Dosage and administration

The most common dosages are 250-500 mg 2 - 3 times a day. The maximum single dosage is 750 mg. The usual course duration is 2 - 3 weeks.

Side effects 

In general, side effects are rare. (<10%) They might occur in the beginning of the treatment and they include increase in irritability, lethargy, dizziness, nausea and allergic reactions.


Pronounced lethargy, nausea, vomiting, fatty dystrophy of liver (when taken in excess of 7 grams), eosinophilia, low arterial blood pressure and kidney dysfunction.

Country of Manufacture: Russia/Latvia

You can read the full instruction here

US Domestic shipping is available for this product! Choose Ships from: US size option to get it in 3-7 days to any US address. Dont forget to choose US Domestic Shipping when checking out.

Phenibut produced by Organika has limited availability. We resort the right to ship Phenibut of the same quality produced by other Russian manufacturers. The package might be different from the one presented on the website!

US Domestic shipping is available for this product! Choose /US DOMESTIC SHIPPING/ size option to get it in 3-7 days to any US address.

Synthesized by professor V. Perekalin in 1959, Phenibut was quickly recognised as a very promising chemical compound, as it had both psychostimulating and anxiety reducing effects. After several years of research, Phenibut was added to the Russian astronauts' medical kit: it could decrease the stress of cosmonauts and also allow them to maintain the same performance level, unlike usual tranquillisers. It is a known fact that the cosmonauts of the Soyuz-Apollo Test Project had it in their medical kits. 

Phenibut is a derivative of the naturally occurring inhibitory neurotransmitter GABA, which can cross the blood-brain barrier much better than the original compound. Years of extensive research on humans revealed that Phenibut can be used to relieve the following symptoms:

  • Emotionally labile disorders
  • Asthenic disorders (lack of energy)
  • ADHD in children
  • Alcohol withdrawal
  • Poor sleep quality in older patients
  • Lack of motivation
  • Other conditions characterised by reduced intellectual productivity

One pack of Phenibut contains 20 pills, each with 250 mg of active ingredient, which is sufficient for approximately 5 - 10 days of administration.

Note: Phenibut is a completely safe medication when used in moderation. However, if taken in large quantities for recreational purposes, it is likely to cause tolerance and withdrawal symptoms. It has different effects when taken in high doses. Therefore, we limit the maximum order quantity to 4 packs of 20 pills.  

Phenibut is also used by athletes and bodybuilders, as it increases resting and post-exercise growth-hormone secretion.

Special things about Phenibut:

  • Instant anxiolytic effect.
  • Phenibut improves attention, memory, speed and accuracy unlike tranquillisers.
  • Improves motivation but might drain your willpower.
  • Small dosages have calming and nootropic effects, while larger ones have stimulating effect.

Country of Manufacture: Russia/Latvia

Legal Disclaimer

This product has not been approved by the US FDA. All statements on this page are for informational purposes only and have not been evaluated by the US FDA.

This product is not intended to diagnose, treat, cure, or prevent any disease.

  1. I Lapin (2001) Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug
  2. G Shul'gina, E Ziablitseva (2005) Effect of the GABA derivative phenibut on learning
  3. E Ziablitseva, I Pavlova (2007) Effect of GABA receptor agonist phenibut on behavior and respiration of rabbits in the negative emotional situation
  4. E Zyablitseva, I Pavlova (2008) Effects of the GABA receptor agonist phenibut on behavior and respiration in rabbits in emotionally negative situations
  5. Dambrova et al (2008) Comparative pharmacological activity of optical isomers of phenibut
  6. Ziablitseva et al (2009) The effects of agonists of ionotropic GABA(A) and metabotropic GABA(B) receptors on learning
  7. E Ziablitseva, I Pavlova (2009) Influence of GABA agonist phenibut on the neuronal activity and interaction in hippocampus and neocortex in emotionally negative situations
  8. Borodkina et al (2009) Effect of phenibut on the content of monoamines, their metabolites, and neurotransmitter amino acids in rat brain structures
  9. Tiurenkov et al (2012) Fenibut and its citrate prevent psychoneurological disorders caused by chronic stress (paradoxical sleep deprivation)
  10. Samokhvalov et al (2013) Phenibut dependence
  11. Owen et al (2016) Phenibut (4-amino-3-phenyl-butyric acid): Availability, prevalence of use, desired effects and acute toxicity
  12. Volotova et al (2016) Neuroprotective action of phenibut and neuroglutam in experimental cerebral ischemia on the background of altered immunoreactivity
  13. Vavers et al (2016) The neuroprotective effects of R-phenibut after focal cerebral ischemia
  14. Ahuja et al (2018) Phenibut (β-Phenyl-γ-aminobutyric Acid) Dependence and Management of Withdrawal: Emerging Nootropics of Abuse
  15. Joshi et al (2018) Dissociative intoxication and prolonged withdrawal associated with phenibut: a case report

Type: Nootropics