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SEMAX ® Nasal Spray Drops | Semax Spray
106 Reviews
Description
Dosage
Research
Reviews
Buy Semax nasal drops at the best price!
Semax is a peptide nootropic that has been proven to support brain health and mental function.
2-Week Course of Semax 0.1% is 2 Bottles of 3 ml
Semax Spray Drops Information
| INN | Methionyl-glutamyl-histidyl-phenylalanil-prolyl-glycyl-proline |
| Form: | Nasal drops 0.1% and 1% |
| Form description: | The colorless transparent liquid in a 3 ml dropper bottle. One bottle of Semax contains 60 drops, each having 50 mcg of the active ingredient. |
| Active ingredient: | Semax as per 100% substance (1l): 0.1% – 1 g; 1% – 10g. |
| Excipients: | Methyl parahydroxybenzoate (nipagin) – 1 g, purified water – up to 1 l. |
| СAS Number: | 80714-61-0 |
| ATC code: | N06ВХ |
| Pharmacological action: | Nootropic, antioxidant, anti-hypoxic, cerebroprotective |
| Bioavailability: | 60-70% |
| Shelf life: | 2 years. Do not use it beyond the expiration date printed on the package. |
| Storage conditions: | Store at temperatures not exceeding 10°C (50°F). Do not freeze. Protect from light. |
| Legal Status: | Unscheduled |
| Manufacturer: | CJSC Peptogen https://semax.ru/ |
What are Semax Spray Drops?
Semax (sometimes mistakenly called “c max”) is a Russian peptide nootropic. The Semax spray comes in the form of nasal drops. And it is used to improve cognitive functions and treat various brain conditions.
By its structure, Semax is a fragment of endogenous neuropeptide ACTH. The drug was shown to increase BDNF which is responsible for the growth and differentiation of new neurons and synapses.
What are the Semax Spray Drops Benefits?
Semax nootropic is manufactured in two dosage forms: Semax 0.1% and Semax 1%. What are they used for? – According to the manufacturer Semax can be used in complex with other medications for the treatment of the following conditions:
Semax 0.1% Uses:
- Increase of attention and memory during repetitive and monotonous tasks;
- Improvement of adaptive capacity of the human body in extreme conditions and in extreme circumstances;
- Alleviation of cognitive impairments caused by cerebrovascular disorders, traumatic brain injuries, and neurosurgery;
- Cognitive disorders in kids above 7 y.o. including ADHD.
Semax 1% Uses:
- Prevention and treatment of circulatory disorders including stroke;
- Acute ischemic stroke and treatment of cognitive impairment caused by stroke;
- Transient ischemic attacks;
- Acute period of traumatic brain injury.
Watch the Semax video review on YouTube
Semax vs. Selank: What’s the Difference?
Semax and Selank are two very different products. Even though they are both peptides administered nasally, they produce different effects. While Semax is a nootropic and has pronounced stimulating effects, Selank is an anxiolytic.
In short, if you are looking for improved focus, mild stimulation, and faster learning – Semax is your choice. Selank will be useful for those looking to release stress, relax, and improve their mood.
Where to Buy Semax?
You can obtain the original Semax nasal drops of the highest quality at Cosmic Nootropic. You can choose fast US delivery or international shipment.
There are other forms of Semax available for purchase. You might have heard about Semax nasal spray, N-Acetyl Semax, N-Acetyl Semax Amidate, or Adamax. But these forms of Semax peptide are unconventional.
If you are looking for a nootropic with the best safety-effectiveness ratio – Semax nasal drops are your choice!
Read more in our in-depth review of Semax
Legal Disclaimer
This product has not been approved by the US FDA. All statements on this page are for informational purposes only and have not been evaluated by the US FDA.
This product is not intended to diagnose, treat, cure, or prevent any disease. See more
How to Use Semax: Dosage?
With the purpose of enhancing cognitive ability, Semax is to be taken 1-2 times a day, 2 drops into each nostril, for a period of 3 to 14 days.
One bottle of Semax contains 60 drops, each having 50 mcg of the active ingredient. Depending on the chosen regimen, one bottle of the drug is sufficient for a course of 3–10 days.
Note
If there is a need to increase the effect of Semax, a second dose can be taken 15 minutes after the first one. Using a stronger version of Semax might not necessarily result in a stronger effect of the therapy.
Does Semax Have Any Side Effects?
Semax is a very safe peptide. The only side effects that have been officially recorded are irritation of the nasal mucosa and very rare allergic reactions.
