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SELANK ®
33 Reviews
Description
Dosage
Research
Reviews
Buy Selank 0.15% Nasal Drops at the Best Price!
Selank is a peptide anxiolytic from Russia. It is available to buy online at a competitive price.
Original factory-produced high-quality!
Selank Description
| International Non-Proprietary Name (INN): | Threonyl-lysyl-prolyl-arginyl-prolyl-glycyl-proline diacetate |
| Form: | Nasal drops 0.15% (3 ml) |
| Form description: | The colorless transparent liquid in a 3 ml dropper bottle |
| Active ingredient: | Selank in terms of 100% substance (threonyl-lysyl-prolyl-arginyl-prolyl-glycyl-proline diacetate) – 1.5 mg; |
| Excipients: | Methyl parahydroxybenzoate (nipagin) – 1 mg, purified water – up to 1 ml |
| СAS Number: | 129954-34-3 |
| ATC code: | N06BX |
| Pharmacological action: | Antianxiety, antiasthenic, nootropic |
| Bioavailability: | 92.8% |
| Shelf life: | 2 years. Do not use beyond the expiration date printed on the package. |
| Storage conditions: | Store at temperatures not exceeding 10°C (50°F), do not freeze, protect from light. |
| Manufacturer: | CJSC ‘Innovation Research and Production Center “Peptogen’. https://selank.ru/ |
What Is Selank?
Selank 0.15% is an anxiolytic peptide with nootropic properties. The main effects include antianxiety, antidepressant, and antiasthenic. By its structure, Selank is based on endogenous tetrapeptide Tuftsin which plays an important role in the immune system.
Selank usually goes in the form of nasal spray or drops.
The History Behind Selank Peptide
Tuftsin was found to have anxiolytic effects in 1995. And over the next decade, Russian scientists were focusing on developing a peptide drug that was able to have the most pronounced anxiolytic effects.
To slow the breakdown of the peptide and prolong its effects, the inventors of Selank added glyproline to its structure. Numerous clinical trials confirmed the safety of this peptide, which was found to be void of dependence and to be non-toxic even in doses 200–500 times higher than therapeutic ones.
This research, as well as clinical trials, lasted until 2009 when Selank was finally brought to market under the brand name Selank 0.15%. It is produced in a GMP-compliant factory by Peptogen Inc. Read more about the producer in this blog post.
How Does Selank Work in the Brain?
The mechanism of the positive therapeutic action of Selank is based on its ability to restore normal levels of serotonin, noradrenaline, and enkephalins in the brain. Further, Selank increases the synthesis of dopamine in the cerebral cortex, which is the basis of stimulating, restoring, and increasing brain activity.
If you want to read more about Selank check out the comprehensive Selank Review in our blog.
Selank and Semax: is there a Difference?
Semax and Selank are two different products. Even though they are both peptides administered nasally, they produce different effects. While Semax is a nootropic and has pronounced stimulating effects, Selank is an anxiolytic. In short, if you are looking for improved focus, mild stimulation, and faster learning – Semax is your choice. Selank will be useful for those looking to release stress, relax, and improve their mood.
What Are the Benefits of Selank Peptide?
The spectrum of the pharmacological action of the drug is wide and unique. It is a popular over-the-counter anti-anxiety medicine with antidepressant and anti-asthenic actions. It also has the capacity to enhance memory and cognitive functions.
Primary Uses of Selank 0.15% nasal drops include:
- Anxiety and adjustment disorders;
- Neurasthenia, emotional lability;
- Stress-related disorders, including GAD, PTSD etc.
Where To Buy Selank Online?
Selank is not FDA-approved, so you will not find it in the US over-the-counter. But you can buy Selank online. There are different forms of Selank: powder, spray, and drops. Make sure to obtain original Selank nasal drops from a trustworthy vendor.
Read more in our in-depth Selank review!
Legal Disclaimer
This product has not been approved by the US FDA. All statements on this page are for informational purposes only and have not been evaluated by the US FDA.
This product is not intended to diagnose, treat, cure, or prevent any disease. See more
How to Use Selank: Dosage?
One bottle of Selank contains 60 drops, each having 75 mcg of the active ingredient. The average dose is 2-3 drops in each nostril. Selank should be taken up to 3 times per day.
The treatment course is 14 days.
Is it Safe to Use Selank?
