AFOBAZOLE [Fabomotizole]

$9.00

AFOBAZOLE stabilises and upregulates GABA and benzodiazepine receptors, exhibits neuroprotective properties, and diminishes anxiety and tensions in the body. The drug is designed above all for people with asthenic personal traits such as emotional lability, e.g. tendency to react emotionally in stressful situations.  

Availability: in stock

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Aralia Tincture

$5.90

Aralia is a well-known gentle adaptogenic tonic herb popular for its wide range of pharmacological properties. It is used to treat physical and mental fatigue, asthenic syndrome, arterial hypotension, decreased sex drive, mental breakdown, depression, enuresis, radiation sickness and metabolic disorders. This herbal remedy can also help to recover from craniocerebral injury, contusion, meningitis, post-infectious arachnoiditis and ARVI (in the complex therapy). 

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BEMITIL [Metaprot]

$10.00

Developed in the Soviet Union for the needs of the military, Bemitil (also known as Metaprot and AntiHot) has a long history of usage in clinical practice and in sport. It was developed in the 1970s and was successfully used during Afghanistan war, Chernobyl catastrophe and Olympic games in Moscow.

The drug has nootropic, regenerative, antihypoxic, antioxidant and immunomodulatory action.

A perfect alternative for the discontinued Ladasten (Bromantane)

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CEREBROLYSIN®

$40.00

Cerebrolysin ® is a neurometabolic stimulator based on neuropeptides (20%) and amino acids (80%) isolated from pig brain proteins. Unlike the majority of peptide drugs, Cerebrolysin ® has all the amino acids which compose the central nervous system; this can explain many additional positive properties of Cerebrolysin ®.  

IT CAN BE KEPT OUTSIDE OF REFRIGERATOR WITH TEMPERATURE BELOW 25 ℃ (77.00 ℉)

Fast Domestic shipping available! 🇺🇸

Availability: in stock

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CERETON ® [Alpha-GPC]

$11.00

Cereton® is the most efficient cholinergic supplement in terms of increasing brain concentration of choline. In the brain, choline and its metabolites are needed for the cholinergic neurotransmission - the process of communication between neurons. Increasing phosphatidylcholine and acetylcholine as a result of taking Alpha-GPC might improve certain cognitive functions, including memory retention, focus, and neuroplasticity.

Availability: in stock

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CYTAMINS [NATURAL PEPTIDES]

$14.00

CYTAMINS are proteins, nucleoproteins and minerals isolated from organs of pigs and calves less than 12 months old. These peptide regulators are completely safe supplements that have been used for anti-ageing purposes and also as an aid to conventional treatment methods.

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CYTOGENS [SYNTHESIZED PEPTIDES]

$35.00

CYTOGENS (SYNTHESIZED PEPTIDES) are physiologically active short peptides; they are synthesized combinations of 2-3 amino acids. Cytogens have a faster action compared to extract peptides - CYTOMAX peptides. By reducing peptide deficiency within organs and restoring protein synthesis, Cytogens regulate work and functionality of organs and slow down the ageing process. These peptides can be easily combined with other supplements and medicines and should be used in addition to conventional medical treatment.

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CYTOMAXES [NATURAL PEPTIDES]

$109.00

CYTOMAXES [NATURAL PEPTIDES] is a group of peptides of less than 50 amino acids and with a molecular mass of less than 5 kDa, free from foreign DNA or protein substance, extracted from organs and tissues of young calves by a patented method of thorough filtering. 5 kDa is very little. The molecular mass of DNA fragments and proteinaceous infectious particles, the prions, are several times bigger than that. Therefore these peptide supplements are extremely clean products. They do not have any immunogenic or mutagenic properties.

Peptide bioregulators are shorter than proteins and can be absorbed via the digestive system. They have been shown to shortcut the protein synthesis process by interacting directly with cell DNA - meaning that organs can build and repair tissues easier and quicker when peptide bioregulators are active.

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Eleuthero liquid extract (Siberian ginseng)

$5.90

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ENERION ® [Sulbutiamine]

$9.00 $17.00

ENERION ® is a modified thiamine (vitamin B1), that can easily cross the blood-brain barrier. In the brain, it produces both GABA and acetylcholine, thus affecting adaptability, mood and focus.

