AFOBAZOLE [Fabomotizole]

$10.00

60 pills x 10mg / Russia Sample: 30 pills x 10mg - 9 USD / Russia 60 pills x 10mg / US (+15%)

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AFOBAZOLE stabilises and upregulates GABA and benzodiazepine receptors, exhibits neuroprotective properties, and diminishes anxiety and tensions in the body. The drug is designed above all for people with asthenic personal traits such as emotional lability, e.g. tendency to react emotionally in stressful situations.  

Availability: in stock

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Aralia Tincture

$6.00

50 ml / Russia

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Aralia is a well-known gentle adaptogenic tonic herb popular for its wide range of pharmacological properties. It is used to treat physical and mental fatigue, asthenic syndrome, arterial hypotension, decreased sex drive, mental breakdown, depression, enuresis, radiation sickness and metabolic disorders. This herbal remedy can also help to recover from craniocerebral injury, contusion, meningitis, post-infectious arachnoiditis and ARVI (in the complex therapy). 

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BEMITIL [Metaprot]

$10.00

Sample: 10 pills x 250mg / Russia Sample: 5 pills x 250mg / Russia 10 pills x 250mg / US (+15%) Box: 40 pills x 250mg / Russia Box: 40 pills x 250mg / US (+15%)

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Developed in the Soviet Union for the needs of the military, Bemitil (also known as Metaprot and AntiHot) has a long history of usage in clinical practice and in sport. It was developed in the 1970s and was successfully used during Afghanistan war, Chernobyl catastrophe and Olympic games in Moscow.

The drug has nootropic, regenerative, antihypoxic, antioxidant and immunomodulatory action.

A perfect alternative for the discontinued Ladasten (Bromantane)

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CEREBROLYSIN®

$42.00

5 ampoules x 5ml / Russia 10 ampoules x 2ml / Russia 5 ampoules x 10ml / Russia 5 ampoules x 5ml / US (+15%) 5 ampoules x 10ml / US (+15%)

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Cerebrolysin ® is a neurometabolic stimulator based on neuropeptides (20%) and amino acids (80%) isolated from pig brain proteins. Unlike the majority of peptide drugs, Cerebrolysin ® has all the amino acids which compose the central nervous system; this can explain many additional positive properties of Cerebrolysin ®.  

IT CAN BE KEPT OUTSIDE OF REFRIGERATOR WITH TEMPERATURE BELOW 25 ℃ (77.00 ℉)

Fast Domestic shipping available! 🇺🇸

Availability: in stock

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CERETON ® [Alpha-GPC]

$18.00

28 pills x 400mg / Russia 14 pills x 400mg / Russia 3 ampoules x 4ml (1000 Mg each ampoule) / Russia 5 ampoules x 4ml (1000 Mg each ampoule) / Russia 28 pills x 400mg / US (+15%)

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Cereton® is the most efficient cholinergic supplement in terms of increasing brain concentration of choline. In the brain, choline and its metabolites are needed for the cholinergic neurotransmission - the process of communication between neurons. Increasing phosphatidylcholine and acetylcholine as a result of taking Alpha-GPC might improve certain cognitive functions, including memory retention, focus, and neuroplasticity.

Availability: in stock

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CYTAMINS [NATURAL PEPTIDES]

$20.00

Cerebramin (brain) / Russia Vasalamin (blood vessels) / Russia Ventramin (stomach) / Russia Pankramin (pancreas glands) / Russia Ovariamin (ovaries) / Russia Testalamin (gonads) / Russia Hondramin (cartilaginous tissue) / Russia Koramin (cardio-vascular system) / Russia Epiphamine (hypophysis) / Russia Renisamin (kidneys) / Russia Tiramin (thyroid) / Russia Bronholamin (bronchi) / Russia Timusamin (timus) / Russia Hepatamin (liver) / Russia Respiratory system (Bronhalamin, Timusamin, Vasalamin) / Russia Urinary system (Renisamin, Vasalamin, Timusamin) / Russia Mens health (Prostalamin, Testalamin, Vasalamin) / Russia Immune system (Timusamin, Epifamin, Vasalamin) / Russia Brain system (Cerebramin, Vasalamin, Renisamin) / Russia Musculoskeletal system (Hondramin, Vasalamin, Hepatamin) / Russia Digestive system (Ventramin, Hepatamin, Pankramin) / Russia Cardiovascular system (Koramin, Vasalamin, Renisamin) / Russia

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CYTAMINS are proteins, nucleoproteins and minerals isolated from organs of pigs and calves less than 12 months old. These peptide regulators are completely safe supplements that have been used for anti-ageing purposes and also as an aid to conventional treatment methods.

