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CORTEXIN ®
45 Reviews
Buy Cortexin® Online!
Cortexin is a complex of low molecular weight neuropeptides, amino acids, and vitamins derived from the cerebral cortex of cattle. Cortexin is similar to Cerebrolysin, but it has a significantly larger amount of peptide fractions and fewer amino acids.
One Course is 1 pack x 10 ml vials for 10 days. The course can be repeated in 3-6 months.
Chemical name | Cortexin |
Form: | 10 vials of 5mg / 10 vials of 10mg |
Form description: | Lyophilized powder or porous mass of white or white-yellowish color |
Active ingredient: | Cortexin® (complex of water-soluble polypeptide fractions): 5 mg in a 3 ml vial, and 10 mg in a 5 ml vial |
Excipients: | Glycine (stabilizer) – 6 mg in a 3 ml vial and 12 mg in a 5 ml vial. |
СAS Number: | 83270-84-2 |
ATC code: | N06BX |
Pharmacological action: | Neuroprotective, nootropic, antioxidant, tissue-specific |
Shelf life: | 3 years. Do not use it beyond the expiration date printed on the package. |
Storage conditions: | Store in a dry dark place at temperatures no higher than 25°C (77°F). Keep in a safe place out of reach of children. |
Terms of release: | Over-the-counter |
Manufacturer: | Gerofarm, Russia https://geropharm.com/ |
What is Cortexin?
Cortexin is a mixture of neuropeptide fractions, amino acids, vitamins, and minerals, all of which have a mild positive effect on the brain. Similar to Cerebrolysin, Cortexin is based on neuropeptides and amino acids. While the former is produced from pig brains only, the latter is extracted mostly from young horned cattle cerebral cortex by acetic acid extraction. For more information on the comparison of the two compounds please read our blog post.
Cortexin comes in injection form only: 10 mg – for adults, and 5 mg – for children.
What are the Benefits and Effects of Cortexin?
Cortexin has the following effects:
- Nootropic effect: it improves higher cerebral functions, processes of learning and memory, concentration, attention, and tolerance to mental and physical stress;
- Neuroprotective effect: Cortexin protects neurons against different endogenous neurotoxic factors (glutamate, calcium ions, and free radicals) and reduces the toxic impact of psychotropic agents;
- Antioxidant effect: Cortexin inhibits lipid peroxidation, and increases the survival of neurons under oxidative stress and hypoxia;
- Tissue-specific effect: this drug activates the metabolism of neurons of the central and peripheral nervous system as well as reparative processes; also, it promotes stimulation of cortical function and general improvement of the nervous system.
Wonder what the difference is between Cortexin and Cerebrolysin?
The answer is in the Cortexin video review via the link below ⏬
What is Cortexin Used for?
Intended uses of Cortexin are defined by its correction of impaired molecular and cellular processes. Cortexin injections are prescribed in the following cases:
- cerebral circulation disorders;
- encephalopathy of various genesis;
- acute and chronic encephalitis and encephalomyelitis;
- epilepsy;
- traumatic brain injury and its consequences;
- asthenia;
- infantile cerebral palsy;
- psychomotor and speech retardation in children;
- cognitive disorders (dysfunction of memory and ideation);
- reduced learning ability.
There is evidence that Cortexin may relieve post-COVID syndrome. [19]
What is Cortexin Composition?
Amino acids: Aspartic acid – 446 nmol/mg; Glycine – 298 nmol/mg; Threonine – 212 nmol/mg; Serine – 268 nmol/mg; Glutamic acid – 581 nmol/mg; Proline – 187 nmol/mg; Alanine – 246 nmol/mg; Isoleucine – 356 nmol/mg; Tyrosine – 109 nmol/mg; Phenylalanine – 162 nmol/mg; Histidine – 116 nmol/mg; Lysine – 253 nmol/mg; Arginine and other amino acids – 202 nmol/mg.
Vitamins: Lysine – 253 nmol/mg; Thiamine (Vitamin B1) – 0.08 mcg/10mg; Riboflavin (Vitamin B2) – 0.03 mcg/10 mg; Niacin (Vitamin B3, Vitamin PP) – 0.05 mcg/10 mg; Retinol (Vitamin A) – 0.011 mcg/10mg; Alfa-tokoferol (vitamin E) – 0.007 mcg/10mg.
Minerals: (Cu) – 0.2129 mcg/10 mg; (Fe) – 2.26 mcg/10 mg; (Ca) – 22.93 mcg/10 mg; (Mg) – 8.5 mcg/10 mg; (K) – 19.83 mcg/10 mg; (Na) – 643.2 mcg/10 mg; (S) – 152.65 mcg/10 mg; (P) – 91.95 mcg/10 mg; (Zn) – 4.73 mcg/10 mg; (Mb) – 0.0203 mcg/10 mg; (Co) – 0.0044 mcg/10 mg; (Mn) – 0.0061 mcg/10 mg; (Se) – 0.0745 mcg/10 mg; (Al) – 0.3104 mcg/10 mg; (Li) – 0,0340 mcg/10 mg.