In short, yes. Selank research and human trials have shown it to be completely safe even in doses exceeding the recommended ones. Selank does not form a dependence, making it safe to use.
Selank has no effect on depressants or stimulants. It can be combined with neuro- and psychotherapy. If you are taking other medications, consult your doctor.
You can read more about Selank peptide nootropic in the ‘Research’ tab above.
Are There Any Side Effects of Selank?
Selank is generally well-tolerated. The side effects listed in the instructions are very rare and include irritation of the nasal mucosa and mild allergic reactions. No cases of overdose were recorded.
Selank and Hair Loss
People frequently ask this question on different platforms including Reddit. But there have been no confirmed cases of Selank causing the loss of hair. Generally, hair loss is largely connected to increased BDNF. Selank is a supplement that can help regulate BDNF.
What is Selank Shelf-Life?
The shelf life of a new product is 2 years if stored properly: in a dark place at a temperature of less than 10°C (50°F).
An opened bottle of Selank can be kept at room temperatures below 30°C (86°F) for a period of up to 30 days.
Selank Reviews
You can check out the ‘Reviews’ tab above. Besides there are also Selank Reddit anecdotal experiences.
OFFICIAL INSTRUCTION
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- Zozulya et al (2001) The inhibitory effect of Selank on enkephalin-degrading enzymes as a possible mechanism of its anxiolytic activity https://www.ncbi.nlm.nih.gov/pubmed/11550013
- Kost et al (2001) Semax and selank inhibit the enkephalin-degrading enzymes from human serum https://www.ncbi.nlm.nih.gov/pubmed/11443939
- Sokolov et al (2002) Effects of Selank on behavioral reactions and activities of plasma enkephalin-degrading enzymes in mice with different phenotypes of emotional and stress reactions https://www.ncbi.nlm.nih.gov/pubmed/12432865
- Kozlovskaya et al (2003) Selank and short peptides of the tuftsin family in the regulation of adaptive behavior in stress https://www.ncbi.nlm.nih.gov/pubmed/14969422
- I. Kozlovkii, N. Danchev (2003) The optimizing action of the synthetic peptide Selank on a conditioned active avoidance reflex in rats https://www.ncbi.nlm.nih.gov/pubmed/14552529
- T. Ganshina, I. Kozlovskii (2005) Effects of the new peptide anxiolytic drug selank on the cardiovascular system functioning and respiration in cats https://www.ncbi.nlm.nih.gov/pubmed/16193654
- Semenova et al (2007) Effect of selank on cognitive processes after damage inflicted to the cerebral catecholamine system during early ontogeny https://www.ncbi.nlm.nih.gov/pubmed/18683497
- Sarkisova et al (2008) Effects of heptapeptide selank on genetically-based and situation-provoked symptoms of depression in behavior in WAG/Rij and Wistar rats, and in BALB/c mice https://www.ncbi.nlm.nih.gov/pubmed/18661785
- Zozulia et al (2008) Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia https://www.ncbi.nlm.nih.gov/pubmed/18454096
- Uchakina et al (2008) Immunomodulatory effects of selank in patients with anxiety-asthenic disorders https://www.ncbi.nlm.nih.gov/pubmed/18577961
- Medvedev et al (2014) A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders https://www.ncbi.nlm.nih.gov/pubmed/25176261
- Kolomin et al (2014) The temporary dynamics of inflammation-related genes expression under tuftsin analog Selank action https://www.ncbi.nlm.nih.gov/m/pubmed/24291245/
- Medvedev et al (2015) Optimization of the treatment of anxiety disorders with selank https://www.ncbi.nlm.nih.gov/pubmed/26356395
- Volkova et al (2016) Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission https://www.ncbi.nlm.nih.gov/pubmed/26924987
- Kaisan et al (2017) Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in Rats https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322660/
- Filatova et al (2017) GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328971/
- Fomenko et al (2017) Effect of Selank on Functional State of Rat Hepatocytes under Conditions of Restraint Stress https://www.ncbi.nlm.nih.gov/pubmed/28853100
- Slominsky et al (2017) Peptides semax and selank affect the behavior of rats with 6-OHDA induced PD-like parkinsonism https://www.ncbi.nlm.nih.gov/pubmed/28702721
- Vyunova et al (2018) Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity https://pubmed.ncbi.nlm.nih.gov/30255741/
- C Doyno, C White (2021) Sedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank https://pubmed.ncbi.nlm.nih.gov/34396551/
- Yasenyavskaya et al (2021) The Influence of Selank on the Level of Cytokines Under the Conditions of “Social” Stress https://pubmed.ncbi.nlm.nih.gov/32621722/
4.2
Based on 33 Reviews
(23)
(2)
(4)
(0)
(4)
11/22/2023
Eric W.