Semax Storage Conditions: How to Store it Properly?
Keep Semax drops in a dark place at a temperature of less than 10°C (50°F). Do not freeze it.
An open bottle of Semax can be stored for as long as six months without losing its properties if stored properly. The shelf-life of a new product is 2 years.
Can I keep Semax at Room Temperature?
There is a safe preservative in the composition of Semax. That is why you can keep it at room temperatures below 30°C (86°F) for a period of up to 30 days. Exposure to direct sunlight is not recommended. For longer periods of time, Semax should be stored in the refrigerator.
OFFICIAL INSTRUCTION – Semax 0.1%
OFFICIAL INSTRUCTION – Semax 1%
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- Asmarin et al (1997) A nootropic adrenocorticotropin analog 4-10-semax (l5 years experience in its design and study https://www.ncbi.nlm.nih.gov/pubmed/9173745
- Miasoedova et al (1999) Investigation of mechanisms of neuro-protective effect of semax in acute period of ischemic stroke https://www.ncbi.nlm.nih.gov/pubmed/10358912
- Gusev et al (2005) Semax in prevention of disease progress and development of exacerbations in patients with cerebrovascular insufficiency https://www.ncbi.nlm.nih.gov/pubmed/15792140
- Eremin et al (2005) Semax, an ACTH(4-10) analogue with nootropic properties, activates dopaminergic and serotoninergic brain systems in rodents https://www.ncbi.nlm.nih.gov/pubmed/16362768
- Dolotov et al (2006) Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus https://www.ncbi.nlm.nih.gov/pubmed/16996037
- SJ Tsai (2007) Semax, an analogue of adrenocorticotropin (4-10), is a potential agent for the treatment of attention-deficit hyperactivity disorder and Rett syndrome https://www.ncbi.nlm.nih.gov/pubmed/16996699
- Agapova et al (2008) Effect of semax on the temporary dynamics of brain-derived neurotrophic factor and nerve growth factor gene expression in the rat hippocampus and frontal cortex https://www.ncbi.nlm.nih.gov/pubmed/18756821
- Grivennikov et al (2008) Effects of behaviorally active ACTH (4-10) analogue – Semax on rat basal forebrain cholinergic neurons https://www.ncbi.nlm.nih.gov/pubmed/18431004
- Shadrina et al (2010) Comparison of the temporary dynamics of NGF and BDNF gene expression in rat hippocampus, frontal cortex, and retina under Semax action https://www.ncbi.nlm.nih.gov/pubmed/19662538
- Manchenko et al (2010) Nootropic and analgesic effects of Semax following different routes of administration https://www.ncbi.nlm.nih.gov/pubmed/21268834
- Medvedeva et al (2014) The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987924/
- Shypshyna et al (2015) Effect of peptide semax on synaptic activity and short-term plasticity of glutamatergic synapses of co-cultured dorsal root ganglion and dorsal horn neurons https://www.ncbi.nlm.nih.gov/pubmed/26552305
- Medvedeva et al (2017) Semax, an analog of ACTH(4-7), regulates expression of immune response genes during ischemic brain injury in rats https://www.ncbi.nlm.nih.gov/pubmed/28255762
- Gusev et al (2018) The efficacy of semax in the tretament of patients at different stages of ischemic stroke https://www.ncbi.nlm.nih.gov/pubmed/29798983
- Lebedeva et al (2018) Effects of Semax on the Default Mode Network of the Brain https://www.ncbi.nlm.nih.gov/pubmed/30225715
- Samotrueva et al (2019) Experimental Substantiation of Application of Semax as a Modulator of Immune Reaction on the Model of “Social” Stress https://pubmed.ncbi.nlm.nih.gov/31028579/
- Elagina et al (2020) Correction of Lipid Metabolism Disorders in Diabetes Mellitus with Peptide Drugs https://pubmed.ncbi.nlm.nih.gov/32246363/
4.4
Based on 106 Reviews
(83)
(5)
(4)
(4)
(10)
09/22/2023
Neil R.
Verified Buyer
AU
Semax
I liked the product. But it is hard to figure out how much to take. I probably used less than the recommended dosage as a result.
09/22/2023
Hi Neil! According to the official instructions, you should take 2 drops into each nostril, for a period of 3 to 14 days. If you have any additional questions regarding the product, please feel free to contact us at [email protected]. We are happy that you still found yourself satisfied with the product!
