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VISOMITIN ® (SkQ1 / Skulachev Ions)

33 Reviews

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All statements on this page are for informational purposes only and have not been evaluated by the US FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Before using this product, consulting a qualified MD is mandatory. See more

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Buy Visomitin® SKQ1 Online!

Visomitin® (SkQ1) is a Russian medication with a mitochondria-targeted antioxidant SkQ1 as the active ingredient. It proved to be effective for a wide range of age-related disorders such as cardiovascular diseases, neurodegenerative disorders, and ophthalmic conditions. Visomitin eye drops are used to treat age-related vision degeneration, dry eye syndrome, non-infectious uveitis, cataract, and glaucoma.

 

Save money with the volume discount!

Synonyms SkQ1
Form: Eye drops
Form description: Transparent or slightly opalescent, colorless or slightly colored liquid.
Active ingredient: In 1 ml: plastohinonildetsiltriphenylphosphonium bromide (PDTP) 0.155 mcg.
Excipients: In 1 ml: benzalkonium chloride – 0.1 mg, hypromellose – 2 mg, sodium chloride – 9 mg, sodium dihydrogen phosphate dihydrate – 0.81 mg, sodium hydrogen phosphate dodecahydrate – 1.16 mg, sodium hydroxide 1M solution – up to pH 6–8, purified water – up to 1 ml.
СAS Number: 934826-68-3
ATC code: S01XA
Pharmacological action: Keratoprotective
Shelf life: 2 years. Do not use it beyond the expiration date printed on the package.
Storage conditions: Store in a dry dark place at temperatures no higher than 2-8°C (35.6-46.4°F). Use the opened bottle within 1 month. Keep it in a safe place out of reach of children.
Terms of release: Over-the-counter
Manufacturer: Mitotech, Russia https://sk-q.com/

What is Visomitin?

The active substance of Visomitin is SkQ1. It is a small molecule synthesized by Professor V. Skulachev at his team at Moscow State University. One part of SkQ1 acts as a molecular “tow truck” carrying the other part of the molecule – an extremely active antioxidant plastoquinone – into mitochondria. The physics of the mitochondrial membrane and unique properties of SkQ1 direct it into the inner leaflet of the inner mitochondrial membrane with high accuracy.

The presence of SkQ1 in the mitochondrial membrane enables mitochondria to protect themselves from reactive oxygen species (ROS) by breaking the chain reaction of lipid destruction. This ability of the lead molecule to protect cells against oxidative stress is the key to treating patients with various age-related disorders such as cardiovascular diseases, neurodegenerative disorders, and ophthalmic conditions.

What Does Visomitin Do?

It has been hypothesized that age-dependent accumulation of oxidative damage in living organisms may be the main cause of the aging process. It is possible to control this damage accumulation by controlling the level of ROS production in mitochondria. It is important to stress that ROS production shall only be controlled but not stopped, so that ROS can still fulfill a number of crucial biological functions, for instance, fighting bacteria and viruses.

According to Dr. Skulachev, a “perfect” antioxidant shall be specifically targeted to mitochondria where ROS are produced. And it shall effectively remove excessive ROS. The antioxidant must be non-toxic and it must not be recognized and eliminated by cell enzymes. If these criteria are fulfilled, the “perfect” antioxidant compound can prevent/repair oxidative damage and prevent/treat many age-related disorders across various therapeutic areas.

The mechanism of action of SkQ1 involves at least two extremely complex and novel concepts: 1) delivering a compound inside mitochondria and 2) reducing ROS production inside mitochondria in a controlled and sustainable manner. SkQ1 molecule successfully addresses these two aspects as experiments show.

What are the Intended Uses of Visomitin?

More than a dozen studies have been conducted and showed SkQ1 effectiveness in such critical therapeutic areas as:

  • Age-related macular degeneration (AMD);
  • Dry eye syndrome (DES);
  • Non-infectious uveitis;
  • Cataract;
  • Glaucoma.

Where Can I Order Visomitin (SkQ1) Online?

You can order Visomitin online from different vendors. CosmicNootropic offers Visomitin in the form of eye drops with worldwide shipping! Always be sure to do your research before purchasing any nootropic supplement to ensure you are getting a quality product.

