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PICAMILON ® (Nicotinoyl-GABA)
36 Reviews
Description
Dosage
Research
Reviews
Picamilon Information
| INN: | N-nicotinoyl-gamma-aminobutyric acid |
| Chemical name of Picamilon: | Sodium salt of N-nicotinoyl-g-aminobutyric acid |
| Form: | Pills (20 mg and 50 mg) |
| Active ingredient: | Picamilon or N-nicotinoyl-GABA – 20mg or 50 mg |
| Excipients: | Potato starch, magnesium hydroxycarbonate hydrate, talc, sucrose, stearic acid or calcium stearate. |
| CAS Number: | 34562-97-5 |
| Molecular formula: | C10H12N2O3 |
| ATC code: | N06BX Nootropic |
| Pharmacological action: | Tranquilizing, psycho-stimulating, antiaggregant, antioxidant |
| Bioavailability: | From 50 to 88% |
| Half-life: | 30 min |
| Shelf life: | 3 years. Do not use beyond the expiration date printed on the package. |
| Storage conditions: | Store in a dry dark place at temperatures no higher than 25°C (77°F). Keep out of reach of children. |
| Manufacturer: | PharmStandard, https://pharmstd.com/ |
What is Picamilon?
Picamilon Sodium (Pikamilon) is a nootropic compound that was synthesized in the USSR in the middle of the 1960s to support brain health and help with anxiety and insomnia. And it has been used as a treatment for neurological problems since then.
Picamilon is based on a synthetic combination of GABA and niacin. This unique blend has been shown to have a variety of benefits for the mind and body. Some of these benefits include improved mood, better brain function, protection against Alzheimer’s disease, and regulation of cerebral blood flow.
Gamma-aminobutyric acid (or GABA) in Picamilon is responsible for reducing neuronal excitability. And niacin acts as a strong vasodilator.
What is Picamilon Used For?
Buy Picamilon to treat the following symptoms and conditions:
- Cerebrovascular diseases;
- Migraine;
- Asthenic disorders (lack of energy);
- Depressions;
- Alcohol withdrawal syndrome.
A well-known biohacker Lucas Aoun reviews Picamilon on YouTube – click below:
As the official instruction claims, Picamilon dilates blood vessels in the brain. It also has tranquilizing, psychostimulating, antiaggregant, and antioxidant effects. Picamilon nootropic improves the functional state of the brain due to the normalization of tissue metabolism and its influence on cerebral circulation. It increases the volume and linear speed of cerebral blood flow, reduces the resistance of cerebral vessels, suppresses platelet aggregation, and improves microcirculation.
After a full treatment course, Picamilon increases physical and mental efficiency, reduces headaches, improves memory, and normalizes sleep. It contributes to the reduction or disappearance of anxiety, tension, and fear. The drug also improves the condition of patients with motor and speech disorders.
Where to Buy Picamilon?
Although it is not a verified dietary supplement in the USA, consumers can easily buy Picamilon online. If you want to purchase Picamilon, buy it at CosmicNootropic. It’s a reliable vendor that offers high-quality nootropics and supplements to improve brain function, reduce anxiety and enhance general well-being.
Legal Disclaimer
All statements on this page are for informational purposes only and have not been evaluated by the US FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Before using Picamilon consulting a qualified MD is mandatory. See more
Picamilon Dosage
Dosages of Picamilon vary depending on the condition. That being said, the typical daily Picamilon dose is 30–50 mg, once or twice a day. To learn more about the Picamilon dosage please read the official instructions below.
One pack of Picamilon contains 30 pills, each with 30 or 50 mg of the active ingredient. One pack is sufficient for approximately 15–30 days of administration.
Picamilon Safety
As with human consumption of any new supplement, it is important to do your research before taking Picamilon. Be sure to consult with a healthcare professional if you have any questions or concerns about its use.
Picamilon Side effects
Side effects occur in approximately 12% of patients and are characterized by moderate headaches, insomnia, fatigue, and allergic reactions.
Сonsuming too much Picamilon may result in an increase of potential side effects.
Picamilon vs Phenibut: What’s the Difference?
Picamilon is an “older brother” of Phenibut. Picamilon and Phenibut are two substances that are often confused with each other. They have similar properties. However, they are not the same.
Both drugs reduce anxiety and improve mood. However, unlike Phenibut, Picamilon is said to have a much stronger impact on energy metabolism in the brain because it stimulates the consumption of oxygen and glucose by the neuronal tissue.
Similar to Phenibut, Picamilon should be taken for a maximum period of 3 weeks. And it has the capacity to cause withdrawal syndrome if abused.
