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PICAMILON ® (Nicotinoyl-GABA)

65 Reviews

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$25.65 /item
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$25.11 /item
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$24.57 /item
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$24.03 /item
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$23.76 /item
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save 13%
$23.49 /item
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All statements on this page are for informational purposes only and have not been evaluated by the US FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Before using this product, consulting a qualified MD is mandatory. See more

Picamilon Information

INN: N-nicotinoyl-gamma-aminobutyric acid
Chemical name of Picamilon: Sodium salt of N-nicotinoyl-g-aminobutyric acid
Form: Pills (20 mg and 50 mg)
Active ingredient: Picamilon or N-nicotinoyl-GABA – 20mg or 50 mg
Excipients: Potato starch, magnesium hydroxycarbonate hydrate, talc, sucrose, stearic acid or calcium stearate.
CAS Number: 34562-97-5
Molecular formula: C10H12N2O3
ATC code: N06BX Nootropic
Pharmacological action: Tranquilizing, psycho-stimulating, antiaggregant, antioxidant
Bioavailability: From 50 to 88%
Half-life: 30 min
Shelf life: 3 years. Do not use beyond the expiration date printed on the package.
Storage conditions: Store in a dry dark place at temperatures no higher than 25°C (77°F). Keep out of reach of children.
Manufacturer: PharmStandard, https://pharmstd.com/

What is Picamilon?

Picamilon Sodium (Pikamilon) is a nootropic compound that was synthesized in the USSR in the middle of the 1960s to support brain health and help with anxiety and insomnia. And it has been used as a treatment for neurological problems since then.

Picamilon is based on a synthetic combination of GABA and niacin. Gamma-aminobutyric acid in Picamilon is responsible for reducing neuronal excitability. And niacin acts as a strong vasodilator.

This unique blend has been shown to have a variety of benefits for the mind and body. Some of these benefits include improved mood, better brain function, protection against Alzheimer’s disease, and regulation of cerebral blood flow.

What is Picamilon Used For?

  • Cerebrovascular diseases;
  • Anxiety;
  • Migraine;
  • Asthenic disorders (lack of energy);
  • Mild depressions;
  • Alcohol withdrawal syndrome.

Picamilon Safety Precaution

As with human consumption of any new supplement, it is important to do your research before taking Picamilon. Be sure to consult with a healthcare professional if you have any questions or health concerns.

A well-known biohacker Lucas Aoun reviews Picamilon on YouTube – click below

What are the Effects of Picamilon?

As the official instruction claims, Picamilon dilates blood vessels in the brain. [2] It also has tranquilizing, psychostimulating, antiaggregant, and antioxidant effects. Picamilon nootropic can improve the functional state of the brain due to the normalization of tissue metabolism and its influence on cerebral circulation. The listed effects include increased volume and linear speed of cerebral blood flow, reduced resistance of cerebral vessels, suppressed platelet aggregation, and better microcirculation.

After a full treatment course under the doctor’s supervision, Picamilon is said to increase physical and mental efficiency, reduce headaches, and normalize sleep. Anecdotal reports on Picamilon reddit say that it can contribute to the reduction of anxiety, tension, and fear.

Where to Buy Picamilon?

Although it is not a verified dietary supplement in the USA, consumers can easily buy Picamilon online. If you want to purchase Picamilon, buy it at CosmicNootropic. It’s a reliable vendor that offers high-quality nootropics and supplements to improve brain function, reduce anxiety and enhance general well-being.

Picamilon Dosage

Dosages of Picamilon and course duration depend on the patient’s condition and your doctor’s recommendations. The typical daily dose for pills is 30–50 mg, once or twice a day. Picamilon injection dosage varies from 100 to 200 mg once a day.

To learn more about the Picamilon dosage please read the official instructions below.

Picamilon Side effects

Side effects occur in approximately 12% of patients and are characterized by decreased blood pressure, dizziness, headache, mild nausea, irritability, agitation, anxiety, and allergic reactions (skin rash, itching).

Сonsuming too much Picamilon may increase potential side effects.

Picamilon vs Phenibut: What’s the Difference?

Picamilon is an “older brother” of Phenibut. They have similar properties, but they are not the same.

Both drugs reduce anxiety and improve mood. However, unlike Phenibut, Picamilon is said to have a much stronger impact on energy metabolism in the brain because it stimulates the consumption of oxygen and glucose by the neuronal tissue.

Like Phenibut, Picamilon shall not be taken for a period longer than 3 weeks. And both can cause withdrawal syndrome if abused.