Where Can I Order Cortexin Online?
You can order Cortexin online from different vendors. CosmicNootropic offers Cortexin in packs of 10x5mg and 10x10mg vials with worldwide shipping! Always be sure to do your research before purchasing any nootropic supplement to ensure you are getting a quality product.
You can order Cortexin and get it delivered to the USA, Europe, the UK, Asia, and many other destinations via CosmicNootropic.
What is Cortexin Dosage, How To Use?
Cortexin has indication-specific dosing. The most common regime is intramuscular injections once daily: 10 mg per day for a period of 10 days for adults. For pediatric dosage please refer to the official instruction. If necessary, the course can be repeated after 3–6 months of discontinuation.
Cortexin shall be taken in the first part of the day, before 3 p.m.
Please use sterile needles, sterilize the administration site, wear sterile plastic gloves, and administer as soon as you open the vial. Before injection dissolve the content of the vial in 1-2 ml of 0.5% procaine (Novocain) solution, water for injection, or 0.9% sodium chloride solution. Relax your muscles and inject slowly.
What are the Side Effects of Cortexin?
No adverse reactions were observed during administration when taken as indicated. Individual hypersensitivity to the product components is possible. Please pay close attention to your body response when you administer the drug for the first time.
OFFICIAL INSTRUCTION
- Coulter et al (1993) Identification of cortexin: a novel, neuron-specific, 82-residue membrane protein enriched in rodent cerebral cortex https://www.ncbi.nlm.nih.gov/pubmed/8336151
- Khavinson et al (1999) Cortexin effectiveness in circulatory encephalopathy https://www.ncbi.nlm.nih.gov/pubmed/10356917
- Shabanov et al (2007) Comparison of behavioral effects of cortexin and cerebrolysin injected into brain ventricles https://www.ncbi.nlm.nih.gov/pubmed/18214294
- Shabanov et al (2007) Comparative study of behavioral effects of cortexin and cerebrolysine upon intraventricular and intraperitoneal administration in rats https://www.ncbi.nlm.nih.gov/pubmed/17650626
- Nurguzhaev et al (2009) Use of cortexin in the early rehabilitation period of ischemic stroke of moderate severity https://www.ncbi.nlm.nih.gov/pubmed/19672239
- B Gafurov, Sh Gafurov (2010) Cortexin in the complex treatment of post stroke epilepsy https://www.ncbi.nlm.nih.gov/pubmed/20873481
- A Solov’ev, T Elistratova (2010) Effectiveness of cortexin in the complex treatment of patients with chronic alcohol encephalopathy and polyneuropathy https://www.ncbi.nlm.nih.gov/pubmed/20517210
- Mendzheritsky et al (2015) Pinealon and Cortexin influence on behavior and neurochemical processes in 18-month aged rats within hypoxia and hypothermia https://www.ncbi.nlm.nih.gov/pubmed/28509493
- Belova et al (2016) Efficacy of cortexin in acute and recovery periodes of hemispheric ischemic stroke https://www.ncbi.nlm.nih.gov/pubmed/27845314
- Yakovlev et al (2017) Peptide drug cortexin inhibits brain caspase-8 https://www.ncbi.nlm.nih.gov/pubmed/28251948
- A Yakovlev, N. Gulyaeva (2017) Molecular partners of Cortexin in the brain https://link.springer.com/article/10.1134/S1819712416040164
- Zukov et al (2018) Results of a multicenter study on the efficacy of cortexin in treatment of cognitive dysfunction in children ttps://www.ncbi.nlm.nih.gov/pubmed/29652302h
- N Gulyaeva (2018) Molecular mechanisms of brain peptide-containing drugs: cortexin https://www.ncbi.nlm.nih.gov/pubmed/30499504
- A Fedin (2018) The efficacy of cortexin and memantinol (memantine) in the treatment of cognitive impairment in patients with chronic cerebral ischemia https://www.ncbi.nlm.nih.gov/pubmed/29460902
- Belova et al (2018) Efficacy of Korteksin in acute period of hemispheric ischemic stroke https://www.ncbi.nlm.nih.gov/pubmed/30132453
- Fedin et al (2018) Dose-dependent effects of cortexin in chronic cerebral ischemia (results of a multicenter randomized controlled study) https://www.ncbi.nlm.nih.gov/pubmed/30335070
- Gulyaeva (2019) Molecular Mechanisms of the Actions of Brain Peptide-Containing Drugs: Cortexin https://link.springer.com/article/10.1007/s11055-019-00839-4
- Mashin et al (2019) [Evaluation of the efficacy and safety of application of the drug cortexin in the complex rehabilitation of verticalization in patients with ischemic stroke in the acute period] https://pubmed.ncbi.nlm.nih.gov/31626220/
- Putilina et al (2022) [Determination of the prevalence of postcovid syndrome and assessment of the effectiveness of the drug Cortexin in the treatment of neurological disorders in patients with postcovid syndrome. Results of the multicenter clinical and epidemiological observational program CORTEX] https://pubmed.ncbi.nlm.nih.gov/35175707/
4.5
Based on 45 Reviews
(37)
(2)
(1)
(0)
(5)
09/22/2024
Brandon
Verified BuyerUS
Cortexin
Has anyone tried injecting this IV instead of IM? I am doing this and have great results I also adminiter IV with Cerebrolysin and it\'s the best result.
