melarena-instruction
melarena-instruction

MELARENA ® (Melatonin)

Clear
Quantity
2
3
4
5
6
7
8 +
Discount
5%
8%
10%
12%
14%
16%
18%
Discounted price
-
-
-
-
-
-
-

Buy Melatonin with 37 day fast domestic delivery within the US ($5)  just choose “Ships from: US (+15%)”

Melarena (Melatonin) is an adaptogen, sedative and hypnotic drug based on a synthetic analog of the pineal hormone melatonin. It is used in case of jet lag, adjusts sleep-wake cycles in people whose daily work schedule changes (shift-work disorder), and helps blind people establish a day and night cycle. It stabilizes circadian rhythms.

It increases levels of gamma-Aminobutyric acid and serotonin in the midbrain and hypothalamus as it regulates the pyridoxal kinase which influences the synthesis of these compounds. The drug inhibits the secretion of gonadotropins and other pituitary gland hormones (corticotropin, thyroid-stimulating hormone, and somatotropin). It normalizes daily changes in body activity and temperature, improves brain activity, and reduces irritability. Melarena has a positive effect on night sleep. It helps fall asleep, reduces nighttime awakenings, and facilitates morning awakening.

The drug has also been proven effective in adapting to the rapid change of time zones while traveling. Buy Melarena (Melatonin) to reduce stress and weather sensitivity and stabilize the neuroendocrine system. Melarena has immunomodulating and antioxidant properties. The drug is non-addictive. It has been shown that the natural production of melatonin declines with age, so it is better to use melatonin at an older age.

We also sell Melatonin spray with passionflower extract under the brand name Good Sleep. Passionflower has natural sedative properties, reduces stress, and induces healthy sleep. Sublingual administration of the drug provides absorption that is 4 times faster than using melatonin tablets.

Melatonin is used in the prevention and treatment of:

  • Desynchronosis (alterations to the body’s circadian rhythms caused by rapid long-distance trans-meridian (east-west or west-east) travel or working shifts and jet lag);
  • Weather sensitivity;
  • Fatigue and sleep disorders;
  • Depression.

 

Produced by Stada / Nizhfarm, Russia.

Check out other adaptogens!


Legal Disclaimer
This product has not been approved by the US FDA. All statements on this page are for informational purposes only and have not been evaluated by the US FDA.
This product is not intended to diagnose, treat, cure, or prevent any disease. See more

Contents

Tablets

Coated tablets 0.3 mg and 3 mg.

Active ingredient: synthetic melatonin 0.3 or 3 mg;
Inactive ingredients: calcium hydrophosphate dihydrate 67.37 mg, microcrystalline cellulose 25 mg, sodium croscarmellose 2 mg, povidone K25 3.33 mg, fumed silica 0.5 mg, talc 1 mg, calcium stearate 0.5 mg.

Good Sleep spray

Distilled water, passionflower liquid extract 1: 5 (solvent water), melatonin. Each dose is 20 mg of Passiflora incamata liquid extract and 1.95 mg of Melatonin

Dosage and administration

Tablets

To be administered orally. The dosage is 1 tablet daily 30–40 minutes before sleep. Duration of treatment course is to be prescribed by a doctor (6–8 weeks). If necessary, the treatment courses can be repeated.

The dose of 0.3 mg is sufficient in most cases.

Good Sleep spray

To be administered sublingually. Remove the spray cap. Spray the aerosol once under the tongue. Thus, 150 mg of the product is sprayed, which is one dose. Recommended dosage is one dose one time per day, 20 minutes before bedtime. Shake well before use. 30 ml of the preparation contains 200 daily doses.

Side effects

Allergic response, headache, nausea, vomiting, diarrhea, morning sleepiness, or edema.

Contraindications

Hypersensitivity to melatonin and other components of the drug, autoimmune diseases, lymphogranulomatosis, leukemia, lymphoma, myeloma, epilepsy, diabetes mellitus, chronic kidney failure and other kidney diseases, pregnancy, lactation, and children under 18 years of age.

