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SELANK ®
55 Reviews
Buy Selank Online 0.15% Nasal Drops
Selank is a peptide anxiolytic with nootropic properties. The mechanism of the positive therapeutic action of Selank is based on its ability to restore normal levels of serotonin, noradrenaline, and enkephalins in the brain.
International Non-Proprietary Name (INN): | Threonyl-lysyl-prolyl-arginyl-prolyl-glycyl-proline diacetate |
Form: | Nasal drops 0.15% (3 ml) |
Form description: | The colorless transparent liquid in a 3 ml dropper bottle |
Active ingredient: | Selank in terms of 100% substance (threonyl-lysyl-prolyl-arginyl-prolyl-glycyl-proline diacetate) – 1.5 mg; |
Excipients: | Methyl parahydroxybenzoate (nipagin) – 1 mg, purified water – up to 1 ml |
СAS Number: | 129954-34-3 |
ATC code: | N06BX |
Pharmacological action: | Antianxiety, antiasthenic, nootropic |
Bioavailability: | 92.8% |
Shelf life: | 2 years. Do not use beyond the expiration date printed on the package. |
Storage conditions: | Store at temperatures not exceeding 10°C (50°F), do not freeze, protect from light. |
Manufacturer: | CJSC ‘Innovation Research and Production Center “Peptogen’. https://selank.ru/ |
What Is Selank?
Selank 0.15% is an anxiolytic peptide with nootropic properties. The main effects include antianxiety, and antiasthenic. By its structure, Selank is based on endogenous tetrapeptide Tuftsin which plays an important role in the immune system.
Selank usually goes in the form of nasal spray or drops.
What is Selank Used For?
Primary Uses of Selank 0.15% nasal drops listed by the manufacturer include:
- Anxiety and adjustment disorders; [1]
- Neurasthenia, emotional lability; [2]
- Stress-related disorders, including GAD, PTSD, etc. [3]
What Are Selank Peptide Benefits and Effects?
The spectrum of the pharmacological action of the research material is wide and unique. It is a popular anti-anxiety compound that combines mechanisms which are characteristics of antidepressants and psychostimulants. It also has the capacity to enhance memory and cognitive functions.
Is Selank Safe to Take?
In short, yes. Selank research have shown it to be safe. Selank does not form dependence. As nasal drops, Selank absorbs quickly and is said to integrate naturally into metabolism without harming organs or causing addiction.
Selank has no effect on depressants or stimulants. Thus it can be combined with neuro- and psychotherapy, upon your doctor’s prescription.
FAQ:
Where To Buy Selank Online?
Selank is not FDA-approved, so you will not find it in the US over-the-counter. But you can buy Selank online. There are different forms of Selank: powder, spray, and drops. Make sure to obtain original Selank nasal drops from a trustworthy vendor.
How Was Selank Invented?
By its structure, Selank is based on endogenous tetrapeptide Tuftsin which plays an important role in the immune system. Tuftsin was found to have anxiolytic effects in 1995. And over the next decade, Russian scientists were focusing on developing a peptide drug that was able to have the most pronounced anxiolytic effects. To slow the breakdown of the peptide and prolong its effects, the inventors of Selank added glyproline to its structure. Numerous clinical trials confirmed the safety of this peptide, which was found to be void of dependence and to be non-toxic even in doses 200–500 times higher than the therapeutic ones. This research, as well as clinical trials lasted until 2009 when Selank was finally brought to market under the brand name Selank 0.15%. It is produced in a GMP-compliant factory by Peptogen Inc.
Selank and Semax: Is There a Difference?
Semax and Selank are two different products. Even though they are both peptides administered nasally, they produce different effects. While Semax is a nootropic and has pronounced stimulating effects, Selank is an anxiolytic. In short, if you are looking for improved focus, mild stimulation, and faster learning – Semax is your choice. Selank will be useful for those looking to release stress, relax, and improve their mood.
How Does Selank Work in the Brain?