Availability: in stock

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ENTROP (PHENOTROPIL) [Phenylpiracetam]

$36.00

Phenotropil ® is a phenyl - derivative of Piracetam. It is reported to be more neuroprotective than the original compound; it was also shown to possess psychostimulatory and various adaptogenic properties.

Entrop ® is a pharmaceutical product with the same active ingredient, phenylpiracetam and it is produced by a Latvian company, Olainfarm.

Availability: Very limited availability

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EXOMITIN (Skulachev Ions | SKQ1 regenerating antioxidant hydrogel)

$25.00

Exomitin is designed for skin damages and problems, including burns and scars. Due to its innovative formula, the mitochondrial antioxidant SkQ1 protects and soothes the skin in case of different types of irritation, redness and dryness. In equal measure Exomitin improves the skin health, restores its regenerative functions, accelerates tissue repair; it also increases antioxidant defense of skin cells. The use of hydrogel provides proper skin care and improves skin resistance to adverse environmental factors.

The mitochondrial antioxidant SkQ1 (“Skulachev's Quinone”) is based on plastoquinone (a substance extracted from the most oxygenated place in the wild - chloroplast of the plants). It is clinically proven that SkQ1 reduces the free radicals activity in the mitochondria at the cellular level and therefore interrupts the aging program. After all, it is toxic forms of oxygen produced by mitochondria that trigger the process of programmed skin cells death (keratinocytes and fibroblasts apoptosis).

Due to its unique properties, the effectiveness of the SkQ1 antioxidant is 1000 times greater than that of the other well-known antioxidants, including famous coenzyme Q10. You can notice a pronounced effect already after the first application of the hydrogel.  Exomitin is suitable for a long-term use and can be mixed with other skin care products.

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Ginseng Tincture (Panax ginseng)

$5.90

Ginseng or Panax is one of the most popular and widely-researched herbal remedies in the world. It is even believed to be a natural cure-all and can be used for a wide variety of purposes, such as low mood and decreased mental capacity. The short list of indications for its use includes: physical and mental fatigue, arterial hypotension, asthenic syndrome, nervous breakdown, sexual dysfunction, neurocirculatory dystonia (hypotonic type) and protracted recovery period after a number of diseases (incl. infections). 

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Leuzea-P (Rhaponticum carthamoides or Maral root)

$6.90

Leuzea (Rhaponticum) has been used in traditional Siberian medicine to bolster both physical and mental performance (especially after illness). The major requirement associated with Leuzea is the enhancement of physical strength and muscle protein synthesis. The other indications for use include mental and physical fatigue, asthenia, exhaustion, decreased mental and physical capacity, irritability, headache, chronic alcoholism, erectile dysfunction.

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MEMANTALE [Memantine]

$9.00

Synthesised by Eli Lilly and Company in 1968, Memantine is one of the few pharmaceuticals approved by the FDA for the treatment of moderate to severe Alzheimer's disease. Off-label use of Memantine also includes reversing tolerance for caffeine, nicotine and opioids; it may also be taken for a treatment of generalised anxiety disorder. 

Memantine reduces certain types of brain activity by binding to NMDA receptors and blocking the activity of glutamate. As a result, Memantine upregulates receptors in the brain and has a cognitive-enhancing effect.

Availability: in stock

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MEXIDOL ®

$7.00

The development of Mexidol ®  is closely related to Soviet chemist Semenov N.N, who was awarded with the Nobel Prize in Chemistry for his piece of research on free radicals in 1956. His research was the basis for understanding of the oxidative stress and means to combat it. It also contributed to the development of drugs with antioxidant and anti-ischemic effects, one of which was Mexidol ®.

Mexidol ® has the following effects: anti-ischemic, anti-hypoxic, neuroprotective, and anxiolytic. Many people report strong anxiolytic effects developed during the course of treatment with Mexidol ®.

Availability: in stock

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MILDRONATE ® [Meldonium]

$7.00

Mildronate ® is used to treat angina, myocardial failure and reduce alcohol withdrawal symptoms. Off-label use of Meldonuim in otherwise healthy individuals includes increasing exercise tolerance, learning, memory, and sexual function.

