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PRAMIRACETAM (Pramistar ®)
Buy Pramiracetam Online!
Pramiracetam is a piracetam derivative more potent than the original drug. It can improve memory and cognitive functions.
One pack of Pramistar (Pramiracetam) contains 20 pills, it is sufficient for 10-20 days of supplementation. Save with the volume discount!
Fast US delivery available!
|Synonyms||Neupramir / Remen|
|Form:||20 pills of 600mg|
|Form description:||White, elliptical, biconvex, film-coated tablets with break lines on both sides.|
|Active ingredient:||Pramiracetam sulfate – 818.4 mg (equivalent to 600 mg of pramiracetam)|
|Excipients:||Microcrystalline cellulose, colloidal silicon dioxide, crospovidone, calcium stearate, hydroxypropyl methylcellulose, titanium dioxide (E 171), hypromellose, polyethylene glycol 3350, polyethylene glycol 400.|
|Shelf life:||3 years. Do not use it beyond the expiration date printed on the package.|
|Storage conditions:||Store in a dry dark place at temperatures no higher than 30°C (86°F). Keep out of reach of children.|
|Terms of release:||Over-the-counter|
|Manufacturer:||Berlin-Chemie, Germany / Menarini, Italy|
What is Pramiracetam (Pramistar)?
Pramiracetam is a nootropic of the racetam family. Pramiracetam was initially synthesized from piracetam in attempt to find its modifications with greater anti-amnesiac potential. Pramiracetam was discovered by scientists at Parke-Davis, the USA, in the late 1970s.
What is the Mechanism of Action of Pramiracetam?
The mechanism of action of pramiracetam, like piracetam, is not fully understood, however, it is stated that pramiracetam increases neuronal activity and has a high degree of affinity for choline, acting in the cholinergic structures of the brain. Being chemically very similar to Choline, Pramiracetam causes the formation of nitric oxide – a powerful vasodilator, which is crucial for short-term memory. It also has an effect on neuropeptide mediation, as a result improving memory and learning processes.
What are the Benefits and Effects of Pramiracetam?
Pramiracetam has a higher potency than piracetam: the most common dose is only 600 mg – 4 times smaller than that of Piracetam.
Another interesting fact is that it has a very late onset of first effects: in most cases, they should not be expected until 5-6 weeks of treatment.
According to the official instructions, it improves attention, long-term memory formation, and the ability to learn. Some reviews state that Pramiracetam can also be used as an antidepressant and anti-anxiety treatment.
If used as a mild cognitive enhancer by otherwise healthy people Pramiracetam should be normally taken for a course of 6 to 8 weeks, with main effects starting to manifest after 5-6 weeks of supplementation. Some individuals report sudden but considerable effects such as photographic memory.
What is Pramistar (Pramiracetam) User For?
In medical practice, Pramistar is used for the following indications:
- Symptomatic treatment of various memory disorders;
- Treatment-resistant depressions;
- Psychoorganic syndrome with asthenia;
- Emotional lability;
- Other conditions associated with lowered motivation.
Where Can I Order Pramiracetam Online?
You can buy Pramiracetam online at different vendors. CosmicNootropic offers Pramiracetam (Pramistar) in packs of 20x600mg pills. We offer fast US delivery and worldwide shipping with volume discounts! Always be sure to do your research before purchasing any nootropic supplement to ensure you are getting a quality product.
You can order Pramiracetam and get it delivered to the USA, Europe, the UK, Asia, and many other regions and countries via CosmicNootropic.
Check out other products from the Nootropics & Brain Health category!
This product has not been approved by the US FDA. All statements on this page are for informational purposes only and have not been evaluated by the US FDA.
This product is not intended to diagnose, treat, cure, or prevent any disease. See more
What is Pramiracetam Dosage, How to Use It?
If you would like to see the official doses, please refer to the drug facts sheet located in each package. The recommended doses are 600 mg once or twice per day.
What are the Side Effects of Pramiracetam?
Side effects occur rarely, with the most common of them being dry mouth, nausea, pain in the upper stomach, dizziness, and psychomotor agitation.
- Hypersensitivity to the active substance or other components of the drug;
- Cerebral hemorrhage
- Severe renal failure;
- Liver failure.
There were no reported cases of overdose.
Note: If used as a mild cognitive enhancer by otherwise healthy people, Pramiracetam should be taken over a course of 6 to 8 weeks, with main effects starting to manifest after 5-6 weeks of supplementation.
You can find many research papers on this product. We highlighted a few below:
- Butler et al (1984) Amnesia-reversal activity of a series of N-[(disubstituted-amino)alkyl] -2-oxo-1-pyrrolidineacetamides, including pramiracetam https://www.ncbi.nlm.nih.gov/pubmed/6716406
- Chang et al (1985) Pharmacokinetics of oral pramiracetam in normal volunteers https://www.ncbi.nlm.nih.gov/pubmed/4008675
- C Murray, H Fibiger (1986) The effect of pramiracetam (CI-879) on the acquisition of a radial arm maze task https://www.ncbi.nlm.nih.gov/pubmed/3088666
- Claus et al (1991) Nootropic drugs in Alzheimer’s disease: symptomatic treatment with pramiracetam https://www.ncbi.nlm.nih.gov/pubmed/2011259
- McLean et al (1991) Placebo-controlled study of pramiracetam in young males with memory and cognitive problems resulting from head injury and anoxia https://www.ncbi.nlm.nih.gov/pubmed/1786500
- Auteri et al (1992) Pharmacokinetics of pramiracetam in healthy volunteers after oral administration https://www.ncbi.nlm.nih.gov/pubmed/1473879
- Dziak et al (2003) [Experience in the application of pramistar, a new nootropic preparation, in the treatment of memory disorders in patients with cerebrovascular pathology] https://pubmed.ncbi.nlm.nih.gov/14965012/
- A Malykh, M Sadaie (2010) Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders https://pubmed.ncbi.nlm.nih.gov/20166767/
- F Talih, J Ajaltouni (2015) Probable Nootropicinduced Psychiatric Adverse Effects: A Series of Four Cases https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756795/
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Semax® is a Russian peptide with nootropic properties. You can buy Semax to improve mental and physical performance. The drug was shown to increase BDNF which is responsible for the growth and differentiation of new neurons and synapses. Two forms of Semax are available! It can be used for improving attention and memory (Semax 0.1%) and for treating strokes (Semax 1%). Fast US domestic shipping.
It has been more than 40 years since Cornelia E. Giurgea - a Romanian chemist - synthesized a compound that was "capable of selectively influencing integrative mechanisms of the brain”. This chemical compound was Piracetam®, which later gave birth to a whole range of pharmaceuticals which we now call nootropics. Fast US domestic shipping is available.
Nanotropil® (previously known as Phenotropil) was part of the cosmonaut's kit in the USSR. It is a phenyl derivative of Piracetam which is reported to be more neuroprotective compared to the original compound. It was shown to possess psychostimulatory and various adaptogenic and neuromodulator properties. Fast US domestic shipping is available.