The mechanism of the positive therapeutic action of Selank is based on its ability to restore normal levels of serotonin, noradrenaline, and enkephalins in the brain. Further, Selank increases the synthesis of dopamine in the cerebral cortex, which is the basis of stimulating, restoring, and increasing brain activity.
Can Selank Cause Hair Loss?
People frequently ask this question on different platforms including Reddit. But there have been no confirmed cases of Selank causing the loss of hair. Generally, hair loss is largely connected to increased BDNF. Selank is a supplement that can help regulate BDNF.
What is Selank Shelf-Life?
The shelf life of the new product is 2 years if stored properly: in a dark place at a temperature of less than 10°C (50°F). An opened bottle of Selank can be kept at room temperatures below 30°C (86°F) for a period of up to 30 days.
What Are Selank Reviews?
You can check out the 'Reviews' tab above. Besides there are also Selank Reddit anecdotal experiences.
How Selank Compares to Traditional Anxiolytics?
Traditional anti-anxiety drugs like benzodiazepines (Xanax, Valium) can be habit-forming and sedating. Selank, on the other hand is milder, it doesn’t cause addiction or drowsiness.
Selank Nasal Spray or Drops - Which Is Better?
The original Selank nasal drops pack more safety bonuses compared to nasal spray form. When taken via nasal route of administration, Selank bypasses the digestive system and goes straight to the brain through the olfactory nerve. This also makes it faster-acting and more bioavailable compared to oral or sublingual methods.
What is Selank Dosage?
One bottle of Selank contains 60 drops, each having 75 mcg of the active ingredient. The average dose is 2-3 drops in each nostril. Selank should be taken up to 3 times per day.
The treatment course is 14 days.
What Are Selank Side Effects?
Selank is generally well-tolerated. The side effects listed in the instructions are very rare and include irritation of the nasal mucosa and mild allergic reactions. No cases of overdose were recorded.
For more information on Selank dosages and side effects, please refer to the translated official drug sheets.
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- Zozulya et al (2001) The inhibitory effect of Selank on enkephalin-degrading enzymes as a possible mechanism of its anxiolytic activity
- Kost et al (2001) Semax and selank inhibit the enkephalin-degrading enzymes from human serum
- Sokolov et al (2002) Effects of Selank on behavioral reactions and activities of plasma enkephalin-degrading enzymes in mice with different phenotypes of emotional and stress reactions
- Kozlovskaya et al (2003) Selank and short peptides of the tuftsin family in the regulation of adaptive behavior in stress
- I. Kozlovkii, N. Danchev (2003) The optimizing action of the synthetic peptide Selank on a conditioned active avoidance reflex in rats
- T. Ganshina, I. Kozlovskii (2005) Effects of the new peptide anxiolytic drug selank on the cardiovascular system functioning and respiration in cats
- Semenova et al (2007) Effect of selank on cognitive processes after damage inflicted to the cerebral catecholamine system during early ontogeny
- Sarkisova et al (2008) Effects of heptapeptide selank on genetically-based and situation-provoked symptoms of depression in behavior in WAG/Rij and Wistar rats, and in BALB/c mice
- Zozulia et al (2008) Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia
- Uchakina et al (2008) Immunomodulatory effects of selank in patients with anxiety-asthenic disorders
- Medvedev et al (2014) A comparison of the anxiolytic effect and tolerability of selank and phenazepam in the treatment of anxiety disorders
- Kolomin et al (2014) The temporary dynamics of inflammation-related genes expression under tuftsin analog Selank action
- Medvedev et al (2015) Optimization of the treatment of anxiety disorders with selank
- Volkova et al (2016) Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission
- Kaisan et al (2017) Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in Rats
- Filatova et al (2017) GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells
- Fomenko et al (2017) Effect of Selank on Functional State of Rat Hepatocytes under Conditions of Restraint Stress
- Slominsky et al (2017) Peptides semax and selank affect the behavior of rats with 6-OHDA induced PD-like parkinsonism
- Vyunova et al (2018) Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity
- C Doyno, C White (2021) Sedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank
- Yasenyavskaya et al (2021) The Influence of Selank on the Level of Cytokines Under the Conditions of “Social” Stress
4.1
Based on 55 Reviews
(37)
(3)
(6)
(0)
(9)
03/23/2025
Amanda C.