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CYTOGENS [SYNTHESIZED PEPTIDES]

$35.00

Pinealon (brain) 60 pills / Russia Vesugen (blood vessels) 60 pills / Russia Cartalax (joints and bones) 60 pills / Russia Crystagen (immune system) 60 pills / Russia Ovagen (liver) 60 pills / Russia Honluten (respiratory system and stomach) 60 pills / Russia Pancragen (pancreas) 60 capsules / Russia Bronchogen (bronchi) 60 capsules / Russia Vesilut (urinary system) 60 capsules / Russia Testagen (reproductive system) 60 capsules / Russia Cardiogen (cardiovascular system) 60 capsules / Russia Normoftal (visual system) 60 capsules / Russia

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CYTOGENS (SYNTHESIZED PEPTIDES) are physiologically active short peptides; they are synthesized combinations of 2-3 amino acids. Cytogens have a faster action compared to extract peptides - CYTOMAX peptides. By reducing peptide deficiency within organs and restoring protein synthesis, Cytogens regulate work and functionality of organs and slow down the ageing process. These peptides can be easily combined with other supplements and medicines and should be used in addition to conventional medical treatment.

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CYTOMAXES [NATURAL PEPTIDES]

$35.00 $49.00

Cerluten (nervous system) 60 pills / Russia Endoluten (neuroendocrine system) 20 pills / Russia Ventfort (blood vessels) 60 pills / Russia Gotratix (muscles) 60 pills / Russia Visoluten (eyes) 60 pills / Russia Suprefort (pancreas) 60 pills / Russia Chelohart (heart) 60 pills / Russia Pielotax (kidneys) 60 pills / Russia Sigumir (joints and bones) 60 pills / Russia Stamokort (stomach) 60 pills / Russia Svetinorm (liver) 60 pills / Russia Testoluten (testicles) 60 pills / Russia Libidon (prostate) 60 pills / Russia Bonomarlot (bone marrow) 60 pills / Russia Bonothyrk (Parathyroid) 60 pills / Russia Glandokort (adrenals) 60 pills / Russia Taxorest (bronchi) 60 pills / Russia Vlandonix (immune system) 60 pills / Russia Thyreogen (Thyroid) 60 capsules / Russia Zhenoluten (women's reproductive system) 60 capsules / Russia Cerluten (nervous system) 20 pills / Russia

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CYTOMAXES [NATURAL PEPTIDES] is a group of peptides of less than 50 amino acids and with a molecular mass of less than 5 kDa, free from foreign DNA or protein substance, extracted from organs and tissues of young calves by a patented method of thorough filtering. 5 kDa is very little. The molecular mass of DNA fragments and proteinaceous infectious particles, the prions, are several times bigger than that. Therefore these peptide supplements are extremely clean products. They do not have any immunogenic or mutagenic properties.

Peptide bioregulators are shorter than proteins and can be absorbed via the digestive system. They have been shown to shortcut the protein synthesis process by interacting directly with cell DNA - meaning that organs can build and repair tissues easier and quicker when peptide bioregulators are active.

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Eleuthero liquid extract (Siberian ginseng)

$6.00

50 ml / Russia

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Eleuthero (also known as Siberian Ginseng) has been part of the herbal repertoire in traditional medicine for thousands of years and continues to gain increasing popularity nowadays. It is a very powerful adaptogen that can help not only to increase stamina but also to promote overall health. The short list of indications for use includes: physical and mental fatigue, arterial hypotension, neurasthenia, asthenia, nervous breakdown and protracted recovery from somatic and infectious diseases.

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ENERION ® [Sulbutiamine]

$11.00

20 pills x 200mg / Russia 60 pills x 200mg / Russia Sample: 10 pills x 200mg / Russia 20 pills x 200mg / US (+15%)

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ENERION ® is a modified thiamine (vitamin B1), that can easily cross the blood-brain barrier. In the brain, it produces both GABA and acetylcholine, thus affecting adaptability, mood and focus.

Availability: in stock

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ENTROP (PHENOTROPIL) [Phenylpiracetam]

$44.00

Entrop: 20 pills x 100 mg / Russia Entrop: 20 pills x 100 mg / US (+15%) Sample: Entrop: 10 pills x 100 mg / Russia

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Phenotropil ® is a phenyl - derivative of Piracetam. It is reported to be more neuroprotective than the original compound; it was also shown to possess psychostimulatory and various adaptogenic properties.

