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MEMOPROVE ® (N-Pep-12)

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Memoprove is a dietary supplement that consists of a blend of neuropeptides N-Pep-12. It is designed to improve cognitive performance. Memoprove acts similarly to regulatory proteins of the nervous tissue that determine the division, differentiation, and survival of neurons.

It improves neuroplasticity and stimulates neuroprotection. Some even call them “Cerebrolysin pills”.


Synonyms N-Pep-12
Form: 30 pills of 425mg
Form description: Film-coated tablets
Active ingredient: N-Pep-12
Excipients: Lactose monohydrate
ATC code: V06B
Pharmacological action: Neuroprotective
Shelf life: 3 years. Do not use it beyond the expiration date printed on the package.
Storage conditions: Store in a dry dark place at temperatures no higher than 25°C (77°F). Keep out of reach of children.
Terms of release: Over-the-counter
Manufacturer: Klocke Pharma-Service, Germany / EVER Pharma, Austria


What is Memoprove?

The active substance of Memoprove is a mixture of N-Pep-12 neuropeptides which are extracted from the pig brain. Memoprove is designed to improve cognitive performance. 

This mixture of neuropeptides is obtained by enzymatic hydrolysis of purified proteins of nerve cells in compliance with all the GMP standards, using technologies approved by representatives of the European healthcare system.

The composition of Memoprove is very similar to Cerebrolysin. Some even call the preparation “Cerebrolysin pills“. Although it is less potent compared to Cerebrolysin peptides. 

Memoprove efficacy is confirmed by preclinical studies, as well as by the results of placebo-controlled studies in groups of volunteers [4, 5]. Memoprove has a favorable safety profile. There were no statistically significant differences in the incidence of adverse events between the groups receiving N-Pep-12 and placebo [8].

What are the Mechanisms of Action of Memoprove (N-pep-12)?

The effects of Memoprove are defined by these two mechanisms:

  • Stimulation of neuroplasticity – the formation of new interneuronal connections and regenerative processes leading to an improvement in cognitive functions such as attention, memory alertness and concentration;
  • Stimulation of neuroprotection – protection of neurons and connections between them to prevent damage to nerve cells due to exposure to adverse factors (stress, toxic substances from the environment, ischemia, etc.).

These mechanisms make it possible to reduce and prevent the general damaging effect of various factors on nerve cells and its consequences in the form of cognitive decline

What is Memoprove Used For?

Memoprove can be used in the following cases:

  • Mild to moderate memory impairments;
  • Short-term memory problems;
  • Age-related memory disorders;
  • Improvement of concentration, clarity, and mental alertness;
  • Facilitate processing large volumes of information, undergoing stress or overload at work;
  • Normalize sleep.

Where Can I Buy Memoprove  Online?

You can order Memoprove (N-Pep-12) online at different vendors. CosmicNootropic offers Memoprove in packs of 30x425mg pills. We offer fast US delivery and worldwide shipping with volume discounts! Always be sure to do your research before purchasing any nootropic supplement to ensure you are getting a quality product.

You can order Memoprove and get it delivered to the USA, Europe, the UK, Asia, and many other regions and countries via CosmicNootropic.

For more information on the analogs for cognitive improvement please refer to the post in our blog.

Legal Disclaimer
This product has not been approved by the US FDA. All statements on this page are for informational purposes only and have not been evaluated by the US FDA.
This product is not intended to diagnose, treat, cure, or prevent any disease. See more

What is Memoprove Dosage?

The dosage for adults is 1 pill per day, administered during a meal. The course duration is 1 month. If necessary, the course can be repeated after 1-2 months.


Individual intolerance to the components of the product, lactase deficiency, pregnancy and breastfeeding. Consult your doctor before use.

Safety of Use

Memoprove does NOT contain caffeine or other psychostimulants, herbs, yeast, dairy products, artificial colors, sugar, or preservatives. Memoprove has NO drug or food interactions.
  1. Buchwald D et al (1996). Functional status in patients with chronic fatigue syndrome, other fatiguing illnesses, and healthy individuals.
  2. Alvarez AX et al (1997). Citicoline improves memory in elderly subjects.
  3. Grundman M et al (2004). Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials.
  4. Volc D, Alvarez XA, Moessler H (2005). Cognitive Effects of the Novel Neuroprotective Dietary Supplement N-PEP-12: Evidence from a Self-Assessment Study.
  5. Windisch M et al (2005). N-PEP-12™ - a novel peptide compound that protects cortical neurons in culture against different age and disease associated lesions.
  6. Alvarez AX et al (2005). Neuropeptide dietary supplement N-PEP-12 enhances cognitive function and activates brain bioelectrical activity in healthy elderly subjects.
  7. Moessler H et al (2005). N-PEP-12 – a novel peptide compound that protects cortical neurons in culture against different age and disease associated lesions.
  8. Crook TH et al (2005). Effects of N-PEP-12 on memory among older adults.
  9. Matthews FE et al (2008). Two-year progression from mild cognitive impairment to dementia: to what extent do different definitions agree?
  10. Rodríguez-Sánchez E et al (2011). Prevalence of cognitive impairment in individuals aged over 65 in an urban area: DERIVA study.
  11. Nedrow A, Steckler N, Hardman J (2013). Physician Resilience and Burnout: Can You Make the Switch?
  12. Hutter-Paier B et al (2015). Long-term treatment of aged Long Evans rats with a dietary supplement containing neuroprotective peptides (N-PEP-12™) to prevent brain aging: effects of three months daily treatment by oral gavage.
  13. Shaffer J (2016). Neuroplasticity and Clinical Practice: Building Brain Power for Health.
  14. Roohi-Azizi M et al (2017). Changes of the brain’s bioelectrical activity in cognition, consciousness, and some mental disorders.
  15. Termine C et al (2018). Cognitive Impairment in Children and Adolescents with Migraine.
  16. Balea et al (2021) Effects of N-Pep-12 dietary supplementation on neurorecovery after ischemic stroke

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