10/07/2024
Cosmic Nootropic
Thanks for sharing your experience with Cortexin and Cerebrolysin! It's great to hear that you’re achieving such positive results with IV administration. However, it is important to note that according to the official instructions, Cortexin is meant for IM administration only. Everyone's body responds differently, so it’s always interesting to hear about different methods. Just a reminder to consult with a healthcare professional when experimenting with any treatments. If you have any more insights or questions, feel free to share!
09/18/2024
Ivan W.
Verified BuyerUS
Helps reverse methamphetamine brain damage
Was ****** and abused methamphetamine that my parents BOUGHT ME. Got severe brain damage visible on a PET scan. Also pill mill doctors overprescribing me Adderall saying it'll help me (it did nothing good) Reduced my persistent anxiety from the damage and more motivation. Very expensive. It was like about $6000 to cause the damage it'll take half that amount to reverse repair it.
09/20/2024
Cosmic Nootropic
Hi Ivan! Thank you for sharing your experience. It's clear that you've been through a lot, and we appreciate your openness. It’s important to mention that individual experiences can vary greatly, and what works for one person may not work for another. We always recommend consulting with a qualified healthcare professional before making any decisions about treatment or medication. Your journey is unique, and it's vital to seek personalized advice tailored to your needs. Wishing you the best on your path to recovery.
09/10/2024
Brandy P.
Verified BuyerUS
Amazing
My husband and I both love this product. We stack it with Cerebro and I swear we have super powers, lol. Super sharp recall , fog lifted, feel amazing.
09/11/2024
Cosmic Nootropic
Hi Brandy! Thank you so much for your enthusiastic review! We're thrilled to hear that Cortexin and Cerebrolysin are working wonders for you and your husband. It's fantastic to know that this product worked for you :)
08/13/2024
Kevin
Verified BuyerFR
It works long after
It doesn\'t give me super brain, but it gives me an appreciable cognitive boost, especially for my memory. And best of all, the effect lasts a long time after the 10 dose course ends. For 2 months after I did my first course, I never forgot where I parked! It\'s my favorite nootropic.
08/14/2024
Cosmic Nootropic
Hi Kevin! Thank you so much for your feedback! We’re thrilled to hear that our nootropic has had a positive impact on your memory and that you’ve experienced lasting benefits. It’s fantastic to know it’s become your favorite!
08/06/2024
Lina R.
Verified BuyerUS
Reliable brain support
I found both cerebrolysin and cortexin being reliably helpful for my brain function recovering from mold toxicity, lyme, other toxicities that has left me foggy, costant headaches, reduced executive functions, etc These two, I can say with certainty, have been vital in supporting my mind in finding it's way back to myself. Thank you for making this easily available and your awesome customer service with a prompt responses to my enquiries.
08/06/2024
Cosmic Nootropic
Hi Lina! Thank you so much for your thoughtful review! We’re delighted to hear that both Cerebrolysin and Cortexin have been instrumental in supporting your recovery. It’s incredibly rewarding to know our products and customer service have made a positive impact on your journey back to better health. If you have any questions or need further assistance, we’re always here to help. Wishing you continued progress and wellness!
07/28/2024
Jayc
Verified BuyerUS
For me Cortagen was more effective
I did a round of cortagen before this and it had a solid reduction effect on my palinopsia. It was super expensive so I decided to take cortexin because it was cheaper. Even though I took 4x as much cortexin than cortagen it almost didn\'t have any affect at all. I didn\'t know if that\'s because I reaped all the benefits from cortagen, if the cortexin was degraded in transport as it took a long time in transport, or if the cortagen is just that more potent.
08/02/2024
Cosmic Nootropic
Hi Jayc! Thank you for sharing your experience. We understand that cost considerations are important, and we’re sorry to hear that Cortexin didn’t meet your expectations. The effectiveness of the products can vary, and such factors as personal conditions and dosage can play a role.
07/25/2024
Jessica H.
Verified BuyerUS
Helped husband with TBI symptoms
Definitely was able to start thinking more clearly and make better decisions. Cognitive function improved greatly. Mood and temper improved as well.