OFFICIAL INSTRUCTION of Picamilon
- Voznesenskii et al (1989) Comparative study of the effect of picamilone and piracetam on learning in rats in a radial maze https://www.unboundmedicine.com/medline/citation/2806520/
- I Sapegin, A Beketov (1993) The effect of pikamilon and fenibut on the blood supply of the brain at rest and under gravitational exposures https://www.ncbi.nlm.nih.gov/pubmed/8324468
- Shyman’kyi et al (2002) Oxidative stress correction by nicotinamide and nicotynol-GABA in diabetic neuropathy https://www.ncbi.nlm.nih.gov/pubmed/12916162
- Kuchmerovs’ka et al (2003) State of GABA-benzodiazepine receptor complex in diabetic neuropathy: effect of nicotinamide and nicotinoyl-GABA https://www.ncbi.nlm.nih.gov/pubmed/14577176
- Silkina et al (2005) Gabaergic mechanism of cerebrovascular and neuroprotective effects of afobazole and picamilon https://www.ncbi.nlm.nih.gov/pubmed/15786959
- Likhodeev et al (2009) Effects of aminalon, fenibut, and picamilon on the typological parameters of cerebral hemodynamics in swimmers with dysadaptation syndrome https://www.ncbi.nlm.nih.gov/pubmed/19803364
- Avula et al (2016) Identification and quantification of vinpocetine and picamilon in dietary supplements sold in the United States https://www.ncbi.nlm.nih.gov/pubmed/26426301
- Zakharov et al (2022) [Treatment of patients with chronic cerebral ischemia: experience of using the combined neuroprotective drug Picamilon Ginkgo] https://pubmed.ncbi.nlm.nih.gov/36168693/
- M Santillo, R Sprando (2023) Picamilon, a γ-aminobutyric acid (GABA) analogue and marketed nootropic, is inactive against 50 biological targets https://pubmed.ncbi.nlm.nih.gov/36668678/
4.3
Based on 36 Reviews
(25)
(2)
(5)
(1)
(3)
11/05/2023
K. M.
Verified Buyer
US
Really works!
Interesting pill. Taking less doesn't make me feel much, but if I take one or two 50mg, after I awake it gives me slight energy and relieves anxiety. I was have some issues with anxiety, and when I take these, plus sometimes pregabalin (I am prescribed it from my doc), I feel fine. I don't overdue it though, and make sure I leave at least 3 hours after taking it before I have a drink. At any rate, this is very subtle yet effective. I am ordering more.
11/05/2023
Thanks for the detailed feedback! We're glad Picamilon works well for you ☺️
11/02/2023
Jared S.
Verified Buyer
CA
Super Calming
Super relaxing, great sleep on this. Definitely boosts the effects of other tranquilizing Or stimulating nootropics in a way. My anxious partner loves it for studying, helps her focus.
11/03/2023
Dear Jared, we're glad to hear that Picamilon has had a positive impact on your and your partner's life!
10/22/2023
Kelly L.
Verified Buyer
US
Excellent supplement
Great product. I will be buying again. Really helps with restless legs or issues sleeping. Lowers anxiety at night and has a nice sedative effect. And unlike alcohol, I don't believe that this effects sleep in a negative way... as far as I can tell, it makes it better.
10/25/2023
Dear Kelly, thank you for sharing your experience, we are glad you are satisfied with our product!
09/08/2023
Martin
Verified Buyer
US
Less is more
Oddly, I experience a pronounced anxiolytic and relaxing effect if I take a quarter of one tablet. When I tried taking a whole one, I didn\'t feel anything. Can\'t explain it, but that\'s how it works for me.
09/08/2023
Hi Martin! We're glad the product works for you! For most nootropics, the effect can be varied for different people and sometimes for the same person in different situations. It always depends on many conditions.
08/23/2023
Sasho
Verified Buyer
US
Great
I love the whole experience of shopping with Cosmic Nootropic.Product of great quality.You got a loyal customer in me.
08/25/2023
Dear Sasho, thank you for your feedback! We really appreciate it!
08/23/2023
Sasho
Verified Buyer
US
Positive
Really satisfied with the whole experience of shopping with CosmicNootropic and high quality product
08/25/2023
Dear Sasho, thank you for your feedback! We really appreciate it!
07/12/2023
Matt B.
Verified Buyer
US
Great
Wish it came in larger bottle, already need more.
07/13/2023
Hi Matt! Thank you for the feedback on the product. We're happy to know that you like it!
05/22/2023
Desh P.
Verified Buyer
US
Bad
Bad didn’t do **** to me
05/24/2023
Hi Desh, I'm sorry that the product didn't work for you. 😔 For most nootropics, the effect can be varied for different people. It strongly depends on personal conditions, so we always recommend consulting a specialist before taking any medication.
