PRAMISTAR ® (Pramiracetam)

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Pramiracetam was discovered by scientists at Parke-Davis, the USA, in the late 1970s. Being chemically very similar to Choline, Pramiracetam causes the formation of nitric oxide – a powerful vasodilator, which is crucial for short-term memory. It also has an effect on neuropeptide mediation, as a result improving memory and learning processes. One interesting thing about pramiracetam is that it has a higher potency than piracetam: the most common dose is only 600 mg – 4 times smaller than that of Piracetam. Another interesting fact is that it has a very late onset of first effects: in most cases, they should not be expected until 5-6 weeks into the course. Some reviews state that Pramiracetam can also be used as an antidepressant and an anxiety treatment.

 

Buy Pramistar for use in older patients and adults for the following indications:

  • Symptomatic treatment of various memory disorders;
  • Treatment-resistant depressions;
  • Psychoorganic syndrome with asthenia;
  • Emotional lability;
  • Other conditions, characterized by lowered motivation.

 

If used as a mild cognitive enhancer by otherwise healthy people Pramiracetam should be normally taken for a course of 6 to 8 weeks, with main effects starting to manifest after 5-6 weeks of supplementation. Pramiracetam daily dosage is 600–1200 mg. Some individuals report sudden but strong effects such as photographic memory after they take place.

Produced by Berlin-Chemie, Germany / Menarini, Italy.

 

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This product has not been approved by the US FDA. All statements on this page are for informational purposes only and have not been evaluated by the US FDA.
This product is not intended to diagnose, treat, cure, or prevent any disease. See more

Dosage and administration

If you would like to see the official doses, please refer to the drug facts sheet located in each package. The doses are 600 mg once or twice per day.

One pack of Pramistar contains 20 pills, each containing 600 mg of Pramiracetam, which is sufficient for an average of 10 days of supplementation.

Side effects

Side effects occur rarely, with the most common being dry mouth, nausea, pain in the upper stomach, dizziness, and psychomotor agitation.

Overdose

There were no reported cases of overdose.

Note: If used as a mild cognitive enhancer by otherwise healthy people, Pramiracetam should be taken over a course of 6 to 8 weeks, with main effects starting to manifest after 5-6 weeks of supplementation.

Manufacturer

Berlin-Chemie, Germany / Menarini, Italy.

  1. Butler et al (1984) Amnesia-reversal activity of a series of N-[(disubstituted-amino)alkyl] -2-oxo-1-pyrrolidineacetamides, including pramiracetam https://www.ncbi.nlm.nih.gov/pubmed/6716406
  2. Chang et al (1985) Pharmacokinetics of oral pramiracetam in normal volunteers https://www.ncbi.nlm.nih.gov/pubmed/4008675
  3. C Murray, H Fibiger (1986) The effect of pramiracetam (CI-879) on the acquisition of a radial arm maze task https://www.ncbi.nlm.nih.gov/pubmed/3088666
  4. Claus et al (1991) Nootropic drugs in Alzheimer’s disease: symptomatic treatment with pramiracetam https://www.ncbi.nlm.nih.gov/pubmed/2011259
  5. McLean et al (1991) Placebo-controlled study of pramiracetam in young males with memory and cognitive problems resulting from head injury and anoxia https://www.ncbi.nlm.nih.gov/pubmed/1786500
  6. Auteri et al (1992) Pharmacokinetics of pramiracetam in healthy volunteers after oral administration https://www.ncbi.nlm.nih.gov/pubmed/1473879
  7. F Talih, J Ajaltouni (2015) Probable Nootropicinduced Psychiatric Adverse Effects: A Series of Four Cases https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756795/

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