Verified BuyerUS
Amazing!
I feel so focused
01/01/1970
CosmicNootropic
Dear Amanda, thank you for your feedback! 🙌
03/06/2025
Taylor
Verified BuyerUS
waste
received two empty bottles of Semax and two nearly-empty bottles of Selank. I ordered Selank once before and the bottle came half full (i used for a week and put in the photo on the end with the dropper for reference). i want to return these for a refund but customer service is adamant on store credit or reshipment— they also said the two nearly-empty bottles of Selank are “probably fine” to use. I don’t appreciate the idea of using a medical product that is “probably fine” to use per a customer service rep. seriously disappointed in Cosmic Nootropic when i was excited to try an alternative to prescription meds. would rather be anxious in general than anxious over these products (or should i say lack there of). what a waste of time and money.
01/01/1970
CosmicNootropic
Dear Taylor, thank you for sharing your experience. We are very sorry that you had such an unpleasant experience and apologize on behalf of our company. We have already contacted you by email to resolve the issue. Please check it out.
02/28/2025
Justin F.
Verified BuyerUS
Hands down my favorite Neuroprotective peptide Nootropic
Hands down my favorite Neuroprotective nootropic as I suffer from moderate/severe PTSD, anxiety and treatment, resistant depression, the first one I purchased directly from Cosmic and came in the brand name form directly from the manufacturer and I felt immediate relief within second after applying the first few drops in both my left and right nostrils, peaceful, gentle serene, feeling of calmness stillness, as well as focus, now the drawbacks with anything that modulates and is agonistic on GABA receptors, come the short lifved relief Do you too tolerance buildup, which can happen very quickly that is why I try to use it as needed sparingly and even take breaks at times if needed, The price is great you can’t be $20 .00 And the only other drawback is the vials are only half full, which is not a mistake or error. That is exactly how much is supposed to be in them. It’s just a shame they’re not filled all the way.and being the reason so nant graduate on the NA Amidate form of it, and the only other drawback, surely not just the formula from cosmic tropics, but just the nature of the peptide in general is dryness irritation, and sometimes scabbing around the tip of the nostril area that’s why you have some then there who have made it into a Diacetate form to reduce that nasal mucosa, dryness, redness, and irritation but overall, I absolutely love this anxiolytic/anti-depressive and antithetic peptide!! Thank you Cosmic Nootropicd and this of course is a subjective review. Always do your own research and or control with your primary care physician or general practitioner first is recommended. Thank you to the fabulous, always quick, kind, courteous, and friendly staff and support at Cosmic and Cosmic Nootroics For not only going above and beyond will even help try to source and locate a product for you, and that really made me a truly dedicated loyal, grateful and appreciative customer for life and Their ultra reliable and fast shipping and delivering speeds What can I say, Cosmic Nootropics is simply just Excellent in all areas thank you and live healthy and live well Kind Regards, Justin
01/01/1970
CosmicNootropic
Wow, thank you for such an in-depth and thoughtful review! We really appreciate you sharing your experience and insights — it means a lot to us. We’re glad to hear that Selank has been helpful for you and that you’ve had a great experience with our team and service. Noted on the nasal irritation and tolerance buildup — it’s always good to use these products mindfully. And yes, the vial fill level is as intended, but we totally get how it might seem surprising at first!
12/26/2024
Justin F
Verified BuyerUS
Relief!
I wanted to say thank you guys again not only for your amazingly fast delivery times and low prices but for being a a rare gem as far I’m concerned and glimmer of hope for someone who suffers from horrible PTSD and panic disorder this has been truly amazing even if the relief is only temporary or is always there I still am very grateful and do what I can to get the word out about you guys, thank you again and look forward to placing more orders soon!