05/10/2023
Daniel H.
Verified Buyer
GB
Item not received
Item not received
05/10/2023
Hi Daniel, I'm sorry that you didn't receive the product, but I see that we have already refunded your money for it. Please let us know via email if you need any additional help!
04/22/2023
Charles G.
Verified Buyer
US
Great Product - Fast shipping from inside US now.
Love this stuff and Love CosmicNootropics
04/28/2023
Thank you, Charles! We are very happy to hear that! 🧡
03/20/2023
Garret L.
Verified Buyer
US
They seem to work!
I usually like to take 300mg at once, I find it has the best effect at the dose for me, definitely mellows you out and reduces mental chatter and anxiety without making you too drowsy. Will be buying again!
03/20/2023
Thank you very much for this helpful review, Garrett!
02/15/2023
Cat R.
Verified Buyer
US
Picamilon to dissolve anxiety/stress; from an honest merchant.
My own experience with Picamilon has been that it quietly and unobstrusively appears to dissolve my anxiety/stress without any other effect such as sleepiness or, worse, making me “high” as I am not interested in getting high but only in calming the anxiety/stress caused by my severe, chronic pain. Unfortunately, it does not address my pain, but I am grateful that it lessens my anxiety/stress. I am not a medical professional. However, I feel it a shame that American psychiatrists do not offer picamilon as a first line against anxiety/stress and, instead, opt for drugs that may have dangerous side-effects and/or risk of tolerance/abuse. Lastly, CosmicNootropic.com has always dealt honestly with me and that is a great comfort as well.
02/17/2023
Hi Cat! Thank you for your feedback, really appreciate it 💛We are glad that our product helps you!
01/12/2023
Chris S.
Verified Buyer
US
Helpful
I still have 3 1/2 bottles left. It appeared to be helpful but none of the bottles are sealed. I questioned that and was told that’s how they come and it’s nothing to worry about. It could’ve been Tylenol for all I know but it did seem to help calm me for the short time I used it.
01/14/2023
Hi Chris! We are glad that the product helped you. Picamilon bottles are always just packed in the box and has no inner or outer safety seal. If you still have doubts, we are here for you!
12/31/2022
Blaine R.
Verified Buyer
US
Very very weak effects
There’s a reason this drug never caught much wind. I would rate this weaker than L-theanine on the anxiolytic spectrum.
01/04/2023
Hi Blaine! Thanks for sharing your experience! I'm sorry that the product didn't work for you. :( For most nootropics, the effect can be varied for different people. It strongly depends on the personal conditions, so we always recommend consulting a specialist before taking any medication.
09/04/2022
Gleb S.
Verified Buyer
US
A+
Order received quickly
05/14/2022
Charles G.
Verified Buyer
US
This stuff really works for anxiety!
I have been using CosmicNootropic's Picamilon for a number of years now and have always been happy with the quality and effectiveness of their products. And, very cool that they have managed to remain open and able to accept payments during the current troubles in Ukraine.
08/01/2022
Hi Charles, Thank you for your feedback, we really appreciate it! 😊
04/17/2022
Thomas O.
Verified Buyer
US
Helped alot with my anxiety and didnt make me feel ***** like some other an iety meds do
Excellent product!worked perfectly!
08/03/2022
Hi Thomas, Thank you very much for your feedback!
02/25/2022
Charles G.
Verified Buyer
US
Picamilon is some great stuff !!!
For most of my adult life I have suffered from social anxiety but that all changed when I found the Russian discovered supplement Picamilon. Works in as little as 20 minutes! You can actually feel the anxiety melt away. Very Cool. So if I am going to buy a Russian discovered supplement why not buy it from a Russian source, eh? Cosmicnootropic.com has always treated me very well, you will like them too.
12/25/2021
Charles G.
Verified Buyer
US
This Stuff really Works!!!
Hi All, Cosmic Nootropic Picamilon relieves my anxiety in as little as 30 minutes. Turns out I was GABA deficient and this fixes that like nothing else I have tried. For the more technical among you GABA supplementation alone will not increase GABA levels in your brain where the receptors are because GABA will not cross the blood-brain barrier by itself. However, if you bind GABA to Niacin (vitamin B3) then the combination can cross the blood-brain barrier whereupon the GABA is made available to the GABA receptors in our brains and anxiety is relieved. God Bless Cosmic Nootropic for making this supplement available to us!
10/30/2021
Vsevolod I.
Verified Buyer
BG
I do not know, but I believe in Russian products not less then I believe in American products. I was angry when the president Biden said that Putin is a killer. I beleive in Russia. Sincerely yours, Vsevolod Ivanov
Thank you!
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