Mildronate gained popularity after Maria Sharapova, a famous tennis player, said that she has been taking this drug for the last 10 years because of health reasons. Also, a number of other world and Olympic champions were tested positive for it. As of January 2016, this compound has been banned by WADA and may not be used by athletes anymore.

We recommend you this video explanation of Mildronate's effect in the cell.

Availability: in stock

A perfect alternative for the discontinued Ladasten (Bromantane)

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MitoVitan® (Skulachev Ions | SKQ1 anti-aging serum)

$89.00

MitoVitan is a completely new approach in interrupting the biological mechanism of aging. It disables the aging program at the cellular level and helps to maintain the youthfulness of the skin. Daily use of the serum prevents the formation of deep and mimic wrinkles, reduces the visibility of already existing ones and restores natural moisture balance and elasticity of the skin.

The active substance of MitoVitan is an innovative directional antioxidant SkQ1 (Skulachev's Quinone). In contrast to the common nondirectional antioxidants “Skulachev Ions” are sent directly to the mitochondria and reduce the free radicals activity at the cellular level, therefore interrupting the aging program. Due to its unique properties the effectiveness of the SkQ1 is 1000 times greater than that of the other well-known antioxidants, including famous coenzyme Q10.

The essential advantage of MitoVitan serum is its light structure, so that it is quickly absorbed and is invisible on the skin.

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MitoVitan® Active (Skulachev Ions | SKQ1 anti-aging concentrate)

$45.00

MitoVitan Active or SKQ1 (Skulachev Ions) mitochondrial antioxidant concentrate.

MitoVitan Active is an aging intervention concentrate based on innovative directional antioxidant SkQ1 (Skulachev's Quinone). In contrast to the common nondirectional antioxidants “Skulachev Ions” are sent directly to the mitochondria and reduce the free radicals activity at the cellular level, therefore interrupting the aging program. Due to its unique properties the effectiveness of the SkQ1 is 1000 times greater than that of the other well-known antioxidants, including famous coenzyme Q10.

The essential advantage of MitoVitan Active concentrate is a personal approach. Every person is unique, each of us has different skin type and therefore we need different skin care. Thus, just take your favourite cream, serum or any other remedy, add several drops of MitoVitan Active, and here you are: you get your own cosmetic line!  

MitoVitan Active in available in two formats:

• Solo (one 8 ml vial of the concentrate),
• Set (two 8 ml vials of the concentrate; Mito-jar and Mito-spoon for use with thick cosmetic means, and Mito- vial for creating compositions with liquid cosmetic products).

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NOOPEPT ®

$7.00

Noopept ® exhibits effects that are physiological to the human body, as they are based on the formation of active compound cyclopropyl glycine, which is naturally occurring in the brain. Noopept ® increases alpha/beta1 brain wave activity, with 30-minutes latency and 40-minutes duration in all brain areas, which can explain many of its effects. Unlike many other pharmaceuticals, Noopept ® can be officially used for healthy individuals, who want to optimise their mental performance.

Availability: in stock

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NOOTROPIL ® [Piracetam, Lucetam]

$8.00

 It has been more than 40 years since Cornelia E. Giurgea - a Romanian chemist - synthesised a compound which was "capable of selectively influencing integrative mechanisms of the brain”. This chemical compound was Piracetam, which later appeared on the market under the brand name Nootropil ®, simultaneously giving birth to a whole range of pharmaceuticals which we now call nootropics.

Availability: in stock

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PANTOGAM ACTIVE ® [D,L-hopantenic acid]

$9.00

The main substance of Pantogam Active® is a hopantenic acid developed in Japan in 1950. The hopantenic acid combines GABA and vitamin B5 that allows GABA to reach neurons of the central nervous system.

Pantogam Active® is a racemic mix of equal quantities of hopantenic acid and its S-isomer. An isomer presence improves a transport and interaction of the drug with GABA receptor.  GABA is the chief inhibitory neurotransmitter in the mammalian central nervous system. It plays the principal role in reducing neuronal excitability throughout the nervous system. Pantogam Active stabilizes neurotransmitters, i.e. makes them more resistant to temporary or permanent negative effects. 

