient: fabomotizole substance — 10 mg. 

Excipients: potato starch, microcrystalline cellulose, lactose, povidone, magnesium stearate.

Instructions: Orally, regardless of food intake. Dosage and duration of the course are determined individually. Average daily dose is 3 pills. 

Storage Conditions

At a temperature not higher than 25°C (77°F) in a dry dark place. Keep out of reach of children.


Do not use it if you are under 18 y.o., pregnant or breastfeeding, or if you have any known or suspected medical conditions. In case of any allergic reactions or high blood pressure the supplement shall be discontinued.

Research behind the Anxiolytics Bundle

All supplements in the bundle are well studied. You can find many research papers on each of them. We highlighted a few below. More links are available on the product pages.



  1. Owen et al (2016) Phenibut (4-amino-3-phenyl-butyric acid): Availability, prevalence of use, desired effects and acute toxicity
  2. Volotova et al (2016) Neuroprotective action of phenibut and neuroglutam in experimental cerebral ischemia on the background of altered immunoreactivity
  3. Vavers et al (2016) The neuroprotective effects of R-phenibut after focal cerebral ischemia


  1. Androfagina et al (2015) Mexidol in the rehabilitation of patients in the acute ischemic stroke
  2. Gromova et al (2018) Experience with mexidol in neurological practice
  3. Shamrey et al (2020) [Possibilities of using Mexidol in the complex therapy of mental disorders]
  4. Voronina et al (2022) [The role of oxidative stress in hemorrhagic stroke and restorative effects of Mexidol]

Adaptol [Mebicar]

  1. V Vorob’eva, V Repina (2016) An open comparative observational study of the efficacy and safety of adaptol in anxiety-asthenic disorders in patients with chronic cerebral ischemia
  2. J Zhitkova, D Hasanova (2017) An experience of using mebicar in patients with autonomic dysfunction associated with anxiety disorder
  3. Kotova et al (2022) [Sleep disorders in post-COVID syndrome – a problem of psychiatry or neurology?]


  1. I Sapegin, A Beketov (1993) The effect of pikamilon and fenibut on the blood supply of the brain at rest and under gravitational exposures
  2. Silkina et al (2005) Gabaergic mechanism of cerebrovascular and neuroprotective effects of afobazole and picamilon
  3. Likhodeev et al (2009) Effects of aminalon, fenibut, and picamilon on the typological parameters of cerebral hemodynamics in swimmers with dysadaptation syndrome


  1. Seredenin et al (2013) On the mechanism of anti-ischemic effects of afobazole
  2. Kadnikov et al (2015) Cytoprotective Effect of Afobazole and Its Main Metabolite M-11
  3. Kryzhanovkii et al (2018) On the Mechanism of the Cardioprotective Action of σ1 Receptor Agonist Anxiolytic Fabomotizole Hydrochloride (Afobazole)
  4. Kryzhanovskii et (2021) Angiogenic Effects of Anxiolytic Fabomotizole


Based on 3 Reviews








Richard B.

Richard B.

 Verified Buyer


Nice variety

Interesting trying out different nootropics. Like the idea getting in actual pill form so can be sure getting right dosage. Made me interested in more future purchases.


Dear Richard, We're glad to know you liked our anxiolytics bundle! Hope to see you as our customer again soon.

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 Verified Buyer



Loved figuring out what works best for me. The bundle made it easy.


Hi Valerie! thank you for your kind feedback! We're thrilled to hear that you are satisfied with our product :)

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This is good


Hi Nikolass, thank you for your feedback!

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