01/01/1970
CosmicNootropic
Hi Justin! Thank you so much for sharing your experience with us. It truly means the world to know that we've been able to bring you some relief and positivity. We're deeply grateful for your kind words and your trust in us. Your support and willingness to spread the word about us are incredibly appreciated. Please know we're here for you, and we look forward to continuing to provide the service and products you need. Thank you again, and we wish you all the best on your journey to healing and comfort! ❤️
12/06/2024
Nazar
Verified BuyerAU
don\'t bother
they have no control on their delivery company they use. you can\'t chase it. they won\'t contact the shipping company. and the shipping company only receives complains from inside USA. so if you outside USA they won\'t bother solve your problem. all they will do and say we understand your frustration and sorry.
12/02/2024
Morgan H.
Verified BuyerUS
Doesn’t work
Didn’t do anything
01/01/1970
CosmicNootropic
Hi Morgan! Thank you for sharing your feedback! We understand that everyone's experience with products can vary, as each person’s body may respond differently. That’s why we always recommend consulting with a medical professional before starting any new medication or supplement. Your health and safety are our top priority, and a healthcare provider can offer personalized advice based on your specific needs.
11/15/2024
shah
Verified BuyerUS
selank droppers
used selank droppers with a protocol of 2 drops per nostril, once in the morning and again before bed for a total of 3 weeks. felt restorative sleep after long days of studying. highly recommend for those looking for long term benefits after putting in crazy hours for studying!
01/01/1970
CosmicNootropic
Hi Shah! Thank you for sharing your experience with Selank! We're glad to hear it made a positive difference, especially by supporting restorative sleep after intense study sessions. Your detailed feedback and recommendation are much appreciated—wishing you continued success!
11/05/2024
Yeras R.
Verified BuyerUS
Selank
Excellent service, fast delivery and excellent quality of the product, strongly recommended.
01/01/1970
CosmicNootropic
Hi Yeras! Thank you so much for your positive feedback! We're thrilled to hear that you were pleased with our service, delivery speed, and product quality. It means a lot to us that you'd recommend us!
10/29/2024
Jim B.
Verified BuyerCA
Great Product
I felt Selank was a good fit for my condition. However it must continually be pointed out that as good a company that Cosmic Nootropics is with products and services..... Delivery to Canada absolutely sucks!!!! I love Cosmic Nootropics BUT I'm not sure I'll order from them anymore because the shipping is completely unreliable. You just can't keep blaming customs!!! Figure it out please.
01/01/1970
CosmicNootropic
Dear Jim, thank you for your review and for your kind words about our products! We’re glad to hear that Selank has been a good fit for you. We truly value your feedback regarding the shipping issues to Canada. We understand how frustrating unreliable delivery can be, and we will certainly look into this issue. Your support means a lot to us, and we hope to provide you with a better experience in the future. If you have any other concerns or suggestions, please feel free to reach out.
10/17/2024
Aman I.
Verified BuyerGB
Review
Pleasent and surprising
01/01/1970
CosmicNootropic
Hi Aman! Thank you for your thoughtful review! We’re glad to hear you had a pleasant experience and that our product surprised you in a positive way. If you have any specific feedback or suggestions that could help us earn that fifth star, we’d love to hear it!
10/09/2024
Connor G.
Verified BuyerUS
Very beneficial
Very effective for stress relief and mental calmness. Enjoyed stacked with Semax
01/01/1970
CosmicNootropic
Hi Connor! Thank you for your review! We’re so glad to hear that you found our product beneficial for stress relief and mental calmness. It’s great to know you enjoyed stacking it with Semax! If you have any more tips or feedback, feel free to share. We're here to help!
09/29/2024
Cecil K.
Verified BuyerUS
Works for me
It’s been great I adjusted the instructions and take only on the weekends or when feel very anxious n stressed.
01/01/1970
CosmicNootropic
Hi Cecil! Thank you for your feedback! We’re glad to hear that you found a routine that works for you. Adjusting the dosage to fit your needs is a smart approach. We appreciate your trust in us!
09/13/2024
Josh
Verified BuyerUS
Love it!
