Longidaza [Bovhyaluronidase Azoximer]

Clear
Bulk deal
Quantity Discount Discounted price
2 10% -
3 14% -
4 16% -
5 + 18% -
Bulk pricing will be applied to package:

Buy Longidaza (Longidaze) if you are looking for enzyme / anti-fibrotic supplement. It has a pathogenetic effect in inflammatory processes in the pelvic organs and in other diseases that lead to the development of fibrosis, the formation of adhesions and scars. The drug has a multicomponent action and has proven its efficacy both in complex and in monotherapy of various pathologies.

The Longidaza® drug is manufactured by the Russian pharmaceutical company NPO Petrovax Pharm in accordance with international and Russian GMP standards. The drug was introduced to the market in 2005 and is currently widely used in medical practice in Russia and other countries. In 2015, the World Health Organization (WHO) assigned the international non-proprietary name (INN) to the Longidaza® drug – bovhyaluronidase azoximer.

The drug consists of two components, which are connected to each other by conjugation:

  1. Enzyme hyaluronidase, which directly affects fibrosis and has a cleaving (proteolytic) effect;
  2. High molecular weight carrier that has an anti-inflammatory effect and allows the drug to be prescribed in the acute phase of the disease.

Longidaza® has a multicomponent action:

  • Reduces the risk of developing adhesions, changes the structure of adhesions, reducing their density and increases the woman’s chances of pregnancy;
  • Facilitates the delivery of antibacterial drugs and the permeability of tissues for these drugs directly to the inflammation focus, which increases the effectiveness of antibacterial treatment;
  • Improves microcirculation in tissues, which helps to reduce edema and to reabsorb hematomas;
  • Improves the effectiveness of the therapy of chronic prostatitis and reduces the frequency of exacerbations.

You can buy Longidaza for the following applications:

  1. GYNECOLOGY: treatment and prevention of adhesions in inflammatory diseases in the pelvic organs (endometriosis, salpingo-oophoritis, endometritis, etc.).
  2. UROLOGY: treatment and prevention of fibrosis in prostatitis, the initial stage of BPH / adenoma, interstitial cystitis, strictures of the urethra and ureters, Peyronie’s disease.
  3. COSMETOLOGY and DERMATOLOGY: treatment of fibrosis in limited scleroderma, hypertrophic and keloid cicatrixes and scars, etc.

In November 2018, Longidaza won the nomination of ‘Medication of Choice for the pathogenetic treatment of chronic prostatitis and relapse prevention’ at the Russian Pharma Awards.

Dosage and Administration:

Longidaza suppositories are recommended for rectal or vaginal administration once a day at night in a course of 10 to 20 intakes. The scheme of administration is adjusted depending on the severity, stage and duration of the disease. For the detailed information on administration please refer to the official instruction.

Side Effects:

Very rare: local reactions in the form of redness, edema, itching of the perianal zone, vaginal itching due to individual sensitivity to the components of the drug. If an allergic reaction develops discontinue the medicinal product and consult your doctor.

Contraindications:

The drug has contraindications. For more information please refer to the instruction.

Note:

The drug Longidaza has a potentiating effect, which means an increase in the effect on biologically active substances. In this connection, it is better to refrain from taking alcohol during the period of therapy.

Read full instruction here

References:

  1. Avdoshin VP et al (2013). Clinical efficacy of Longidaze for the prevention of cicatricial and sclerotic complications after surgery on the upper urinary tract. https://pubmed.ncbi.nlm.nih.gov/23789358/
  2. Pochernikov DG et al (2014). Experience in the treatment of autoimmune male infertility in patients with category 4 chronic prostatitis. https://pubmed.ncbi.nlm.nih.gov/25799732/
  3. Troshina NA et al (2015). Effect of Longidaze on Microbial Landscape of Cervical Canal and Uterine Cavity during Therapy of Women with Chronic Nonspecific Endometritis and Uterus Myoma. https://pubmed.ncbi.nlm.nih.gov/26470422/
  4. Fishchenko IV et al (2017). Diprospan, Longidaza and Their Combined Action against Fibrosis Caused By Mechanical Injury of the Intervertebral Discs in Rats. https://pubmed.ncbi.nlm.nih.gov/29975831/
  5. Kulchavenya EV et al (2018). Rationale of use and effectiveness of Longidaza in patients with chronic prostatitis. https://pubmed.ncbi.nlm.nih.gov/30761792/
  6. Neumark AI et al (2019). The influence of proteolytic enzymes on the antioxidant defensive system in infertile married men. https://pubmed.ncbi.nlm.nih.gov/31535808/
  7. Satybaldin DO et al (2019). Improvement of performance of semen culture in infertile men undergone to diagnostic evaluation. https://pubmed.ncbi.nlm.nih.gov/32003163/

Related products

CYTAMINS [NATURAL PEPTIDES]

$ 18.00$ 31.00

CYTAMINS are proteins, nucleoproteins and minerals isolated from organs of pigs and calves less than 12 months old. These peptide regulators are completely safe supplements that have been used for anti-ageing purposes and also as an aid to conventional treatment methods.

Caffeine is a substance that in its natural form is produced in the leaves and seeds of many plants. Caffeine stimulates the central nervous system, increases mental and physical performance, physical activity, shortens the reaction time, temporarily reduces fatigue and drowsiness, facilitates perception, increases heat production and urination, increases gastric secretion. It may be used as an extra energy source in the morning, as well as to stay productive during the day.

Arbidol [Umifenovir]

$ 26.00$ 50.00

Arbidol is a broad-spectrum antiviral compound developed in USSR in 1974. Arbidol demonstrates activity against a number of enveloped and non-enveloped viruses.В It is used for the prevention and treatment of influenza and other acute respiratory viral infections in adults and children.В Arbidol may also be immunomodulatory, and as such be capable of interferon induction and/or macrophage activation.

ACTOVEGIN ®

$ 27.00$ 69.00

Actovegin enhances aerobic oxidation, absorption of glucose and oxygen uptake in tissue. For this reason Actovegin has been used by athletes who wanted to speed up the recovery process and enhance physical performance and stamina. It is also a great drug to treat various sport injuries.

A perfect alternative for the discontinued Ladasten (Bromantane)