Persen [Pepermint, Lemon balm, Rhizome]

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Persen is a sedative and antispasmodic herbal drug.

It is used to treat neurosis accompanied by stress, impaired attention, anxiety and insomnia that are usually treated with potent therapy.

It can also be used as a replacement therapy after the withdrawal of strong sedatives. Persen can be prescribed for the prevention of psychosomatic disorders caused by stress. It has also proved to be effective in dysautonomia treatment.

Pharmacodynamic properties

Valerian root and rhizome extract has a calming effect.

Lemon balm leaf extract has a soothing and antispasmodic effect.

Peppermint leaf extract has antispasmodic and moderate sedative effects.


  • increased nervous irritability and excitability;
  • insomnia;
  • as a part of a complex therapy of dysautonomia.

Manufactured by Sandoz


One coated tablet contains the following ingredients:
  • 50 mg of dry extract of medicinal valerian rhizomes with roots (corresponds to 35 mg of the native extract);
  • 25 mg of dry extract of lemon balm leaves (corresponds to 17.5 mg of the native extract);
  • 2 mg of dry peppermint leaf extract (corresponds to 15.5 mg of the native extract);
  • inactive ingredients: talc, magnesium stearate, crospovidone, corn starch, silica, lactose and sucrose.
Dosage and Administration To be administered orally, independent of meals. Dosage for adults and children over 12 years of age: 2-3 tablets 2-3 times a day. Side effects Allergic response or bronchospasm. The prolonged drug administration can cause constipation. Counterindications:
  • hypersensitivity to the components of the drug;
  • lactose intolerance, lactose deficiency or glucose galactose malabsorption;
  • sucrase/isomaltase deficiency or fructose intolerance;
  • arterial hypotension;
  • cholangitis or biliary disease;
  • pregnancy and lactation;
  • children under 12 years of age.
Drug interaction Persen enhances the effect of hypnotic drugs and other CNS depressants, antihypertensive drugs and painkillers, thus requiring the dosage adjustment. Overdose Overdose can cause fatigue, abdominal pain, dizziness, dilated pupils, chest pain or shaking hands. If the symptoms do not disappear on their own within 24 hours, perform a gastric lavage and consult a doctor. Storage conditions Store at a temperature not higher than 25 °C (77 °F). Keep out of the reach of children. Manufacturer Sandoz Pharmaceuticals d.d., Slovenia

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