Verified Buyer
US
Selank
I didn't care for the nasal drops. I believe I lost 50% of the product just from the administration process. The nasal drops are high-maintenance and do not travel well. In my job as a nurse I don't get many opportunities to lay on my side and have someone else carefully drop the medication in my nose. The actual nasal spray is the only way I'll take this product moving forward. Selank is effective, but I couldn't really tell because I wasn't able to control the dosage.
11/24/2023
Hi Eric! Thank you for taking the time to leave the review. We understand that the administration process of the product may not be efficient for everybody. We hope that you will find our other products to work better for you.
08/30/2023
Zane M.
Verified Buyer
US
Works Good
All around positive experience with the peptide.
08/30/2023
Dear Zane, thank you for your feedback!
08/07/2023
Chris P.
Verified Buyer
NZ
The good stuff
Most excellent, particularly combined with semax
08/09/2023
Dear Chris, thank you for your feedback, we really appreciate it!
08/02/2023
Phillip P.
Verified Buyer
US
It worked
This worked well. It got the wife out a 2 yr depression, unlike the prescribed anti depressants. It may work different for others. The dropper was a bit funky and was hard to determine proper dosage. It's been 5 weeks since last cycle of 2 weeks and going strong. Would recommend to other to try, can't hurt. Safer than anti depressants.
08/02/2023
Hi Phillip! Thank you so much for your review! We're very happy that the product helped your wife!
05/14/2023
Archie
Verified Buyer
US
Selank is great
I'm really enjoying the benefits of Selank. It really keeps my mood balanced and reduces my social anxiety a lot.
05/21/2023
Thank you for the review, Archie! We're happy to hear that Selank is helping you
03/14/2023
Pascal A.
Verified Buyer
FR
Did nothing
Litterrally did nothing on me at all. Very disappointed 😥
03/15/2023
Hi Pascal, We are sorry to hear that. 😔 Our support team will reach out shortly!
01/27/2023
Tamara F.
Verified Buyer
US
Selank
Awesome product and the website has a great team of professionals.
01/27/2023
Hi Tamara! Thank you for your feedback, really appreciate it! 😊
01/23/2023
VASSILIS M.
Verified Buyer
GR
Excellent overall experience
Im extremely happy with Cosmic Nootropics, with a huge variety of products, excellent customer service and the delivery is as fast as can be. Many thanks!
01/25/2023
Hi Vassilis! Thank you very much for sharing your experience! We're happy that you're satisfied with our service and products. 💙
10/24/2022
David N.
Verified Buyer
FR
I never received this item
Again I never received the product unfortunately
10/26/2022
Hi David, I'm sorry that your item did not arrive. We have contacted you via email to solve this problem. Please check your inbox!
09/07/2022
David
US
No Effect Whatsoever
I purchased Selank for the first time recently. This is a liquid preparation, designed to enter the bloodstream after absorption by the nasal mucosa. That mode of delivery should be more rapid than **** ingestion. With that in mind, my intended use was treatment of occasional episodes of high anxiety (below panic threshold). Unfortunately, I noticed absolutely zero effect from this product, even with 2x dose.
09/07/2022
Dear David, we're sorry for the unpleasant experience. For most nootropics, the effect can be varied for different people. It strongly depends on the personal conditions, so we always recommend consulting a specialist before taking any medication. If needed, please reach out to [email protected], and we can answer your questions in more detail.
08/07/2022
Dolores M.
Verified Buyer
US
Excellent
Everything went great with ordering and the Selank is worth it! The only possible negative has nothing to do with the service or product. I had to sign for the package at the post office and because of the extreme hate towards Russia, the fact that my package came from Russia made the postal workers change their attitude towards me. And it was the fact that it was from Russia because they kept passing the package to each other and staring at the address before bringing it to me, then they refused to make eye contact or even speak to me as I signed for it. Even though I love selank I'm not sure it's safe to order without being put on some fbi watch list because of paranoid postal workers.