You can order Visomitin and get it delivered to the USA, Europe, the UK, Asia, and many other destinations via CosmicNootropic.

 

Also, try other SkQ1 revolutionary products!

 

What is Visomitin Dosage, Administration?

Dosage is 1-2 drops 3 times a day. Duration of treatment is determined by the ophthalmologist individually, depending on the severity of symptoms and the dynamics of the pathological process in the eyes. The average treatment period is two to six months.

During complex treatment of senile cataract it is recommended to hold regular medical examinations by ophthalmologist.

Visomitin Contraindications

Using Visomitin eye drops is contraindicated in case of individual intolerance or hypersensitivity to the active ingredient and auxiliary ingredients. Also, the drug cannot be used by children under 18 years old.

What are the Side Effects of Visomitin?

Local adverse reactions in the eye can develop in the form of a burning sensation, cramps, redness of the conjunctiva, etc.

Rare side effects: systemic allergic reactions such as skin rashes, itching, urticaria (a characteristic rash and swelling which in appearance resemble the sting).

Cases of severe allergic reactions in the form of angioedema, or anaphylactic shock have not been reported.

Note: The product shall be kept in the fridge.

 

OFFICIAL INSTRUCTION

    1. Krementsova et al (2012) Reproducible effects of the mitochondria-targeted plastoquinone derivative SkQ1 on Drosophila melanogaster lifespan under different experimental scenarios https://www.ncbi.nlm.nih.gov/pubmed/23073710
    2. Kolosova et al (2012) The mitochondria-targeted antioxidant SkQ1 but not N-acetylcysteine reverses aging-related biomarkers in rats https://www.ncbi.nlm.nih.gov/pubmed/23104863
    3. Ilyasova et al (2012) Substitution of ether linkage for ester bond in phospholipids increases permeability of bilayer lipid membrane for SkQ1-type penetrating cations https://www.ncbi.nlm.nih.gov/pubmed/23157264
    4. Chistyakov et al (2012) Effect of plastoquinone derivative 10-(6′-plastoquinonyl) decyltriphenylphosphonium (SkQ1) on estrous cycle and 17β-estradiol level in rats https://www.ncbi.nlm.nih.gov/pubmed/23244734
    5. Snytnikova et al (2012) The therapeutic effect of mitochondria-targeted antioxidant SkQ1 and Cistanche deserticola is associated with increased levels of tryptophan and kynurenine in the rat lens https://www.ncbi.nlm.nih.gov/pubmed/23288574
    6. Solovieva et al (2013) Effect of mitochondria-targeted antioxidant SkQ1 on programmed cell death induced by viral proteins in tobacco plants https://www.ncbi.nlm.nih.gov/pubmed/24228922
    7. Kapay et al (2013) Mitochondria-targeted plastoquinone antioxidant SkQ1 prevents amyloid-β-induced impairment of long-term potentiation in rat hippocampal slices https://www.ncbi.nlm.nih.gov/pubmed/23735258
    8. Stefanova et al (2014) Alzheimer’s disease-like pathology in senescence-accelerated OXYS rats can be partially retarded with mitochondria-targeted antioxidant SkQ1 https://www.ncbi.nlm.nih.gov/pubmed/24047616
    9. Vays et al (2014) Antioxidant SkQ1 delays sarcopenia-associated damage of mitochondrial ultrastructure https://www.ncbi.nlm.nih.gov/pubmed/24519884
    10. Perepechaeva et al (2014) The Mitochondria-Targeted Antioxidant SkQ1 Downregulates Aryl Hydrocarbon Receptor-Dependent Genes in the Retina of OXYS Rats with AMD-Like Retinopathy https://www.ncbi.nlm.nih.gov/pubmed/25132985
    11. Muraleva et al (2014) The mitochondria-targeted antioxidant SkQ1 restores αB-crystallin expression and protects against AMD-like retinopathy in OXYS rats https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614531/
    12. Novikova et al (2014) Preventive and therapeutic effects of SkQ1-containing Visomitin eye drops against light-induced retinal degeneration https://www.ncbi.nlm.nih.gov/pubmed/25519068
    13. Rogovin et al (2014) Mitochondria-Targeted Antioxidant SkQ1 Accelerates Maturation in Campbell Dwarf Hamsters (Phodopus campbelli) https://www.researchgate.net/publication/266980940_Mitochondria-Targeted_Antioxidant_SkQ1_Accelerates_Maturation_in_Campbell_Dwarf_Hamsters_Phodopus_campbelli
    14. Rogovin et al (2014) Effects of mitochondria-targeted plastoquinone derivative antioxidant (SkQ1) on demography of free-breeding Campbell dwarf hamsters (Phodopus campbelli) kept in outdoor conditions. reproduction and lifespan: explanation in the framework of ultimate loads https://www.ncbi.nlm.nih.gov/pubmed/25519070