Availability: in stock

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PHENIBUT ®

$9.00

Phenibut ® is a derivative of the naturally occurring inhibitory neurotransmitter GABA, which can cross the blood-brain barrier much better than the original compound. Unlike usual tranqualizers, Phenibut ® has both psychostimulating and anxiety reducing effects.

Availability: limited availability

The product is available from different manufactures.

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PICAMILON ® [Nicotinoyl-GABA]

$7.00

Picamilon ® is based on a synthetic combination of GABA and niacin, with the former being responsible for reducing neuronal excitability and the latter acting as a strong vasodilator.

Its effects are similar to those of Phenibut, as both drugs reduce anxiety and improve mood. However, unlike Phenibut, Picamilon ® has a much stronger impact on energy metabolism in the brain because it stimulates consumption of oxygen and glucose by neuronal tissue.

Availability: in stock

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PRAMISTAR ® [Pramiracetam]

$25.00

Chemically very similar to Choline, Pramiracetam causes the formation of nitric oxide, a powerful vasodilator, which is crucial for short-term memory. It also affects neuropeptide mediation; as a result, it improves memory and learning processes.

Limited Availability

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Rhodiola Rosea extract (Golden Root)

$9.00

Rhodiola Rosea has been used in traditional medicine for over a thousand years. The "Golden Root" is likely to be one of the most popular herbal adaptogens, second only to Panax Ginseng. It enhances physical work capacity, increases resistance to stress and improves memory without disturbing normal biological functions. Other potential indications for use of Rhodiola include asthenia, increased fatigability, protracted recovery from somatic and infectious diseases, mental and physical exhaustion, neurasthenia and arterial hypotension.

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Schisandra Chinensis Seeds Tincture

$5.90

Known since ancient times for its unique adaptogenic qualities, Schisandra Chinensis can treat various diseases and restore health after severe illnesses. The benefits of this herb have been proved in numerous studies showing that it is one the strongest natural antioxidants in the world. Schisandra will rejuvenate the body, increase the vital energy, enhance physical work capacity and strengthen stress resistance. Some indications for use include asthenic syndrome, chronic fatigue, in combination therapy for treating sexual dysfunction caused by neurasthenia, mental and physical exhaustion, neurocirculatory dystonia (hypotonic type) and protracted recovery from somatic and infectious diseases. 

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SELANK ® 0.15%

$19.50

Selank® 0.15% is an anxiolytic peptide drug with nootropic properties. By its structure, Selank is based on endogenous tetrapeptide Tuftsin, which plays an important role in immune system. To slow the breakdown of peptide and prolong its effects, the inventors of Selank added a Glyproline to its structure.

Tafcin was found to have anxiolytic effects in 1995 and over the next decade Russian scientists were focusing on developing a peptide drug that was able to have the most pronounced anxiolytic effects. This research, as well as clinical trials lasted until 2009, when Selank was finally brought to market under the brand name Selank® 0.15%. It is produced on a GMP-compliant factory by Peptogen Inc. 

The spectrum of pharmacological action of the drug is unique. It is a popular over-the-counter anti-anxiety medicine with antidepressant and anti-asthenic actions; it also has a capacity to enhance memory and cognitive functions. 

The mechanism of anxiolytic action is related to the regulation of norepinephrine, serotonin and enkephalins levels and their metabolism in the brain. It is suggested that another possible mechanism of action is inhibition of enkephalin-degrading enzymes, which increases the activity of endogenous opioid system and explains the mild analgesic effect of Selank.

Numerous clinical trials confirmed the safety of this peptide, which was found to not form a dependence and to be non-toxic even in doses 200-500 times higher than therapeutic ones.

Primary Uses of Selank® 0.15%:

• Anxiety and adjustment disorders;
• Neurasthenia, emotional lability;
• Stress-related disorders.

Is Selank going to be degraded after a long journey from Russia to the US?