OFFICIAL INSTRUCTION of Picamilon Pills

OFFICIAL INSTRUCTION of Picamilon Injections

  1. Voznesenskii et al (1989) Comparative study of the effect of picamilone and piracetam on learning in rats in a radial maze https://www.unboundmedicine.com/medline/citation/2806520/
  2. I Sapegin, A Beketov (1993) The effect of pikamilon and fenibut on the blood supply of the brain at rest and under gravitational exposures https://www.ncbi.nlm.nih.gov/pubmed/8324468
  3. Shyman’kyi et al (2002) Oxidative stress correction by nicotinamide and nicotynol-GABA in diabetic neuropathy https://www.ncbi.nlm.nih.gov/pubmed/12916162
  4. Kuchmerovs’ka et al (2003) State of GABA-benzodiazepine receptor complex in diabetic neuropathy: effect of nicotinamide and nicotinoyl-GABA https://www.ncbi.nlm.nih.gov/pubmed/14577176
  5. Silkina et al (2005) Gabaergic mechanism of cerebrovascular and neuroprotective effects of afobazole and picamilon https://www.ncbi.nlm.nih.gov/pubmed/15786959
  6. Likhodeev et al (2009) Effects of aminalon, fenibut, and picamilon on the typological parameters of cerebral hemodynamics in swimmers with dysadaptation syndrome https://www.ncbi.nlm.nih.gov/pubmed/19803364
  7. Avula et al (2016) Identification and quantification of vinpocetine and picamilon in dietary supplements sold in the United States https://www.ncbi.nlm.nih.gov/pubmed/26426301
  8. Zakharov et al (2022) Treatment of patients with chronic cerebral ischemia: experience of using the combined neuroprotective drug Picamilon Ginkgo https://pubmed.ncbi.nlm.nih.gov/36168693/ 
  9. M Santillo, R Sprando (2023) Picamilon, a γ-aminobutyric acid (GABA) analogue and marketed nootropic, is inactive against 50 biological targets https://pubmed.ncbi.nlm.nih.gov/36668678/ 

4.4

Based on 65 Reviews

(50)

(3)

(5)

(3)

(4)

 

11/11/2024

Heather W.

Heather W.

 Verified Buyer
US

US

Love it!

1 pill is perfect for mild relaxation. 2 are perfect for unwinding before bed. I have amazing sleep and wake up energized.

11/11/2024

Cosmic Nootropic

Dear Heather, thank you for sharing your experience! We're so happy to hear that you’re enjoying the effects—relaxation, great sleep, and waking up energized sound like the perfect combo. We appreciate your feedback and are glad our product is helping you unwind!

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09/26/2024

Benjamin P.

Benjamin P.

 Verified Buyer
US

US

Very helpful

Very helpful for getting off Kratom!

10/07/2024

Cosmic Nootropic

Dear Benjamin, Thank you for your kind words! We’re so glad to hear that our product have been helpful for you in your journey.

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09/20/2024

Alan Y.

Alan Y.

 Verified Buyer
SG

SG

Solid company and products

**Company Opinion** CosmicNootropic has truly impressed me with its exceptional customer service. Unlike many companies that provide generic responses, their team actively listens to my concerns and works diligently to resolve them. This personalized approach sets them apart in a crowded market. My overall experience with the brand has been outstanding; they prioritize customer satisfaction and demonstrate a genuine commitment to helping their clients. **Product Review** I purchased **Picamilon** and **Mexidol**, and I am delighted with both products. - **Picamilon** is known for its ability to enhance focus and calmness, making it an excellent choice for navigating the stresses of my work environment in procurement. It effectively boosts mental clarity while reducing anxiety, allowing me to maintain productivity without feeling overwhelmed. Users have reported improvements in mood, cognitive function, and even physical working capacity after stressful tasks, which resonates with my experience. - **Mexidol**, on the other hand, has been a game-changer for managing stress levels. It acts as an antioxidant that protects brain cells from damage while improving cognitive processes such as attention and memory. The product has helped me feel more resilient in high-pressure situations, aligning perfectly with its reputation for enhancing mental performance and emotional well-being. Both products have exceeded my expectations, providing me with the mental focus I need while keeping me calm under pressure. **Personal Experience** The ordering process with CosmicNootropic was seamless. The website is user-friendly, making it easy to navigate through product options and information. I encountered some technical issues during my purchase, but the customer service team was prompt and reassuring, ensuring that my concerns were addressed quickly. Upon delivery, I was satisfied with the packaging; everything arrived intact and well-protected. The delivery time was also impressive, as my order arrived within the expected timeframe. Overall, my experience with CosmicNootropic has been overwhelmingly positive, making them a reliable source for nootropic products.

09/23/2024

Cosmic Nootropic

Thank you so much for sharing your detailed experience, Alan! We're thrilled to hear that both Picamilon and Mexidol have been working so well for you, and that our customer service was able to resolve any issues promptly. We're always here to help and appreciate your trust in us!

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09/19/2024

ALAN Y.

ALAN Y.