09/22/2023
Dolores M.
Verified Buyer
US
Life restoring!
For me this is a life saving noot. Having 2 confirmed strokes and the VA hospital doing little to help and sometimes made it worse, finding Semax has been a Godsend to me. After all the drugs & therapy the VA pumped in me making me worse, it was only after taking Semax that my cognitive functions became restored and I can live my daily life as me, instead of struggling.
09/22/2023
Dear Dolores, we're glad to hear that Semax has had such a positive impact on your life. It's wonderful to know that it has helped you with such a serious problem. Thank you for sharing your experience with us!
09/08/2023
Nicholas M.
Verified Buyer
US
Widened concentration
I quit table tennis even though I had a great rating, to concentrate on my expressive painting art career. But even-though I won a *******-Krasner grant & showed in Manhattan galleries I missed ping pong! After 10 years layoff I needed a tt robot but progress was slow! After using Semax I became much more perceptive! I had tunneled my vision; became lazy! Now I saw the ball all the way to the racket!! And I am progressing F A S T! Scope of vision and watching the ball into contact made a big difference. I am not gues--estimating the ball! Now I am eyballing it to contact & watching my own stroke! WONDERFUL.
09/10/2023
Dear Nicholas, thank you for such extensive review on Semax! we're happy to know it is working well for you!
09/02/2023
amaan S.
Verified Buyer
IN
Undelivered
It wasn't delivered due to your shipping issues
09/17/2023
Dear Amaan, yes indeed, unfortunately, we can't ship from the US these days, but you can order products from our Rus/Kaz warehouse. Please let us know via email if you need any further assistance with placing an order
08/07/2023
Chris P.
Verified Buyer
NZ
The big chill
Most excellent, particularly combined with selank
08/09/2023
Dear Chris, thank you for your feedback, we really appreciate it!
08/07/2023
Shan k.
Verified Buyer
US
1st time
Seemed good.
08/09/2023
Thank you for your feedback!
08/02/2023
Alexander H.
Verified Buyer
US
Great stuff
Everything I’ve gotten from cosmic has been top notch! Semax is no exception!
08/02/2023
Hi Alexander! Thank you so much for the review! :)
07/22/2023
Mark K.
Verified Buyer
US
The product was only a third full when received.
There wasn't much left in the package, and what was in there quickly evaporated before I could use it.
08/04/2023
Hi Mark! Please note that a bottle of Semax is about 10ml in volume but there is only 3ml of solution inside. That's why it may look to be 1/3 full. However, we would appreciate it if you sent us a picture of your product when you received it, so we can resolve this issue with you.
07/21/2023
E-N
Verified Buyer
US
Fast Delivery, High Quality Product.
Great experience with the vendor, quick shipping. Product was in good shape, high quality and offered noticeable and desired effects.
07/21/2023
Hi! Thank you for your kind feedback! We're thrilled to hear that you are satisfied with our products and service. :)
07/17/2023
Luo
Verified Buyer
US
2 out of 3 bottles came empty.
I ordered three 3ml bottles of the 1% Semax. One was filled . The other two were empty. In other words, you shorted me out of 66% of my order. Of course, because I was unlucky enough to pick out the one filled bottle first, I had every reason to trust the other two. TO ALL THOSE USING THIS WEBSITE FOR THE FIRST TIME: You should know that you only have 3 days after receiving your order to make a complaint, should it be damaged or incorrect. Always read the fine print. And, of course, I didn\'t notice until it was too late. Either way, this is still unacceptable, and I will not be buying from Cosmic Nootropic again. Goodbye.
07/19/2023
Hi Luo! I'm sorry to hear that you received empty bottles of Semax.😔 We think this is a problem on the manufacturer's side. Some of our customers have also recently reported receiving an empty bottle. In these cases, we do a reshipment no matter how much time has passed since receiving the package. Unfortunately, you did not contact us, so we could not help you. But now we have emailed you, please check it out!
07/15/2023
Coco T.
Verified Buyer
BR
Fast shipping, product arrived as expected! Might need a cold-pack though.
Super fast shipping to the middle of the United States. I was pleased that everything needed arrived intact (nootropic and the dropper). Although, I noticed that the nootropic should be stored at a temperature NO HIGHER than 50F. It is the middle of summer while writing this. I\'m nervous that the product might have started to degrade, but there is no evidence of that so far. Hopefully, it is still viable! I have an extensive exam coming up, so we will see if it will aid focus and stamina for the next few weeks! Thanks again!