    15. Myasoedova et al (2014) Therapeutic Doses of SkQ1 Do Not Induce Cytochromes P450 in Rat Liver https://www.researchgate.net/publication/269771479_Therapeutic_Doses_of_SkQ1_Do_Not_Induce_Cytochromes_P450_in_Rat_Liver
    16. Manskikh et al (2014) Effect of the mitochondria-targeted antioxidant SkQ1 on development of spontaneous tumors in BALB/c mice https://www.ncbi.nlm.nih.gov/pubmed/25519073
    17. Iomdina et al (2015) Mitochondria-targeted antioxidant SkQ1 reverses glaucomatous lesions in rabbits https://www.ncbi.nlm.nih.gov/pubmed/25553485
    18. V Samuilov, D Kiselevsky (2015) Effect of cationic plastoquinone SkQ1 on electron transfer reactions in chloroplasts and mitochondria from pea seedlings https://www.ncbi.nlm.nih.gov/pubmed/25869358
    19. Rumyantseva et al (2015) Ameliorative effects of SkQ1 eye drops on cataractogenesis in senescence-accelerated OXYS rats https://www.ncbi.nlm.nih.gov/pubmed/25267419
    20. Manskikh et al (2015) Age-associated murine cardiac lesions are attenuated by the mitochondria-targeted antioxidant SkQ1 https://www.ncbi.nlm.nih.gov/pubmed/25323729
    21. Weniger et al (2016) The Analgesic Effect of the Mitochondria-Targeted Antioxidant SkQ1 in Pancreatic Inflammation https://wwww.unboundmedicine.com/medline/citation/27274778/The_Analgesic_Effect_of_the_Mitochondria_Targeted_Antioxidant_SkQ1_in_Pancreatic_Inflammation
    22. Bazhin et al (2016) The novel mitochondria-targeted antioxidant SkQ1 modulates angiogenesis and inflammatory micromilieu in a murine orthotopic model of pancreatic cancer https://www.ncbi.nlm.nih.gov/pubmed/26914404
    23. Bakeeva et al (2016) Mitochondria-targeted antioxidant SkQ1 reduces age-related alterations in the ultrastructure of the lacrimal gland https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348314/
    24. Petrov et al (2016) SkQ1 Ophthalmic Solution for Dry Eye Treatment: Results of a Phase 2 Safety and Efficacy Clinical Study in the Environment and During Challenge in the Controlled Adverse Environment Model https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735228/
    25. Tsybulko et al (2016) The Mitochondria-Targeted Plastoquinone–Derivative SkQ1 Promotes Health and Increases Drosophila melanogaster Longevity in Various Environments https://academic.oup.com/biomedgerontology/article/72/4/499/2630002
    26. Zernii et al (2017) Mitochondria-Targeted Antioxidant SkQ1 Prevents Anesthesia-Induced Dry Eye Syndrome https://www.researchgate.net/publication/320369542_Mitochondria-Targeted_Antioxidant_SkQ1_Prevents_Anesthesia-Induced_Dry_Eye_Syndrome
    27. Rademann et al (2017) Mitochondria-Targeted Antioxidants SkQ1 and MitoTEMPO Failed to Exert a Long-Term Beneficial Effect in Murine Polymicrobial Sepsis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625755/
    28. Titova et al (2018) Mitochondria-targeted antioxidant SkQ1 suppresses fibrosarcoma and rhabdomyosarcoma tumour cell growth https://www.ncbi.nlm.nih.gov/pubmed/29995559
    29. Jiang et al (2018) Mitochondria-targeted antioxidant SkQ1 improves spermatogenesis in Immp2l mutant mice https://www.ncbi.nlm.nih.gov/pubmed/28703400
    30. Rogov et al (2018) New Data on Effects of SkQ1 and SkQT1 on Rat Liver Mitochondria and Yeast Cells https://www.ncbi.nlm.nih.gov/pubmed/29738689
    31. Zernii et al (2018) Mitochondria-targeted antioxidant SKQ1 protects cornea from oxidative damage induced by ultraviolet irradiation and mechanical injury https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12886-018-0996-7
    32. Wei et al (2019) The Role of SKQ1 (Visomitin) in Inflammation and Wound Healing of the Ocular Surface https://pubmed.ncbi.nlm.nih.gov/30565203/
    33. Dvoretskaya et al (2021) Mitochondrial Antioxidant SkQ1 Has a Beneficial Effect in Experimental Diabetes as Based on the Analysis of Expression of microRNAs and mRNAs for the Oxidative Metabolism Regulators https://pubmed.ncbi.nlm.nih.gov/34829620/
    34. Rudnitskaya et al (2022) Changes in Glial Support of the Hippocampus during the Development of an Alzheimer’s Disease-like Pathology and Their Correction by Mitochondria-Targeted Antioxidant SkQ1 https://pubmed.ncbi.nlm.nih.gov/35163053/
    35. Song et al (2022) Mitochondrial Targeted Antioxidant SKQ1 Ameliorates Acute Kidney Injury by Inhibiting Ferroptosis https://pubmed.ncbi.nlm.nih.gov/36193064/