Entrop ® is a pharmaceutical product with the same active ingredient, phenylpiracetam and it is produced by a Latvian company, Olainfarm.

Availability: Very limited availability

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EXOMITIN (Skulachev Ions | SKQ1 regenerating antioxidant hydrogel)

$27.00

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Exomitin is designed for skin damages and problems, including burns and scars. Due to its innovative formula, the mitochondrial antioxidant SkQ1 protects and soothes the skin in case of different types of irritation, redness and dryness. In equal measure Exomitin improves the skin health, restores its regenerative functions, accelerates tissue repair; it also increases antioxidant defense of skin cells. The use of hydrogel provides proper skin care and improves skin resistance to adverse environmental factors.

The mitochondrial antioxidant SkQ1 (“Skulachev's Quinone”) is based on plastoquinone (a substance extracted from the most oxygenated place in the wild - chloroplast of the plants). It is clinically proven that SkQ1 reduces the free radicals activity in the mitochondria at the cellular level and therefore interrupts the aging program. After all, it is toxic forms of oxygen produced by mitochondria that trigger the process of programmed skin cells death (keratinocytes and fibroblasts apoptosis).

Due to its unique properties, the effectiveness of the SkQ1 antioxidant is 1000 times greater than that of the other well-known antioxidants, including famous coenzyme Q10. You can notice a pronounced effect already after the first application of the hydrogel.  Exomitin is suitable for a long-term use and can be mixed with other skin care products.

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Ginseng Tincture (Panax ginseng)

$5.90

25 ml / Russia

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Ginseng or Panax is one of the most popular and widely-researched herbal remedies in the world. It is even believed to be a natural cure-all and can be used for a wide variety of purposes, such as low mood and decreased mental capacity. The short list of indications for its use includes: physical and mental fatigue, arterial hypotension, asthenic syndrome, nervous breakdown, sexual dysfunction, neurocirculatory dystonia (hypotonic type) and protracted recovery period after a number of diseases (incl. infections). 

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Leuzea-P (Rhaponticum carthamoides or Maral root)

$8.00

Size Leuzea-P 100 pills

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Leuzea (Rhaponticum) has been used in traditional Siberian medicine to bolster both physical and mental performance (especially after illness). The major requirement associated with Leuzea is the enhancement of physical strength and muscle protein synthesis. The other indications for use include mental and physical fatigue, asthenia, exhaustion, decreased mental and physical capacity, irritability, headache, chronic alcoholism, erectile dysfunction.

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MEMANTALE [Memantine]

$9.00 $75.00

30 pills x 10mg / Russia 60 pills x 10mg / Russia 90 pills x 10mg / Russia Sample: 10 pills x 10 mg / Russia

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Synthesised by Eli Lilly and Company in 1968, Memantine is one of the few pharmaceuticals approved by the FDA for the treatment of moderate to severe Alzheimer's disease. Off-label use of Memantine also includes reversing tolerance for caffeine, nicotine and opioids; it may also be taken for a treatment of generalised anxiety disorder. 

Memantine reduces certain types of brain activity by binding to NMDA receptors and blocking the activity of glutamate. As a result, Memantine upregulates receptors in the brain and has a cognitive-enhancing effect.

Availability: in stock

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MEXIDOL ®

$7.00 $0.00

30 pills x 125mg / Russia 50 pills x 125mg / Russia 10 ampoules 5% x 2ml / Russia Sample: 10 pills x 125mg / Russia 50 pills x 125mg / US (+15%)

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 Mexidol^® is a unique development of the Russian pharmaceutical industry. Due to the universal mechanism of action and a wide range of pharmacological effects, Mexidol® is effective in the treatment of acute and chronic diseases caused by ischemia and hypoxia of various origins. Nowadays the drug is widely used in neurology, therapy, cardiology, psychiatry and narcology. Mexidol® is produced at leading pharmaceutical manufacturing sites in the Russian Federation, which operate in accordance with GMP (Good Manufacturing Practice) production and quality control standards. 

 The development of Mexidol® is closely associated with the name of the Soviet chemist N.N. Semenov, who was awarded the Nobel Prize in Chemistry for his piece of research on free radicals in 1956. Understanding the mechanisms of the free radical formation became the basis for creating the concept of combating tissue ischemia and for developing drugs with antioxidant and antihypoxic activity. The work on Mexidol® was continued by the students of N.N. Semenov in the 1980s. The drug has been in clinical practice since the middle 1990s.