 Verified Buyer
SG

SG

Effective Stuff

I recently started taking Picamilon, and I must say, it has been a game-changer for me. As someone who often deals with anxiety and occasional stress, I was looking for a natural supplement that could help me manage my symptoms without the side effects associated with traditional medications. Picamilon has exceeded my expectations in several ways. First and foremost, I noticed a significant reduction in my anxiety levels shortly after starting the supplement. It provides a calming effect that allows me to tackle daily tasks with a clearer mind. Unlike some other anxiety relief options that can leave you feeling drowsy or lethargic, Picamilon offers a “calm focus”, which is perfect for maintaining productivity throughout the day. Additionally, I\'ve experienced improvements in my cognitive performance. My memory and concentration have noticeably enhanced, making it easier to stay engaged during long work sessions. I feel more alert and motivated, which has positively impacted my overall mood. The combination of GABA and niacin in Picamilon seems to work wonders for boosting brain function while also promoting relaxation. Another aspect I appreciate is how quickly the effects kick in. Within an hour of taking it, I can feel the benefits starting to take hold, which is incredibly helpful during stressful situations or when I need to perform well, such as before meetings or presentations. Moreover, I’ve found that Picamilon helps improve my sleep quality. Since incorporating it into my routine, I\'ve been sleeping more soundly and waking up feeling refreshed. This has contributed to my overall well-being and energy levels throughout the day. Overall, I highly recommend Picamilon to anyone looking for a natural way to enhance their mental clarity, reduce anxiety, and improve their mood. It’s affordable, effective, and has worked wonders for me without any noticeable side effects. If you\'re considering trying it out, I encourage you to give it a shot—you might just find it as beneficial as I have!

09/20/2024

Cosmic Nootropic

Hi Alan! Thank you for such an in-depth and thoughtful review! We’re thrilled to hear that Picamilon has been a game-changer for you. It’s wonderful to know that it’s helping you manage anxiety while enhancing your cognitive performance and overall mood. We appreciate you sharing your experience with how quickly the effects kick in and the benefits for your sleep quality. It sounds like Picamilon has truly become an integral part of your routine! Your recommendation means a lot to us, and we’re here to support you as you continue your journey. If you have any questions or need further assistance, don’t hesitate to reach out.

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09/19/2024

Joe

Joe

 Verified Buyer
US

US

My favorite nootropic so far

Picamilon really helps take the edge off and keep me positive! Was a little afraid my second order wouldn\'t be delivered because cosmicnootropic was not accepting visa at the time but placed order with wise transfer and everything came. Great customer service! Highly recommend and will be buying more.

09/20/2024

Cosmic Nootropic

Hi Joe! Thank you for your fantastic review! We’re so glad to hear that Picamilon is helping you stay positive and take the edge off. It’s also great to know our customer service met your expectations during your ordering process.

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08/21/2024

Julie V.

Julie V.

 Verified Buyer
US

US

Amazing supplement for me

This picamilon is exactly what my brain seems to need for clearing brain fog, as well as efficient problem solving and articulating. Very thankful!

08/22/2024

Cosmic Nootropic

Hi Julie! Thank you so much for your wonderful review! We're thrilled to hear that our Picamilon supplement is helping you with brain fog, problem solving, and articulation. Your satisfaction means a lot to us, and we’re grateful for your feedback.

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08/06/2024

Nick B.

Nick B.

 Verified Buyer
US

US

Great service, great products

Everything I’ve ordered arrived promptly. Quality is always top notch!

08/07/2024

Cosmic Nootropic

Hi Nick! Thank you so much for your kind words! We're thrilled to hear that you're pleased with both our service and products. We always strive to deliver the best, so it's great to know we're hitting the mark :)

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0

08/02/2024

Marko R.

Marko R.

 Verified Buyer
AU

AU

I didnt recieve my item - item got seized at customs

Item never received as it was seized at customs

08/02/2024

Cosmic Nootropic

Hi Marko. We're so sorry to hear that your order was seized at customs. It looks like we have already started working on your problem and have emailed you about it. We have reached out to you again in case you've missed our previous email. We're looking forward to resolving this issue!

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0

07/28/2024

Aaron T.

Aaron T.

 Verified Buyer
US

US

This is good

This stuff is good I really really like it. It works.

07/28/2024

Cosmic Nootropic

Dear Aaron, Thanks for the awesome feedback! We're so glad to hear that you like Picamilon and that it's working for you. If you have any questions or need anything else, feel free to reach out!

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0

07/20/2024

Aaron T.

Aaron T.

 Verified Buyer
US

US

It be the good good use of great

So goodly good. Like bigly good. It’s the gooder of goodest and I love good.

07/22/2024

Cosmic Nootropic

Dear Aaron, Sounds like Picamilon is hitting all the “good” notes :) We're happy to hear that you like it! Thanks for the fun and fantastic review.

