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NEUROBION ® (Vitamins B1, B6, B12)

1 Reviews

Legal Disclaimer

All statements on this page are for informational purposes only and have not been evaluated by the US FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Before using this product, consulting a qualified MD is mandatory. See more

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Buy Neurobion Online!

Form: 3 vials of 3ml / 20 pills
Form description: Solution for intramuscular injection, red in color, transparent. / Tablets, coated with almost white shell, round, biconvex, glossy, with a faint characteristic odor.
Active ingredient: Pyridoxine, cyanocobalamin, thiamine
Excipients for vials: Potassium cyanide – 0.1 mg, sodium hydroxide solution 1M – 73 mg, water for injection – up to 3 ml.
Excipients for pills: Excipients: magnesium stearate, methylcellulose, sodium carboxymethyl starch, gelatin, mannitol, talc, glycerol 85%, colloidal silicon dioxide, purified water.

Coating composition: glyceryl monostearate wax, gelatin, methylcellulose, acacia gum, glycerol 85%, povidone K-25, calcium carbonate, colloidal silicon dioxide, kaolin, titanium dioxide, talc, sucrose.

ATC code: A11DB
Pharmacological action: Complex of B vitamins
Shelf life: 3 years. Do not use it beyond the expiration date printed on the package.
Storage conditions: Store in a dry dark place at temperatures up to 25°C (77°F). Keep out of reach of children.
Manufacturer: Merck, Austria / Dr. Reddy’s Laboratories, India.

What is Neurobion?

Neurobion is a complex of group B vitamins – Vitamin B1, Vitamin B6, and Vitamin B12. These are water-soluble vitamins that play an important part in the neurological processes of the CNS (Central Nervous System).

Neurobion comes in 2 forms: pills and injections.

Intended uses

In the comprehensive treatment of the following neurological conditions:
  • Neuritis and neuralgia (trigeminal neuralgia, facial nerve neuritis, intercostal neuralgia);
  • Pain syndromes caused by spinal disorders (lumbosciatica, plexopathy, radicular syndrome due to degenerative spinal changes).

Where to buy Neurobion?

Neurobion pills and injections are available to purchase online at CosmicNootropic with worldwide shipment. Always be sure to do your research before purchasing any nootropic supplement to ensure you are getting a quality product.

Check out other products from the Anti-Aging & Regeneration category!

How to use Neurobion

Pills

Take orally, without chewing, with a small amount of water, during or after meals.

1 pill 3 times a day or as prescribed by a doctor.

The duration of treatment is determined by the doctor and typically lasts 1-1.5 months. Adjusting the dosage of the medication is recommended for therapies lasting longer than 4 weeks.

Injections

The medication is administered intramuscularly (deep injections into the gluteal muscle).

Treatment is recommended to start with intramuscular injection of 1 ampoule (3 mL) daily until acute symptoms subside.

After improvement of symptoms or in cases of moderate severity: one ampoule 1-3 times per week for 2-3 weeks.

For maintenance therapy, to prevent recurrence or to continue the ongoing treatment course, Neurobion® in another dosage form (pills) is recommended.

The duration of treatment is determined by the doctor. Treatment for more than 4 weeks is not recommended.

Contraindications

– Increased sensitivity to any component of the medication;
– Inherited intolerance to galactose or fructose, lactase deficiency, glucose-galactose malabsorption, or sucrase-isomaltase insufficiency (the medication contains lactose and sucrose);
– Age under 18 years (due to the high content of active ingredients).

Use during pregnancy and breastfeeding:

The use of Neurobion® during pregnancy and lactation is not recommended due to its high vitamin content.

Vitamins B1, B6, and B12 are excreted in breast milk; however, the risk of overdose in newborns is not established. In isolated cases, high doses of vitamin B6 (>600 mg per day) may suppress lactation. If the medication is necessary during breastfeeding, breastfeeding should be discontinued.

Side effects

Frequency of adverse effects: very common (≥1/10), common (≥1/100, <1/10), uncommon (≥1/1000, <1/100), rare (≥1/10000, <1/1000), very rare (<1/10000, including isolated reports), frequency not established (frequency cannot be estimated from available data).