5

Based on 33 Reviews

(32)

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07/14/2024

Justine E.

Justine E.

 Verified Buyer
US

US

Buy these

I bought these following a dr.s advice and glad I did. It's great these are not a steroid and help with the health of the eye and any dryness. Tha ks you to the wonderful docyors and scientists who developed these drops. And for this company for selling them

07/16/2024

Hi Justine! Thank you for sharing your experience! We're thrilled to hear that you followed your doctor's advice and found our eye drops beneficial. It's reassuring to know they've helped with eye health and dryness without being a steroid. We're grateful to the doctors and scientists who developed these drops and proud to offer them. Your appreciation means a lot to us, and we're committed to providing products that meet your health needs.

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0

05/23/2024

Alisha H.

Alisha H.

 Verified Buyer
US

US

Great customer service

Very impressive, great customer service. Easy to get a hold of and quick to respond

05/24/2024

Hi Alisha! Thank you so much for your kind words, they mean a lot to us! We are beyond happy to hear that you are satisfied with our service :)

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0

03/22/2024

stephen s.

stephen s.

 Verified Buyer
US

US

good stuff so far

03/22/2024

Hi Stephen! Thank you for your review :)

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0

03/15/2024

Alisha H.

Alisha H.

 Verified Buyer
US

US

Not received

I still have not received my order, it’s been a long time

03/15/2024

Hi Alisha! We are so sorry that you never received your order. We have contacted you via email to sort this situation out.

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0

02/02/2024

Regis M.

Regis M.

 Verified Buyer
US

US

Visomitin is great stuff

I've used this product regularly for a couple of years now. Feel like it really helps improve vision and keep eyes lubricated. Just wish it was made somewhere in the US. Glad Cosmic is willing to be the intermediary with the Russian manufacturers, but it would be better if there was a domestic source.

02/04/2024

Dear Regis, We're glad to know that Visomitin helps you. We specialize in russian nootropics, that's why we do not sell products from the US suppliers. And frankly, the industry is not well developed there yet.

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0

01/19/2024

Tatiana E.

Tatiana E.

 Verified Buyer
US

US

Great product, Awesome company

Superb ease and smooth all purchasing, overseas shipping, 100% support is available Using this company for man years Highly recomended Thank you

01/20/2024

Hi Tatiana! Thank you so much for your kind words, they mean the world to us :)

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0

11/24/2023

Alex Y.

Alex Y.

 Verified Buyer
US

US

Timely Delivery of Product as Advertised

Good communication through the purchase process

12/14/2023

Dear Alex, we're thrilled to know you're satisfied with our service! Looking forward to seeing you as our client again soon.

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0

10/23/2023

robert s.

robert s.