• In short, No. It is a pharmaceutical nootropic produced by Peptogen Inc. According to the official instruction (drug sheet), once opened a bottle of Selank® is to be kept at temperatures below 30°C (86°F) for a period of up to 30 days. Apart from that, we want to stress some other points:
• The product contains methylparaben (0.01%), which works as a preservative and ensures longer shelf-life. It is considered safe and is frequently used in other drugs.
• The product is sterile and is produced on a GMP-compliant factory, which is likely to increase storage duration.
• For longer periods of time, Selank should be stored at temperatures below 10°C (50°F). The shelf life of a new product is 2 years if stored below 10°C (50°F).

This implies that if the temperature between 10°C (50°F) to 30°C (86°F) the storage duration is anywhere between 30 days to 2 years, depending on the temperature.

*Up until now, nobody complained about Selank being unusable due to the heat during transportation, though we have been shipping for more than three years by now.

Dosage and Administration

One bottle of Selank contains 60 drops, each having 75 mcg of the active ingredient. The average dose is 2-3 drops in each nostril. Selank should be taken up to 3 times per day.

On-label regimen of Selank is 3 times a day, 2 drops in each nostril, for a period of 14 days. 

Side Effects

Irritation of the nasal mucosa and very rare allergic reactions.

Interaction With Other Drugs

Selank has no effect on depressants or stimulants including Haloperidol, Pentobarbital, Hexobarbital and analeptics. It can be combined with psychotherapy. It is safe to use with ethanol containing substances.

Overdose

Selank was shown to be completely safe even when hundredfold doses were administered.

Storage

Keep in a dark place at a temperature less than 10°C (50°F) for up to two years.

Note: If there is a need to increase the effect of Selank, a second dose should be taken 15-minutes after the first one. 

Manufacture Contact Details: http://peptogen.ru, Moscow, Russia

Email: info@drugsafety.ru 

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SEMAX®

$15.90

Semax® is a Russian nootropic drug that is used as nasal drops to improve cognitive functions and treat various medical conditions. By its structure, Semax® is a fragment of endogenous neuropeptide ACTH. The drug was shown to increase BDNF that is responsible for the growth and differentiation of new neurons and synapses.

The positive effects of neuropeptides were discovered in the late 1960s when D. de Vid - who coined the term neuropeptide - conducted a number of trials on white rats and found that fragments of adrenocorticotropic hormones facilitate learning abilities.

It was not, however, until the late 1970s, when the Soviet Ministry of Defence commissioned a wide range of experiments to determine the optimal way to prolong the effects and increase their scope. After a long and complicated trial and error process, the optimal peptide formula was synthesized, and it had 50 times longer effects than its natural analogue. 

After that, an extensive research on humans was started to ensure safety, increase efficiency and determine the optimal dosages and delivery methods. As a result, on 20 December 1994, Semax® was officially brought to market. Since then it won a number of international awards and, on 7 December 2011, was included in the List of Vital & Essential Drugs, as studies showed that it was one of the most important remedies after strokes.

It is produced on a GMP-compliant factory by Peptogen Inc and is manufactured in two dosage forms: Semax® 0.1% and Semax® 1%:

Primary Uses of Semax® 0.1%:

• Increasing attention and memory during repetitive and monotonous tasks;
• Improvement of adaptive capacity of human body in extreme conditions and in extreme circumstances;
• Alleviating cognitive impairments caused by cerebrovascular disorders, traumatic brain injuries and neurosurgery;
• Cognitive disorders in kids above 7 y.o. including ADHD.

Primary Uses of Semax® 1%:

• Prevention and treatment of circulatory disorders including stroke;
• Acute ischemic stroke and treatment of cognitive inpairment caused by stroke;
• Transient ischemic attacks;
• Acute period of traumatic brain injury.

• In short, No. It is a pharmaceutical nootropic produced by Peptogen Inc. According to the official instruction (drug sheet), once opened a bottle of Semax® is to be kept at temperatures below 30°C (86°F) for a period of up to 30 days. Apart from that, we want to stress some other points:
• The product contains methylparaben (0.01%), which works as a preservative and ensures longer shelf-life. It is considered safe and is frequently used in other drugs.
• The product is sterile and is produced on a GMP-compliant factory, which is likely to increase storage duration.
• For longer periods of time, Semax should be stored at temperatures below 10°C (50°F). The shelf life of a new product is 2 years if stored below 10°C (50°F).