07/19/2023
Hi Coco! Thank you for your feedback! According to the instruction, Semax should be stored at temperatures not exceeding 10 °C (50 °F). But when it is stored at temperatures between 10°C (50°F) to 30°C (86°F) the storage duration is anywhere between 30 days to 3-6 months, depending on the temperature. It is because the product contains methylparaben (0.01%), which works as a preservative and ensures longer shelf-life. It is considered safe and is frequently used in other drugs. Also, the product is sterile and is produced in a GMP-compliant factory, which is likely to increase storage duration. Moreover, most of the time, parcels are not exposed outside, but at warehouses, transports, sorting centers (temperature there is not high). So you don't have to worry, the product is fine :)
07/11/2023
Anthony A.
Verified Buyer
US
It didn’t do anything
I felt nothing and I was very disappointed.
07/13/2023
Dear Anthony, we're sorry the product didn't work for you. For most nootropics, the effect can be varied for different people. It strongly depends on the personal conditions, so we always recommend consulting a specialist before taking any medication.
06/30/2023
Jason
Verified Buyer
US
A Bottle for Ants
Product quality seems fine, just make sure you pay attention to what you\'re getting. 3ml = ~0.11 Oz. of product!
07/16/2023
Hi Jason, thanks for your feedback! Unfortunately, the manufacturer of Semax only produces it in a volume of 3ml. :(
06/23/2023
Yusuf S.
Verified Buyer
US
Semax/Semac
This changed my life big time.
06/23/2023
Hi Yusuf, we're glad to hear that Semax has had such a positive impact on your life!
06/22/2023
Artur A.
Verified Buyer
US
Overview of the products I’ve tried so far!
First of all- thank you cosmic nootropics! Very professional, legit company! So far I tried: Mexidol - works great, good product. Had stronger effects specially when I used it for the first time. Noopept - Great 👍 really works. The only thing which worked for me, non of those racetams worked at all. Phinebut (works great, definitely relaxes, maybe better sleep ) Stressam - didn’t do nothing to me (tried it for a wile in different kind of situations, different doses) Semax - didn’t do nothing at all (tried all kinds of doses - nothing worked) Meldonium - I’m very surprised! Did nothing except making me very sleepy, like really sleepy 😴 Kinda very strange because I expected opposite effects.
06/23/2023
Dear Artur, thank you for finding a moment to leave a review! We're thrilled to hear that you are satisfied with our products and service. :) As for the products you didn't find working for you, the effect can be varied for different people. It strongly depends on the personal conditions, so we always recommend consulting a specialist before taking any medication.
06/16/2023
mac
Verified Buyer
US
rip off
smallest bottle ive ever gotten for the money
06/16/2023
Dear Mac, thank you for sharing your experience. We're sorry your expectations were not met. 😞
04/22/2023
Connor W.
Verified Buyer
GB
Never arrived
Didn’t get to experience it because it never arrived massive waste of money
04/28/2023
Dear Connor, We are very sorry that the package was lost in transit. We have already contacted you by email to suggest a refund or reshipment. Please let us know right away if more than one month has passed since the shipment🙏
04/14/2023
Sterling, C.
Verified Buyer
US
Great company
After so many changes in the nootropic company finding these guys has been amazing! Super good communication and great products plus very fast shipping! I would definitely do business again!
04/26/2023
Thank you so much for your kind words! 😊
04/01/2023
Claude-Marie B.
Verified Buyer
FR
Very useful and powerful compound
Semax is quite an unique beast. It is mainly used to help recovering from strokes but on an healthy brain, it can do wonders. It elevates the level of BDNF (like Noopept and some others Nootropics), have an antidepressant effect (but does not work the same way as SSRI or things like Tianeptine). It can give a boost in confidence and energy and is very useful when you have to work a lot on complex tasks, it helps be focused and clear headed. I think Semax is, like Noopept and Phenylpiracetam, a must have for any person interested in nootropics.
04/02/2023
Thank you so much for such a detailed and useful review! Happy to know our products work for you.
03/19/2023
Ezana
Verified Buyer
ET
Semax
Happy with the product and customer service was very helpful. Delivery was fast and went off without a hitch. Highly recommend both Semax and Cosmic!
03/20/2023
We're happy to hear that! Hope to see you as our customer again :)
Sterling, C. Verified Buyer
Ryan L. Verified Buyer
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Shane S. Verified Buyer
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