ChatGPT has a lot of good things to say about this, and it explains how it works by not directly touching GABA-A but mainly helps produce more neurosteroids like allopregnanolone, one that is known to help anxiety and sleep. By using neurosteroids, it seems to help with GABA-A upregulation according to ChatGPT, so after years of downregulation from benzos and phenibut, this sounded appealing to give a try. After 3 months on/off, I found it has helped restore my sleep, as I can tell if I do not take it. For a while I split one capsule twice a day. Taking one at bedtime could be hit or miss, helping me relax or it could tip me into overstimulation, but with taking this half capsule instead, it always worked without the overstimulation, and now my system is much more stable, and I can tolerate 2 full capsules twice a day (AM and PM about 13 hours apart). Helps in a subtle way that a full regimen of daily dosing seemed to improve. I also take this at different doses during the month, as it helps when my progesterone (which converts to allopregnanolone) dips, and etifoxine helps take off the edginess and smoothes rebound insomnia from that crash. Helps smooth mood and overall nervous system balance for me! I would rate 5 stars but had some hit or miss days and finding the right dosing took some time, but I am happy to find lowering my dose temporarily helped fix any negative aspect of taking this. I want to note that I take buprenorphine daily, and ChatGPT told me that bupe suppresses production of neurosteroids, so it was possible to blunt the full benefits/effects of etifoxine!

Love Cosmic! Just the best customer service ever. I appreciate them so much!

My experience with this non-benzodiazepine anxiolytic medication that I am still somewhere in the middle with with, some articles claim it’s not much more than a placebo, which just simply is not possible or true it just has. It’s very on unique mechanism of action, Several mechanisms of actions actually from what the literature shows and I believe it certainly does have some value in relieving manifestations or deep, internalized “foreboding and possibly existential, dread or thoughts “seems effective for mild or general social anxiety, agoraphobia perhaps even effective in treating both anxiety and depression, it reminds me a little bit of life what we have in the United States the medication Buspar/Buspirone only I would say 100 times more effective than that. This is one of those medication is much like Buspar I’ve seen people all too many times in despair frustration simply say, shaking their heads “It don’t work” understandable because I still very much independent on my rescue medication’s for me being the Clonazepam 0.5mg 3x a day what I know considered to be a God send the Selank I truly have never felt relief of both anxiety and depression, almost simultaneously at the same time as I did with the heavenly Selank, take it short term/take it long-term. Why can’t we just take what makes our quality of life just a little better and a little gentler everything is subjective and different to each patient despite contrary to what doctors and providers going by just really DEA laws at the end of the DEA laws at the end of the day as how I see it but I have been taking the advised recommended daily dosage 100mg (2 50mg capsules 3x a day) I also am intrigued by the literature out on the Grandaxin/Tofisopam it soft being the mildest of mild, but indeed a benzodiazepine, interesting articles and literature out there using that medication as well for the treatment of schizophrenia that is genetic in both me and my biological sisters case both prone to and suffer from seizures, and believe me some of the anti-convulsions out there that are recognized as a standard of treatment generally Depakote and Haldol neurological afflictions that I have have been on the as rough stuff! rough stuff talking about the Depakote/Valproic acid The stomach cramping ringing in the ears, just to name a couple, pretty dreadful side effects just could not tolerate They love to throw that one at you in a given chance I’ve noticed too.”Let’s just a little mood stabilization” Only the side effects with that we’re not so painful really so I gentle effective relief and who on earth could blame you I recognize also the Stresam Really must be taken regularly daily and can take a week or 2 before you begin to see notice results weeks before you begin noticing improvement in symptoms and results, And it’s a little on the costly side $80–$90 But I would say give this a try It has several different mechanisms of action, not only with GABA receptors, but serotonin and a few other different ones as well. Just be sure to do 2 things really your own research and if you have any concerns about drug interactions, you can easily enter in on medication that you are on into a simple CVS Walgreens and various other drug data and interaction banks on different websites and apps and 2 run it by your doctor or nurse practitioner if you are under the care of and 9 times don’t of 10 they are usually quite intrigued themselves and are all on board with it, I mentioned it to my provider just last month regarding the Neuroprotective Peptides and she seemed to have a general basic understanding of what thing are and what they do, This is my review on the Stresam/Etifoxine Best of regards to all and wishing you Peace Love Happiness and Health!! Kind Regards- Justin

Love this for taking the edge off after a stressful day!

Aside from their customer service being wonderful, this product in particular has become mandatory to my nootropic stack. Still experimenting with others, but I’ve actually had some help from this one.

I had never heard of Strezam before, but was looking for anti-anxiety help. I was pleasantly surprised that just one capsule did the trick but didn't make me sleepy. Will definitely repurchase from Cosmic Nootropics!

I’ve been using this off and on for a few months. It’s not as effective as a true benzo but is still helpful to quell anxiety. I’d say it’s about 75% as effective as a benzo. On the other hand, it’s much less addictive according to everything I’ve read about it. That’s why I’m using it.

This is a good product. It was well received from my body and it worked without any side effects.

No side effects at all. Why take anything else? Just wish it was one a day.

It is consistent on how it helped me relax.

Stresam 50 mg seemed to provide roughly equivalent anxiolysis of about 7.5–10 mg diazepam, but minus the hypnotic effects. Hence, I can’t recommend Stresam for sleep (though it may well help; I don’t know). However, I CAN heartily recommend it as a moderately powerful anxiolytic (with less dependence liability than benzodiazepines).

Unfortunately Strezam did not work for me. Any doses any situation- no effects what so ever. 5 stars to the company! Other products are great 👍

I don't think I felt anything. My liver did hurt for a bit when I first took the recommended dose, but it stopped hurting after the 2nd one. Honestly, it did nothing for me. Fortunately, there's other things that do work for me. It wasn't really worth 90$.

Working great for anxiety and haven't noticed any side effects. I was also able to go off of my Zoloft prescription and hopefully can go off of Klonopin prescription as well.

First, these guys are great. Always very responsive during business hours and helpful with orders. Thank you! Second, the Etifoxine is exactly what I needed. I suffer from Post-Finasteride Syndrome, which results in a depletion of Allopregnanolone in the brain. Etifoxine is one of very few compounds in the world that agonize the TSPO receptors, the rate limiting step in the synthesis of Allopregnanolone, to start that natural production of Allopregnanolone again. Allopregnanolone, for context, is the body's natural Xanax/Benzodiazepine that is potent to the GABAA receptors for potentiality the action of tranquility, euphoria, and relaxation in the nervous system and stimulates the release of the neurotransmitter, GABA. It works well. Thank you!

I have not received my order of which I paid a large amount

It caused a moderate sedation the first time I used this medication. I continued at the recommended dose and then developed pale stools and right upper quadrant pain. I threw them in the trash. $200 gone

Both my husband and I have used this product for anxiety. I works wonders! I have not experienced any side effects using this medication.

Heard that this was going off the market. Sad. For my daughter who has high anxiety, this has worked better than anything. If you have to take normal prescription anxiolytics, this would be the closest one. It could help you get off regular benzos as it gives you a close feeling. Anxiety sucks, but having something like this really does help.

I found Strezam to be particularly effective for coping with reduction of or discontinuation of mainline benzodiazepines. In fact, I haven’t found a better recourse for withdrawal symptoms, or even PAWS, then this nootropic. Very grateful for the minds that have made this available to the Western world, where such pharmacological antidotes have not been seriously considered by the FDA. Thank you cosmic once again!