 The presence of succinate in the structure of Mexidol^® is of fundamental importance for the manifestation of its pharmacological effects, since succinate is functionally significant for many processes in the body. In particular, it is a substrate for increasing the energy metabolism in the cell. Due to its properties, free radicals, which have a damaging effect on the cellular structures, are deactivated.

 Mexidol® is known to treat the followings diseases:

• Neurological problems: vegetovascular dystonia, acute cerebral circulation disorders, cognitive problems associated with cerebral arteriosclerosis (impaired memory, speech, loss of basic skills, etc.);
• In psychiatry: withdrawal syndrome (alcohol or drug withdrawal), anxiety, neurosis, intoxication with drugs from the group of antipsychotics;
• In surgery: for the complex treatment of acute purulent-inflammatory processes in the peritoneum.

Dosage and Administration 

The drug is taken orally, 1-2 pills 3 times a day, maximum daily dose is 6 pills. The general period of therapy is 2-6 weeks. The duration of the therapy for the alcohol abstinence treatment is 5-7 days. The duration of treatment in case of ischemic heart disease is 1.5 - 2 months or more.

Contraindications

Hypersensitivity, acute kidney and liver diseases. Pregnancy and lactation.

Side Effects & Overdose

Allergic reactions are possible. The patient may feel drowsiness in case of an overdose. Hence special caution must be taken when driving vehicles and engaging in other potentially dangerous activities.

Awards:

• 2003 - award of the Government of the Russian Federation for the development and implementation of Mexidol^® in clinical practice;
• 2014 - Russian Pharma Awards in the nomination “The Drug of Choice in the Treatment of Ischemic Disorders Caused by Cerebral Spasm”;
• 2016 - "Molecule of Life" award of the Russian Scientific Medical Community of Therapists.

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MILDRONATE ® [Meldonium]

$7.00

40 pills x 250mg / Russia 60 pills x 500mg / Russia Sample Mildronate: 10 pills x 250 mg / Russia Cardionate [Meldonium] 40 pills x 250mg, Russia / Russia 10 vials x 5ml / Russia 40 pills x 250mg / US (+15%) 60 pills x 500mg / US (+15%)

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Mildronate ® is used to treat angina, myocardial failure and reduce alcohol withdrawal symptoms. Off-label use of Meldonuim in otherwise healthy individuals includes increasing exercise tolerance, learning, memory, and sexual function.

Mildronate gained popularity after Maria Sharapova, a famous tennis player, said that she has been taking this drug for the last 10 years because of health reasons. Also, a number of other world and Olympic champions were tested positive for it. As of January 2016, this compound has been banned by WADA and may not be used by athletes anymore.

We recommend you this video explanation of Mildronate's effect in the cell.

Availability: in stock

A perfect alternative for the discontinued Ladasten (Bromantane)

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MitoVitan® (Skulachev Ions | SKQ1 anti-aging serum)

$95.00

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Read more in our blog post

MitoVitan is a completely new approach in interrupting the biological mechanism of aging. It disables the aging program at the cellular level and helps to maintain the youthfulness of the skin. Daily use of the serum prevents the formation of deep and mimic wrinkles, reduces the visibility of already existing ones and restores natural moisture balance and elasticity of the skin.

The active substance of MitoVitan is an innovative directional antioxidant SkQ1 (Skulachev's Quinone). In contrast to the common nondirectional antioxidants “Skulachev Ions” are sent directly to the mitochondria and reduce the free radicals activity at the cellular level, therefore interrupting the aging program. Due to its unique properties the effectiveness of the SkQ1 is 1000 times greater than that of the other well-known antioxidants, including famous coenzyme Q10.

The essential advantage of MitoVitan serum is its light structure, so that it is quickly absorbed and is invisible on the skin.

Package Content

The MitoVitan serum comes in a 30 ml flacon.

Main Uses

• Slows down the aging process;
• Improves the overall skin condition;
• Restores the skin's natural water balance and elasticity;
• Smoothes wrinkles and prevents the formation of new ones.

Contraindications

• Individual intolerance to the ingredients.

 

Dosage and Administration

Gently apply the MitoVitan serum to the clean face and neck, massage until it is completely absorbed.

For dry or sensitive skin, it is recommended to use the MitoVitan serum in combination with a moisturizer.

Apply the MitoVitan serum 1-2 times a day (preferably in the morning and in the evening). It can be used as the main skin-care product or as the base for your preferred face cream.

Storage and Handling: Store the MitoVitan serum in a dry place at room temperature up to 25 ° C. Protect from direct sunlight. Keep out of the reach of children.

