THYMALIN ® (Thymus Extract)
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Thymalin is a polypeptide medicine containing extract of cattle thymus in proportion 10 mg per vial.
This medication induces proliferation and differentiation of T lymphocytes (Thymus-dependent lymphocytes) precursors into mature T cells, stabilizes the T lymphocyte subpopulations ratio, regulates the T- and B- lymphocyte interaction, and activates a phagocytic function in neutrophils, microphages, monocytes, and NK cells (Natural-killer cells).
Thymalin was developed in 1974 from the calf thymus. In 1992, it was registered as an immunomodulator.
Thymalin is recommended for adults and children from six months of age:
- As a part of complex therapy of bacterial and chlamydia infections (in gynaecology and urology);
- As a part of complex therapy of acute and chronic inflammatory infections that are accompanied by impairment of cellular immunity (treatment of osteomyelitis, prostatitis, etc.);
- For preventing the suppression of immunity, hematogenesis and regeneration processes in the post-traumatic and post-operative period (treatment of full-thickness burns and frostbites);
- During radiotherapy or chemotherapy treatment and while taking massive doses of antibiotics (in oncology);
- For prevention and complex treatment of viral infections, including URI (upper respiratory infection) and influenza (treating children with frequent and long-term illnesses).
Here are some more benefits of Thymalin peptide:
- Thymalin is a natural physiological immunostimulant, buy it to stabilize the immune response and regulate the T and B cell ratio. Thymalin has a broader application scope. It can be used in case of immunosuppression of any origin and is compatible with antiviral medication.
- Thymalin is suitable for children aged 6 months or older. The fact that children as young as 6 months of age are allowed to take this medicine proves its safety. When applied in accordance with the dosage regimen, the medication does not cause side reactions and is well tolerated.
- Thymalin produces a mild, natural physiological immunological effect without disturbing (over-stimulating) the immune response. The regeneration enhancement (the second component of the action of Thymalin) provides for better healing time with no side effects.
- The reliability of Thymalin is confirmed by more than 40 years of experience in clinical use.
The results of the clinical use of Thymalin in paediatrics
The clinical observation confirms the safety of thymus medication use in children, including infants.
- Thymus medications can be the drugs of choice, when included in the complex therapy of severe diseases of viral and viral-bacterial etiology in children of any age.
- Thymus medications can be used as monotherapy in children with frequent ARVI (acute respiratory viral infections), especially in children with a history of thymomegaly (thymic hyperplasia).
- Long-term results (up to 17 years of observation) of treatment with thymus medications indicate their protective effect. None of the children during the follow-up period (for 17 years) had repeated pneumonia, relapses of osteomyelitis, sepsis, candidiasis of the skin and mucous membranes, candidal meningitis, or infective endocarditis.
Thymalin in oncology
The use of Thymalin can significantly reduce the frequency of metastasis of malignant tumors by 2.3 times.
Using Thymalin to treat children with chronic gastroduodenitis
Sample: 34 patients with chronic gastroduodenitis aged 10–16 years.
Thymalin treatment significantly reduced the number of hemolyzed cells. The use of Thymalin in treating chronic gastroduodenitis helps alleviate clinical manifestations of the disease and inhibits the processes of excessive lipid peroxidation.
The impact of Thymalin on the cytokine dynamics in children with infective endocarditis
Thymalin treatment provides higher stability of the cytokine level.
The impact of Thymalin on the hemostatic system in patients with urgent and complicated acute appendicitis
The use of Thymalin in combination with standard therapy leads to the stabilization of blood clotting and fibrinolysis and eliminates the manifestations of DIC (disseminated intravascular coagulation).
Using Thymalin to treat children with CLD (chronic lung disease)
Sample: 28 children with CLD (16 with bronchiectasis and 12 with chronic bronchitis deformans).
The use of Thymalin significantly enhances the CLD treatment and stabilizes cellular and humoral immunity.
Buy Thymalin to help reduce the disease duration, restore the immune system and prevent or significantly reduce the likelihood of developing complications!
If you want to read more about thymus peptides read the article
Thymus Peptides in Immunology and Age-Prevention
Produced by Samson Med, Russia.
This product has not been approved by the US FDA. All statements on this page are for informational purposes only and have not been evaluated by the US FDA.