08/14/2022
Dear Dolores, we are sorry for this unpleasant experience you've got. We can only suggest you place your further orders from our US warehouse, so you won't have to deal with all that things.
07/02/2022
Devin P.
Verified Buyer
US
Long after I had lost all hope, I finally received it! Seems to be pretty effective too!
So, due to the situation between Ukraine and Russia and all the sanctions, my shipment was stuck in customs for over a month! They even opened one of the boxes of Selank and took one of the Phenylpiracetam pills (for testing I assume - how silly lol). The tracking information was not updating at all during that period, so I had lost all hope that I would ever receive my shipment. Then, one day, I got a notification saying that my shipment was arriving the next day - it had finally been released from customs! It was a very pleasant surprise, that's for sure - I spent quite a lot of money (Selank x8 and Phenylpiracetam) and I was not too happy with our government, to say the least lol. Anyway, the Selank seems to be pretty effective for my anxiety (even after the long trip - but maybe I take more than the suggested dosage - not sure lol). It's not a miracle cure for my social anxiety or anything like that, but it's a nice addition to my anti-anxiety arsenal lol. It's a bit weird trying to administer a dosage though - I was expecting a nasal spray (guess I didn't read the description lol), so it was a bit strange getting used to using a dropper to get the stuff in my nose lol. I also have to try to prevent the liquid from going through my nasal passages and down my throat, because it will only absorb through the mucous membranes in the nasal cavity. So, I try to squeeze the middle of my nose to prevent the liquid from going down my throat. It's just a routine that takes some getting used to. Lastly, Cosmic Nootropic was really excellent when it came to communications - any questions I asked were promptly answered in a very friendly manner. I fully understand that the extreme shipping delays were totally out of the control of Cosmic Nootropic - it's entirely my government's fault lol. Cosmic Nootropic did everything in their power to ensure successful delivery, and to ensure my satisfaction, and I truly appreciate this company. They're a great website to purchase Russian nootropics from (probably the best), and I completely trust them and I'm very thankful for the fact that I eventually received my shipment! They said that they had a 100% successful delivery rate, and I believe it - it just takes forever to arrive from Russia right now due to the current situation. Hopefully Selank will be available from their U.S. warehouse sometime soon, if it isn't already. That would be so much more convenient, and I would definitely be willing to pay the extra price!
06/18/2022
Pavel H.
Verified Buyer
CZ
didnt do much
after all the hype everywhere the only thing I felt was disappointment. I guess it just isn't for me, I'll just stick to kratom.
07/23/2022
Hi Pavel, Sorry for the unpleasant experience. Indeed, the effect varies from person to person depending on the personal conditions. That's why we always recommend consulting a specialist before taking any meds. If needed, please reach out to [email protected], and we can answer your questions in more detail.
12/05/2021
Jack R.
Verified Buyer
NZ
Top notch nslt
Excellent clarity
08/24/2021
Jamie H.
Verified Buyer
AU
Selank
Excellent for short term focus, thought and sentence structure.
05/15/2021
Martin R.
Verified Buyer
US
noticed zero effect :(
spent $80-90 and it didn’t do anything for me at all
05/26/2021
Hi Martin, Sorry for the unpleasant experience. For most nootorpics effect vary from person to person. Personal tolerance is also a thing. Have you followed official instructions? If needed, please reach out to [email protected] and we can answer your questions in more detail.
04/15/2021
Prachi S.
Verified Buyer
NL
fantastic Experience
Overall service and products are really good.
04/11/2021
Amir A.
Verified Buyer
IL
Very good products and customer service
Very great experience. would buy again!
04/06/2021
zena P.
Verified Buyer
US
just awesome
super professional and excellent experience all the way through
02/12/2021
Anthony M.
Verified Buyer
US
Inconsistent and required more than recommended dose
Inconsistent and required more than recommended dose to notice effect. The effects also were not consistent across similar doses? This stuff definitely is worth your interest, but it would be 4-5 stars only if the recommended dose produced consistent results...its cost is affordable to give it a try, just beware of expectations. No side effects at any dose which is also a plus!
03/09/2022
Hi Anthony! Yes, for most nootropics, the effect can vary from person to person pretty much, depending on personal condition. Please email us at [email protected] so that we could discuss this in more detail!
Josefin F. Verified Buyer
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