Shelf Life: 2 years. Do not use after the expiration date.

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MitoVitan® Active (Skulachev Ions | SKQ1 anti-aging concentrate)

$49.00

MitoVitan® Active Solo / Russia MitoVitan® Active Set / Russia MitoVitan® Active Solo / US (+15%)

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Read more in our blog post

MitoVitan Active or SKQ1 (Skulachev Ions) mitochondrial antioxidant concentrate.

MitoVitan Active (Skulachev ions, SkQ1 Anti-Aging concentrate) contains the SkQ1 antioxidant, which is the world's first registered antioxidant targeting mitochondria.

The mitochondria are the place where skin-damaging free radicals are formed. SkQ1 is able to enter and accumulate directly inside them, which makes it a thousand times more potent and effective than coenzyme Q10.

There it neutralizes the excess of free radicals and thus interrupts the aging process at the intracellular level.

The essential advantage of MitoVitan Active concentrate is a personal approach. Every person is unique, each of us has different skin type and therefore we need different skin care. Thus, just take your favourite cream, serum or any other remedy, add several drops of MitoVitan Active, and here you are: you get your own cosmetic line!  

Composition: Purified water; Glycerol; Plastoquinonildecyltriphenyl-phosphonium Bromide (SkQ1); Lactic acid.

MitoVitan Active in available in two formats:

• Solo (one 8 ml vial of the concentrate),
• Set (two 8 ml vials of the concentrate; Mito-jar and Mito-spoon for use with thick cosmetic means, and Mito- vial for creating compositions with liquid cosmetic products).

 Main Uses

• Slows down the aging process;
• Improves the overall skin condition;
• Restores the skin elasticity;
• Smoothes wrinkles.

Contraindications

• Individual intolerance to the ingredients.

Dosage and Administration

The MitoVitan Active concentrate has to be used in combination with other cosmetics.

The concentrate can be used continuously or in a course. The recommended course of treatment lasts for three months.

Recipe No. 1 for cosmetics with a thick consistency

As a base, use any of your primary face and body skin-care products (including products for the area around the eyes).

Mix one or two drops of MitoVitan Active with one milliliter (measured with the mixing spoon) of your cosmetic product (cream, gel, tonic, milk, etc.). Stir the mixture thoroughly in the mixing jar until you get a uniform consistency.

Apply the resulting mixture lightly tapping your fingers along the massage lines of your cleansed face and neck to relax the muscles and normalize the blood circulation.

For convenience, the mixture can be prepared in a larger volume, but based on the same ratio - 1-2 drops of MitoVitan Active per one mixing spoon.

IMPORTANT: It is recommended to store the mixture for no more than two weeks.

Recipe No. 2 for liquid cosmetics

As a base, use any of your preferred products for the face, body and hair care.

Mix 10 ml (1/2 volume of the mixing bottle) of your cosmetic product with 10 drops of MitoVitan Active. Shake the sealed mixing bottle thoroughly for 20 seconds until a uniform consistency is achieved.

Apply the resulting mixture as told in the recommendations for the use of your base product.

IMPORTANT: It is recommended to store the mixture for no more than two weeks (except for the mixtures with cosmetic oils).

Note

MitoVitan Active is water-based, so it may be difficult to mix it with a cosmetic oil. In this case, it is recommended to shake the mixture vigorously right before applying it to the skin.

As a result, small bubbles of the concentrate will appear in the cosmetic oil, which should be applied to the skin as quickly as possible. Storage of the resulting mixture is not recommended.

Вo not combinine the concentrate with alkaline cosmetics (with pH value is above 7) - for example, with shampoos or liquid soaps. In this case, we recommend adding MitoVitan Active to hair balm or shampoos and soaps marked with a neutral pH or pH below 7.

Shelf life: 24 months. After the vial is opened, store at most 2 months at a temperature of 15-25 ° C in the dark place. Do not use beyond the expiration date printed on the package.

Country of Origin: Russia

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NOOPEPT ®

$9.00

50 pills x 10mg / Russia Sample: 25 pills x 10 mg / Russia 50 pills x 10mg / US (+15%)

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Recent decades have been marked by the ever-increasing use of drugs of nootropic action. This is due to the rhythm of modern life, which requires processing big amount of data, which creates a significant burden on the brain. In order to protect the brain from many adverse factors, drugs called nootropics have been developed. The term "nootropic drugs" is derived from the Greek noos (thinking, reason) and tropos (aspiration). This term was proposed in 1972 by S. Giurgea, who identified nootropics as a new group of drugs that have a specific activating effect on the integrative functions of the brain. The mechanism of the nootropic effect is multivalent. The nootropic concept has become the largest contribution to the development of psychopharmacology. Noopept® has a special place among a wide range of nootropic drugs. It is the result of a more than 20-year work of researchers from the Zakusov Scientific Research Institute of Pharmacology named after Vasiliy Zakusov an honoured pharmacologist of the Soviet Union.