I have very high anxiety. Sometimes it can make me nearly un functional. It completely removes anxiety from me without making me feel tired or strange. I have never taken anything like this that actually really and truly removes all anxiety and allows me get on with a clear head.
01/01/1970
CosmicNootropic
Thanks so much for the feedback! We're really happy to hear that Selank has made such a difference for your anxiety without any weird side effects.
09/03/2024
Vanessa I.
Verified BuyerNZ
No change or imporvement
I haven't noticed any changes in mood, memory/focus, anxiety/sleep or overall cognition. I took this to help with depression and memory most notably, although i appreciate this product likely would require 3-6m of use, without any benefit noted so far im struggling to want to commit to a longer protocol, as in my experience i usually notice some slight improvement within 4 weeks (at least improved HRV- which unfortunately even in this time of very little life stress has not improved with selank). Great company, i appreciate the diverse product selection, customer service and ability to pay with CC. will try other prodcuts
01/01/1970
CosmicNootropic
Dear Vanessa, we are sorry that the product did not have the expected effect for you. 😓 For most nootropics, the effect can be varied for different people. It strongly depends on the personal conditions, so we always recommend consulting a specialist before taking any medication. But we appreciate your warm words about our company and look forward to having you as a customer in the future!
08/24/2024
Joe M.
Verified BuyerUS
SeLANK
I felt like it was just water
01/01/1970
CosmicNootropic
Hi Joe! Thank you for your feedback. We're sorry to hear that you didn't find the product effective. We strive to ensure the highest quality and efficacy in our products.
07/09/2024
Daniel R.
Verified BuyerUS
Selank
I liked the effects of Selank but I didn’t like using the drops. I had a hard time keeping it in my nose and not drip out or down my throat. Cosmic was great and shipped pretty fast.
01/01/1970
CosmicNootropic
Hi Daniel! Thank you for your feedback! We're glad to hear that you found Selank effective, but we're sorry to hear about the difficulty you experienced with the application process. We're also thrilled that you had a positive experience with Cosmic and our shipping services.
06/02/2024
Cathelin J.
Verified BuyerUS
Selank is great for me. Cosmic Nootropic is just fabulous
I love Selank. It gives me a nice little anxiolytic boost without feeling sedating or drugged. The version sold by cosmic works well consistently. Cosmic is the best. I had a shipment delayed in transit once and they resent and had a new shipment in a few days. Thanks so much for having this product and the excellent service.
01/01/1970
CosmicNootropic
Hi Cathelin! Thank you for your glowing review! We're delighted to hear that Selank has been such a positive addition to your life. We take great pride in providing high-quality products and exceptional service to our customers, and we're glad to hear that your experience reflects that. We once again apologize for any inconvenience caused by the delayed shipment. Your satisfaction is our top priority, and we appreciate your continued support!
05/28/2024
Ethan D.
Verified BuyerUS
Helped with anxiety
Less overall anxiety and generally calmer
01/01/1970
CosmicNootropic
Hi Ethan! Thank you for sharing your experience with us! We're glad to hear that Selank has been helpful for you!
05/02/2024
Cathy S.
Verified BuyerUS
I didn't really notice a difference
It was difficult to figure out how to get just 3 drops but I finally did but can't say you that I noticed anything.
01/01/1970
CosmicNootropic
Hi Cathy! We are sorry to hear that this product did not work for you. Please note that the effect of most nootropics varies from person to person, depending on the personal conditions, so we recommend consulting a doctor before taking any medication.
03/05/2024
Carlos F.
Verified BuyerPT
Did not receive it
Did not receive it
01/01/1970
CosmicNootropic
Dear Carlos, we are very sorry that your order has not been delivered. 😓 Unfortunately, we are not able to do anything with this. According to our experience, Portugal has a very strict import policy on nootropics and supplements in general, that’s why this country is on our high-risk destinations list. It means that we do not guarantee refund or reshipment in case something happens to the parcel during the shipping because it’s completely out of our control. Please check our Reshipment & Refund Policy.
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