Overdose

Cases of overdose are not registered.

Drug interaction

Melarena is incompatible with monoamine oxidase inhibitors, glucocorticoids, and cyclosporine.

It enhances the effect of CNS depressants and beta-blockers.

It is not recommended to co-administer Melarena with nonsteroidal anti-inflammatory and hormonal drugs.

Storage conditions

Keep out of the reach of children. Store in a dark place at a temperature not higher than 25°C (77°F).
Shelf life is 2 years.

Manufacturer

Stada / Nizhfarm, Russia.

  1. P Pevet (2002) Melatonin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181670/
  2. Malhotra et al (2004) The Therapeutic Potential of Melatonin: A Review of the Science https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1395802/
  3. Buscemi et al (2004) Melatonin for Treatment of Sleep Disorders: Summary
  4. https://www.ncbi.nlm.nih.gov/books/NBK11941/
  5. Pandi-Perumal et al (2006) Melatonin: Nature’s most versatile biological signal? https://www.ncbi.nlm.nih.gov/pubmed/16817850
  6. Ferracioli-Oda et al (2013) Meta-analysis: melatonin for the treatment of primary sleep disorders https://www.ncbi.nlm.nih.gov/pubmed/23691095
  7. I Kostoglou-Athanassiou (2013) Therapeutic applications of melatonin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593297/
  8. Costello et al (2014) The effectiveness of melatonin for promoting healthy sleep: a rapid evidence assessment of the literature https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273450/
  9. B Claustrat, J Leston (2015) Melatonin: Physiological effects in humans https://www.ncbi.nlm.nih.gov/pubmed/25908646
  10. Masters et al (2015) Melatonin, the Hormone of Darkness: From Sleep Promotion to Ebola Treatment https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334454/
  11. Tordjman et al (2017) Melatonin: Pharmacology, Functions and Therapeutic Benefits https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405617/
  12. Xie et al (2017) A review of sleep disorders and melatonin https://www.ncbi.nlm.nih.gov/pubmed/28460563
  13. Meng et al (2017) Dietary Sources and Bioactivities of Melatonin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409706/
  14. N Zisapel (2018) New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057895/
  15. Zwart et al (2018) Long-Term Melatonin Therapy for Adolescents and Young Adults with Chronic Sleep Onset Insomnia and Late Melatonin Onset: Evaluation of Sleep Quality, Chronotype, and Lifestyle Factors Compared to Age-Related Randomly Selected Population Cohorts https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872230/

Related products

Vinpocetine or ethyl apovincaminate improves blood flow to the brain and is used to treat cerebrovascular disorders such as strokes and atherosclerosis. The vasodilatory action of Vinpocetine is mediated by a smooth muscle relaxation and a decrease of blood viscosity. According to clinical trials and anecdotal experiences, the drug can also be used to relieve tinnitus.

Befungin is a restorative and regenerative medicine based on Chaga mushroom. This preparation stimulates metabolism, restores hematogenesis and strengthens immune system after long-term illnesses.В Befungin contains the extract of a cinder conk (Chaga mushroom which grows on birch trees) with salts of 1.5% cobalt sulphate or 1% cobalt chloride.

Aralia is a well-known gentle adaptogenic tonic herb popular for its wide range of pharmacological properties. It is used to treat physical and mental fatigue, asthenic syndrome, arterial hypotension, decreased sex drive, mental breakdown, depression, enuresis, radiation sickness and metabolic disorders. ThisВ herbal remedy can also help to recover from craniocerebral injury, contusion, meningitis, post-infectious arachnoiditis and ARVI (in the complex therapy).

Afobazole® is an anxiolytic drug with nootropic properties that is available OTC in Russia and CIS countries. It stabilises and upregulates GABA and benzodiazepine receptors, exhibits neuroprotective properties, and diminishes anxiety and tensions in the body. Unlike benzos Afobazole does not have sedative, hypnotic, and muscle relaxant action. Fast US domestic shipping is available.