From the nervous system: frequency not established – prolonged use (>6-12 months) of vitamin B6 at a daily dose >50 mg may cause peripheral sensory neuropathy.

From the digestive system: frequency not established – nausea, vomiting, diarrhea, abdominal pain.

From the immune system: very rare – hypersensitivity reactions such as sweating, tachycardia.

Allergic reactions: very rare – skin reactions (itching, hives), anaphylactic shock.

General reactions and injection site disorders: frequency not established – reactions at the injection site.


Additional information about dosage, administration, and ingredients can be found on the packaging.

  1. Fu et al (1988) B vitamins suppress spinal dorsal horn nociceptive neurons in the cat https://www.ncbi.nlm.nih.gov/pubmed/3226608
  2. D Bonke, B Nickel (1989) Improvement of fine motoric movement control by elevated dosages of vitamin B1, B6, and B12 in target shooting https://www.ncbi.nlm.nih.gov/pubmed/2507698
  3. Dakshinamurti et al (1990) Influence of B vitamins on binding properties of serotonin receptors in the CNS of rats https://www.ncbi.nlm.nih.gov/pubmed/2157087
  4. Jurna et al (1990) Acute effects of vitamin B6 and fixed combinations of vitamin B1, B6 and B12 on nociceptive activity evoked in the rat thalamus: dose-response relationship and combinations with morphine and paracetamol https://www.ncbi.nlm.nih.gov/pubmed/2157085
  5. Magana-Villa (2013) B-vitamin mixture improves the analgesic effect of diclofenac in patients with osteoarthritis: a double blind study https://www.ncbi.nlm.nih.gov/pubmed/23526240
  6. Syed et al (2013) Vitamin B12 Supplementation in Treating Major Depressive Disorder: A Randomized Controlled Trial https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856388/
  7. L Shen et al (2015) Associations between B Vitamins and Parkinson’s Disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586528/
  8. Dong et al (2015) Efficacy of Supplementation with B Vitamins for Stroke Prevention: A Network Meta-Analysis of Randomized Controlled Trials https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565665/
  9. Kamchatnov et al (2015) The use of neurobion in neurological practice https://www.ncbi.nlm.nih.gov/pubmed/26525818
  10. B Jayabalan, L Low (2016) Vitamin B supplementation for diabetic peripheral neuropathy https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759374/
  11. Rathod et al (2016) Novel insights into the effect of vitamin B12 and omega-3 fatty acids on brain function https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727338/
  12. Ebrahimi et al (2018) Effect of vitamins B1, B6, and B12 (Neurobion) on Diisopropylfluorophosphate–induced Delayed Neuropathy in Mice https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094411/
  13. Togha et al (2020) Suppression of Menstrual-Related Migraine Attack Severity Using Pyridoxine, Thiamine, and Cyanocobalamin: A Quasi-Experimental Within-Subject Design https://www.researchgate.net/publication/341831464 
  14. S Baltrusch (2021) The Role of Neurotropic B Vitamins in Nerve Regeneration https://pubmed.ncbi.nlm.nih.gov/34337067/
  15. H Nguyen, M-S Kim (2022) The role of mixed B vitamin intakes on cognitive performance: Modeling, genes and miRNAs involved https://pubmed.ncbi.nlm.nih.gov/35714552/
  16. Paez-Hurtado et al (2023) Mechanisms of action of vitamin B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin) in pain: a narrative review https://pubmed.ncbi.nlm.nih.gov/35156556/

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05/02/2024

Lyudmyla U.

Lyudmyla U.

 Verified Buyer
CA

CA

It took forever to get it, but it is finally arrived

My parcel sit on Canadian border for two months. But it is finally here.Not fault of the company but I would of prefer to receive it when I ordered.Now I will have to wait for the fall to have a treatment cycle.

05/02/2024

Hi Lyudmyla! We're so sorry to hear this. We will definitely look into this issue to see if there's anything we can do to not let this happen again.

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