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0

07/18/2024

Beomtaek L.

Beomtaek L.

 Verified Buyer
US

US

Great experiece with Cosmic Nootropic

I am a long term user and I am always happy with the product and Cosmis Nootropic.

07/18/2024

Cosmic Nootropic

Hi Beomtaek! Thank you very much for your loyal support and fantastic feedback! We're delighted to hear that you've had a consistently great experience with CosmicNootropic.

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06/28/2024

Sherry F.

Sherry F.

 Verified Buyer
US

US

Picamilon is great

I love picamilon. So many anti-anxiety treatments I have tried create so much fatigue that I can't focus. Not picamilon! It relaxes me during the day without having side effects. I use them at night when I am stressed and can't calm down. Love them!!!!

06/28/2024

Cosmic Nootropic

Hi Sherry! Thank you for your positive feedback on Picamilon! We're thrilled to hear it's helping you manage anxiety effectively without causing fatigue. Your satisfaction is important to us.

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06/20/2024

MICHAEL S.

MICHAEL S.

 Verified Buyer
US

US

Will order more soon

Picamilon works well for me. I will get more shortly

06/20/2024

Cosmic Nootropic

Hi Michael! Thank you so much for your positive feedback! We're thrilled to hear that Picamilon is working effectively for you. Whenever you're ready to reorder, we'll be here to assist you. If you have any questions or need further assistance in the future, please don't hesitate to reach out. Your satisfaction is our priority.

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06/02/2024

Zachary B.

Zachary B.

 Verified Buyer
US

US

Great for leveling me out.

I’ve been taking 1.5 of these daily and occasionally a little more for about 3 months. I’ve noticed my anxiety has gone way down and emotions seem much more leveled out than in a long time. I’ve always been very socially anxious and this has helped tremendously. At first in the bedroom it seemed to have a very negative effect. Very non-intense ****** but after a couple weeks it’s been the opposite. *** has been so much more intense and best in my life… even at 42 male.

06/02/2024

Cosmic Nootropic

Dear Zachary, Thank you for sharing your experience with our product! We're glad to hear it has helped reduce your anxiety and improve your social interactions. It's great to know that you've also seen positive changes in your intimate life.

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1

05/02/2024

Catherine W.

Catherine W.

 Verified Buyer
US

US

PICAMILON: Helped then hurt

I took Picamilon to avert depression and anxiety I experienced prior to having post menopausal hot flashing. And during the first 6 weeks it worked just fine. Then I started to have the sensation that I was going to faint, and had to sit down quickly. This happened several times until I quit taking Picamilon. It took about 4 days to have these effects clear my system. I am afraid to take more of this product because of these near fainting spells.

05/02/2024

Cosmic Nootropic

Hi Catherine! We are sorry to hear about this. While some individuals may find certain nootropics helpful in managing specific symptoms, it’s essential to consult with a healthcare professional for a proper diagnosis and treatment plan tailored to your specific needs. The effect of most nootropics varies from person to person, depending on the personal conditions, so you should definitely consult a doctor on this matter.

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05/02/2024

Lauren C.

Lauren C.

 Verified Buyer
US

US

Picamilon works

We were recommended the use of this product to calm and adjust GABA for my husband. He has high anxiety due to PFS. This appears to blunt some of that anxiety when taken. It does have some getting used to, but definitely calms some of the chaos. Be aware, it could feel like it blunts emotions which is normal.

05/02/2024

Cosmic Nootropic

Hi Lauren! Thank you for leaving your review and sharing your thoughts on the product.

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04/28/2024

Grace M.

Grace M.

 Verified Buyer
CA

CA

It was not what I was expecting but maybe should have done more research

Not bad but I was going for a specific effect and its not the product, it was more me trying something new

04/28/2024

Cosmic Nootropic

Dear Grace, Thank you for sharing your experience. It's great to hear that you were open to trying something new. If you ever need more information, feel free to reach out. We're here to help!

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04/22/2024

John C.

John C.

 Verified Buyer
US

US

Effective GABA

Enhance good rest and clarity the following day.

04/22/2024

Cosmic Nootropic

Dear John, thank you for sharing your thoughts on this product!

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0

04/07/2024

Bodie S.

Bodie S.

 Verified Buyer
US

US

Solid

As far as i can tell theyre good potent products

04/12/2024

Cosmic Nootropic

Hi Bodie! Thank you for your positive review :)

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0

04/01/2024

Mark S.

Mark S.

 Verified Buyer
US

US

Where's my stuff ?

I ordered pills/caps of picamilim and received ampules instead. I returned them but have not received anything! I didn't ask for a refund. Just a replacement. Received zero! Scammed again!

04/02/2024

Cosmic Nootropic

Hi Mark! We are so sorry to hear about this puzzling situation. We have emailed you to see how we can resolve this issue.

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