 Verified Buyer
US

US

still hasn't arrived.

10/25/2023

Dear Robert, we have contacted you about this issue. Could you please check your email?

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0

08/23/2023

Brooke R.

Brooke R.

 Verified Buyer
US

US

Quality, fast delivery and perfect product !

I got this product for my son's Uveitis. We have used several bottles and I will order more when he runs out. He had expressed his results with his vision and I hope it kills the parasite and heals deterioration of his eyesight. So far so good, for the last few years of use !

08/23/2023

Hi Brooke! Thank you for finding a moment to leave a review. We're beyond happy to know that our product helped your son!

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0

06/06/2023

Norman S.

Norman S.

 Verified Buyer
US

US

Great

Great products and service

06/07/2023

Hi Norman, thank you for your kind feedback! We're thrilled to hear that you are satisfied with our products and service.

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0

01/23/2023

Shawn V.

Shawn V.

 Verified Buyer
US

US

Great product! My eyes feel more clear and continue to heal VISOMITIN

I have used Visomitin drops for nearly one month. My eyes are feeling healthier and I hope this improves my vision over time. I will continue tis product for another 30 days. Thank you Cosmicnootropic for your help and excellent customer service throughout the shipping process!

01/25/2023

Hi Shawn! Thank you very much for sharing your experience! We're happy that you're satisfied with Visomitin and with our service. 💙

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1

11/03/2022

Shiloh L.

Shiloh L.

 Verified Buyer
US

US

Eye Drops

I'm being proactive since cataracts and AMD run in my family.

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0

02/21/2022

ANTHONY H.

ANTHONY H.

 Verified Buyer
AU

AU

EYE PRESSURE

So Far so good eye pressure seems lower no pain or discomfort in the eyes just finished the first bottle will use for six months

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0

02/16/2022

Diana P.

Diana P.

 Verified Buyer
US

US

Eye improvement

The drops are for the long run - they should repair the oxidative damage done to the retina over years. I hope to improve my slightly blurry vision. The research is solid, I expect to be using these for a few months before seeing results.

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0

11/15/2021

Renja B.

Renja B.

 Verified Buyer
LU

LU

Great help for dry eyes & super customer service!

Great help for dry eyes & super customer service!

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0

09/29/2021

Eric W.

Eric W.

 Verified Buyer
US

US

VISOMITIN

I really like these eye drops. I am a repeat customer.

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0

07/16/2021

Christopher C.

Christopher C.

 Verified Buyer
US

US

Great product and service

Extremely impressed with this product which I use to treat post-laser surgery dry eye. I also found the service to be professional and the shipping was fast -- less than 2 weeks. Will be ordering more. Thanks!

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0

06/03/2021

Yevgeny K.

Yevgeny K.

 Verified Buyer
US

US

difficult to receive

Everything is fine if one is able to receive the package. I am still waiting for it.

06/30/2021

Hi Yevgeny, we are sorry for the bad experience. Please reach out to [email protected] and we will sort this out.

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1

05/09/2021

Douglas C.

Douglas C.

 Verified Buyer
US

US

Unfortunately I still have not received the product.

05/26/2021

Hi Douglas, please reach out to [email protected] so we can help you out

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1

05/02/2021

Jon S.

Jon S.

 Verified Buyer
US

US

SkQ1 Eye Drops

I ordered the SKQ1 Eye Drops in February, and I have still not received them! I am still waiting for them to arrive! Any help in locating and expediting them would be very appreciated. Jon Steele 310 18th Street Huntington Beach, CA 92648 [email protected] 949.378.7695

05/26/2021

Hi Jon, This is a long time indeed. Please reach out to [email protected] so we can figure something out.

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1
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4 years ago

Review

Brandon B. Verified Buyer

Yeah, just eye drops, then...

So the eye drops are nice, especially because I keep them in the fridge. They make my eyes feel refreshed and hydrated. Then on my 5th day of taking 2 drops/eye twice a day, it happened...I was shaving and looked into the mirror and could see details I have never could see before. Never knew I was that ****, but my eyes are sharper than ever. Truly amazing product that increases overall eye health & function. Ordered 3 more bottles and will continue the same regimin until my wife looks ****, then stop. Thanks.

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