Buy Encephabol in liquid or tablet form with 3–7 day fast domestic delivery within the US ($5) – just choose “Ships from: US (+15%)”
Encephabol (Pyritinol) is a cholinergic nootropic drug that is used to restore impaired cognitive functions and treat dementia.
By its chemical structure, Pyritinol is a vitamin B6 derivative that is obtained by bonding two molecules of pyridoxine with a disulfide bridge. However, the pharmacological action of Encephabol differs from that of Vitamin B6.
The drug was developed in 1961 by Merck (Germany) and has a long history of clinical use. As of today, Encephabol is marketed in more than 50 countries worldwide. It is used in medicine to treat dementia, decreased mental capacity, and developmental delays in children, such as autism.
Pyritinol does not produce a significant effect on aminergic systems, having practically no influence on levels, turnover, and uptake of dopamine, serotonin, GABA, and norepinephrine. Its main mechanism of action is cholinergic, antioxidant, and vasodilatory.
In studies, Pyritinol has been shown to:
- Increase blood ATP in a dose-dependent manner by up to 20%;
- Compensate the age-related reduction in glucose utilization by up to 75%;
- Increase choline uptake in striatal synaptosomes in both aged and young rats;
- Increase the cGMP content in the cortex by up to 50%;
- Produce a significant vasodilatory effect comparable to that of Vinpocetine;
- Produce vigilance-enhancing effects in EEG studies;
- Improve psychomotor performance and short-term memory in healthy volunteers.
To avoid possible side effects and potentiate the therapeutic action, it is highly recommended to take Pyritinol with an additional source of choline e.g. Cereton.
Encephabol and Vinpocetine have a synergistic effect on cerebral blood flow.
This product has not been approved by the US FDA. All statements on this page are for informational purposes only and have not been evaluated by the US FDA.
This product is not intended to diagnose, treat, cure, or prevent any disease. See more