07/26/2024
Cosmic Nootropic
Hi Jessica! Thank you so much for sharing your experience! We're delighted to hear that our product could make such a positive impact on your husband's life!
07/06/2024
corey r.
Verified BuyerAU
Fantastic service
Great. Super helpful when I contacted with a shipping question.
07/08/2024
Cosmic Nootropic
Hi Corey! Thank you for your wonderful feedback! We're delighted to hear that you found our service fantastic and our team helpful. Ensuring a seamless experience, from inquiries to delivery, is our goal.
05/23/2024
Sanije B.
Verified BuyerDK
terrible
It was terrible. I have not recieved my shipment and not refund! The policies of refundment are just terrible.
05/23/2024
Cosmic Nootropic
Hi Sanije! We are so sorry to hear this, thank you for reaching out. We have emailed you to see what can be done in this situation.
01/04/2024
Kevin
PK
Appreciable and lasting benefit
This is one of my top 3 nootropics. This stuff makes a noticeable difference in my focus and memory. And one 10-day course leaves a benefit that lasts a few weeks. After the first time I tried it, I never forgot where I parked for like 2 months. Normally that\'s always a problem for me. Of course it helps in other ways too besides parking.
01/04/2024
Cosmic Nootropic
Dear Kevin, we are happy to hear that you are satisfied with this product :) Thank you for leaving the review!
12/22/2023
Joshua
Great Product
After 10 years of brain fog from Lyme disease I\'m finally seeing light at the end of the tunnel. I find that cortexin gives me more mental energy and clarity. I\'m suddenly remembering the words to songs I didn\'t know I knew lol. It is also helping with my anxiety. It seems to make my brain sharper than cerebrolisyn. In 6 months I would like to do another course of cortexin with cerebrolisyn.
12/22/2023
Cosmic Nootropic
Hi Joshua! Thank you for finding a moment to leave a review. We're beyond happy to know that this product helped you with such a serious issue.
12/05/2023
Jeff D.
US
Bait and switched me
It boggles my mind that I paid for 10 vials, and they gave me a tracking # that had no cortexin in it at all. It\'s super infuriating. Only now, 11 days after paying for it, am I seeing the banner running saying you\'re out of stock. This is beyond unacceptable! People count on these meds and your company, with our lives and health depending on it, and this is what you let happen? Forcing me to source it elsewhere.
12/06/2023
Cosmic Nootropic
Dear Jeff, We understand your frustration with the temporary delays in our warehouse and we deeply apologize. Now your order is on its way and will be delivered shortly. Please check your email.
12/05/2023
Jeff D.
US
Never got what I paid for!!!
Paid for 10 vials of cortexin and never got them!!
12/06/2023
Cosmic Nootropic
Dear Jeff, your order is on its way and will be delivered shortly. Please check your email.
12/03/2023
Kyle B.
Verified BuyerUS
Never received
I would have like the product if I ever receive it.
12/15/2023
Cosmic Nootropic
Dear Kyle, we apologize for the recent delays at our US warehouse. We see now that you received your order on the Dec 11th and hope you're satisfied with the product.
11/17/2023
Joseph L.
Verified BuyerUS
The best Noot out there
Saw immediate effects and cerebral enhancements. Loved it. Reordering every 3-4 months
12/14/2023
Cosmic Nootropic
Dear Joseph, we're thrilled to know Cortexin is working for you. Thanks for being our loyal customer!
11/02/2023
Kai N.
Verified BuyerGB
It’s very good product. I feel clearly mind and have more concentration.
11/03/2023
Cosmic Nootropic
Hi Kai! We are glad that the product worked for you!
10/02/2023
henry b.
Verified BuyerCA
cortexin
cortexin really did help with my thinking.i will start another course in Nov.loved it
10/03/2023
Cosmic Nootropic
Dear Henry, thank you for sharing your experience with our product. We are glad that it helps you!
08/02/2023
Kandace M.
Verified BuyerUS
Amazing product
I love using Cortexin. It relieves my stress and anxiety almost immediately and it helps with concentration and focus. I keep this in my arsenal of peptides and bioregulators.
08/02/2023
Cosmic Nootropic
Hi Kandace, thank you for the review! We're glad that you're satisfied with the product. :)
06/05/2023
Dmitri S.
Verified BuyerUS
Great service
All expectations satisfied!
06/07/2023
Cosmic Nootropic
Hi Dmitri, thank you for your feedback! We're happy to hear that we met your expectations! :)
05/16/2023
Jennifer M.
Verified BuyerUS
Great Product Like Always
I really liked cortexin. Definitely something I will be alternating with Cerebro from here on.
05/19/2023
Cosmic Nootropic
Hi Jennifer, thank you for your feedback! We're thrilled to hear that you had a great experience with Cortexin.
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