This product is not intended to diagnose, treat, cure, or prevent any disease. See more
Thymalin is a polypeptide medicine containing extract of cattle thymus in proportion 10 mg per bottle.
This medication restores the immune reactivity (by regulating the ratio and interaction of T and B lymphocytes and the subpopulations thereof, stimulating the cellular immunity and enhancing the phagocytosis), prevents the suppression of regeneration and hematogenesis, and enhances cell metabolism.
Dosage and administration
Dilute the content of one bottle in 1-2 ml of isotonic solution of sodium chloride before injection.
The medication is applied intramuscularly daily: dosage for adults is 5–20 mg (a course of 30–100 mg), for infants under 1 year – 1 mg; for 1–3-year-olds – 1.5–2 mg; for 4–6-year-olds – 2-3 mg; for 7–14-year-olds – 3–5 mg over 3–10 days. If necessary, the treatments can be repeated after 1–6 months.
As a prevention, the medication is applied intramuscularly daily, adults 5–10 mg, children 1–5 mg over 3–5 days.
Thymalin is highly compatible with other medicines.
Samson Med, Russia.
- Kuznik et al (1981) Effect of thymalin on blood coagulation and fibrinolysis https://www.ncbi.nlm.nih.gov/pubmed/7286199
- Dekster et al (1984) Clinico-immunologic changes in patients with cervical cancer after treatment with thymalin https://www.ncbi.nlm.nih.gov/pubmed/6608824
- Bakhidze (1985) Use of thymalin in the complex treatment of patients with cancer of the uterus https://www.ncbi.nlm.nih.gov/pubmed/3839953
- Kiselev et al (1985) Effect of thymalin on the function of the blood kallikrein-kinin system in thymectomized rats https://www.ncbi.nlm.nih.gov/pubmed/2990599
- Pastorova et al (1989) Comparative study of the effect of the thymus preparations thymoptin and thymalin on fibrin-monomer polymerization https://www.ncbi.nlm.nih.gov/pubmed/2744143
- Khlystova et al (1989) The dynamics of thymalin localization in human thymus cells in embryogenesis https://www.ncbi.nlm.nih.gov/pubmed/2699438
- Kogosova et al (1990) Effectiveness of administration of thymalin in the complex treatment of pulmonary tuberculosis https://www.ncbi.nlm.nih.gov/pubmed/2080155
- E Bakhidze, J Bokhman (1990) Application of thymic factor “Thymalin” in complex treatment of endometrial cancer patients https://www.ncbi.nlm.nih.gov/pubmed/2245808
- V Iangolenko (1991) The effect of combined therapy with the use of thymalin and piracetam on the level of middle-molecule peptides in the blood and on the lipid peroxidation activity in patients with diffuse toxic goiter https://www.ncbi.nlm.nih.gov/pubmed/1725225
- Chukhlovina et al(1994) The immunomodulating and metabolic actions of thymalin in an experimental herpetic infection https://www.ncbi.nlm.nih.gov/pubmed/7992545
- I Kazantseva, R Bikbulatov (1994) Thymalin in the treatment of herpetic stomatitis in children https://www.ncbi.nlm.nih.gov/pubmed/8191521
- V Morozov, V Khavinson (1997) Natural and synthetic thymic peptides as therapeutics for immune dysfunction https://www.ncbi.nlm.nih.gov/pubmed/9637345
- M Musaev (2001) Comparative study of the effects of thymalin and vitamin E on certain indices for local pulmonary protection in rheumatoid arthritis https://www.ncbi.nlm.nih.gov/pubmed/11692697
- Khlystova et al (2002) Age-related changes of thymalin content in human epidermis https://www.ncbi.nlm.nih.gov/pubmed/12447484
- V Khavinson, V Morozov (2002) Geroprotective effect of thymalin and epithalamin https://www.ncbi.nlm.nih.gov/pubmed/12577695
- V Khavinson, V Morozov (2003) Peptides of pineal gland and thymus prolong human life https://www.ncbi.nlm.nih.gov/pubmed/14523363
- Kuznetsova et al (2013) Comparative study of immunomodulatory activity of peptides, tinrostim and thymalin https://www.ncbi.nlm.nih.gov/pubmed/24734422
- Zhukova et al (2018) Effect of Thymalin on the Tumor and Thymus under Conditions of Activation Therapy In Vivo https://www.ncbi.nlm.nih.gov/pubmed/29797130
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