This implies that if the temperature between 10°C (50°F) to 30°C (86°F) the storage duration is anywhere between 30 days to 2 years, depending on the temperature.

*Up until now, nobody complained about Semax being unusable due to the heat during transportation, though we have been shipping for more than three years by now.

Dosage and Administration

One bottle of Semax contains 60 drops, each having 50 mcg of the active ingredient. The average dose is 2-3 drops in each nostril. Semax should be taken up to 3 times per day.

With the purpose of cognitive improvement, Semax should be taken 1-2 times a day - 2 drops in each nostril - for a period of 3 to 14 days. 

*Depending on the chosen regimen, one bottle is sufficient for a course of 3 - 10 days.

Side Effects

Irritation of the nasal mucosa and very rare allergic reactions.

Overdose

Semax was shown to be completely safe even when a hundredfold doses were administered.

Storage

Keep in a dark place at a temperature less than 10°C (50°F) for up to two years.

Note: If there is a need to increase the effect of Semax, a second dose 15-minutes after the first one should be taken. Using a stronger version might not result in a stronger effect, unless there is a strong indication.

Manufacture Contact Details: http://peptogen.ru, Moscow, Russia

Email: info@drugsafety.ru 

You can see the official website of Semax here

You can read the full instruction for 0.1% Semax here

You can read the full instruction for 1% Semax here

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SERMION® [Nicergoline]

$20.00

Nicergoline is an ergot derivative used primarily to treat senile dementia and other disorders which are known to have a vascular origin. It is known to decrease vascular resistance and increase arterial blood flow within the brain, thus improving the utilization of oxygen and glucose uptake by brain cells.

 Here you can read more.

 Availability: in stock

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STRESAM ® [Etifoxine]

$12.00

Stresam® (Also called Strezam) has anxiolytic properties and can relieve various psychosomatic disorders, while not having negative effects on psychomotor and cognitive domains. The drug was shown to promote neurone growth; in particular, it accelerates axonal regeneration. Etifoxine is also used to alleviate mild depressions. 

Availability: in stock

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TABEX ® [Cytisine]

$18.00

Tabex ® is a innovative mean of quitting smoking, as its active component, Cytisine, interacts with the same receptors as Nicotine does. It alleviates abstinence syndroms (bad mood, irritability, headache, etc) and can tremendously increase the likelyhood of staying nicotine-free for the first days of abstinence.

Availability: in stock

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TENOTEN ®

$10.00

Tenoten ® is a homeopathic medicine that is said to have anxiolytic and nootropic effects; the manufacturer claims that it was shown to have a neuroprotective action in the experimental models of intoxication, hypoxy, and transient ischaemic attacks. 

The mechanisms of these effects might be attributed to the antibodies against S-100 protein: at ultra-low doses, they exert GABA-mimetic and neurotrophic actions, up-regulate stress-limiting systems and contribute to the restoration of neuroplasticity.

However, the amount of the active ingredient in the drug appears to be too small to have all these effects. 

Availability: in stock

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VINPOTROPILE ® [Vinpocetine & Piracetam]

$10.00 $15.00

Vinpotropile ® is a combination of Vinpocetine and Piracetam. It was found that Vinpocetine has cerebral-flow enhancing and neuroprotective effects. Vinpocetine and Piracetam work synergistically, with Vinpocetine improving mainly blood flow and Piracetam increasing glucose and oxygen consumption.

Availability: in stock

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VISOMITIN (Skulachev Ions | SKQ1 eye drops)

$22.00

The main aspect of the mechanism of action of SkQ1 is protecting mitochondria from oxidative stress, which is a confirmed key factor in cell aging. That’s one of the reasons SkQ1 proved to be effective in a wide spectrum of models of age-related disorders. The main target of SkQ1 is to extend a healthspan.

The mechanism of action of SkQ1 involves at least two extremely complex and novel concepts: delivering a an extremely active antioxidant plastoquinone inside mitochondria and reducing reactive oxygen species production inside mitochondria in a controlled and sustainable manner.

Availability: in stock

Try also other SkQ1 revolutionary products: Exomitin^(®), MitoVitan^(®),MitoVitan Active^(®).

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