Noopept® was created based on the peptide design methodology. It is an N-phenyl-acetyl-L-prolylglycine ethyl ester.  Its effect is physiological to the human body, as it is based on the formation of an active compound cyclopropyl glycine, which is naturally occurring in the brain. This substance is also called the "memory peptide." The drug has pronounced nootropic and neuroprotective properties in doses several times lower than those of Piracetam, but it is characterized by a much more diverse pharmacodynamics.

The drug contributes to:

• Reduction of headaches, dizziness, palpitations;
• Normalization of sleep;
• Decreasing the irritability and improving the emotional background;
• Improving health and reducing fatigue.

It will be useful both for young people who want to restore high concentration of attention and good memory and for people over 50 y.o. who need to maintain mental performance in the family, at work and in society. The drug can also help cope with the effects of a traumatic brain injury and a stroke, asthenic disorders and autonomic disorders.

https://www.youtube.com/watch?v=n_OaoO6noqc - official video-description of the drug.

https://www.youtube.com/watch?v=9qgh7WB0T9A - an interview with R. Ostrovskaya one of the scientists who created Noopept®.

 

Noopept® is an innovative nootropic developed by Russian scientists, which has an impact on three stages of memory: initial processing, storage and extraction (reproduction).  It helps the brain better adapt to damaging influences and other adverse factors that impair memory, attention and learning ability.

Dosage and Administration 

The use of Noopept® is simple and convenient: one tablet (10 mg) x 2 times a day (morning and afternoon). It is important to note that in order to achieve a full effect, the drug should be taken in a course (at least 1.5 months = 2 packs). The end of the course of treatment does NOT require a gradual reduction in dosage.

One pack of Noopept® contains 50 pills, each with 10 mg of the active substance, which is sufficient for approximately 20 days of administration.

Side effects: 

Allergic reactions are possible. However Noopept ® is generally well tolerated. Rare cases of side effects may include rise in blood pressure in patients with hypertension, which can be stabilized by standard antihypertensive drugs.

Overdose 

Specific manifestations of overdose have not been established. Noopept® has low toxicity, which justifies the possibility of the long-term use. 

Note:

The interaction of Noopept® with alcohol, hypnotics, hypotensive and psychostimulant drugs has not been established.

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NOOTROPIL ® [Piracetam, Lucetam]

$6.00 $8.00

NOOTROPIL ® 20 pills x 1200mg / Russia LUCETAM ® 30 pills x 800mg / Russia LUCETAM ® 30 pills x 800mg / US (+15%) NOOTROPIL ® 20%, 5 Ml, 12 Ampoules / Russia NOOTROPIL® - Oral Solution - 125 Ml, 200Mg/Ml (25gr) / Russia

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 It has been more than 40 years since Cornelia E. Giurgea - a Romanian chemist - synthesised a compound which was "capable of selectively influencing integrative mechanisms of the brain”. This chemical compound was Piracetam, which later appeared on the market under the brand name Nootropil ®, simultaneously giving birth to a whole range of pharmaceuticals which we now call nootropics.

Availability: in stock

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PANTOGAM ACTIVE ® [D,L-hopantenic acid]

$9.00

60 pills x 300mg / Russia PANTOGAM: 50 pills x 250mg / Russia Sample PANTOGAM ACTIVE: 15 pills x 300mg / Russia 60 pills x 300mg / US (+15%)

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The main substance of Pantogam Active® is a hopantenic acid developed in Japan in 1950. The hopantenic acid combines GABA and vitamin B5 that allows GABA to reach neurons of the central nervous system.

Pantogam Active® is a racemic mix of equal quantities of hopantenic acid and its S-isomer. An isomer presence improves a transport and interaction of the drug with GABA receptor.  GABA is the chief inhibitory neurotransmitter in the mammalian central nervous system. It plays the principal role in reducing neuronal excitability throughout the nervous system. Pantogam Active stabilizes neurotransmitters, i.e. makes them more resistant to temporary or permanent negative effects. 

Availability: in stock

Read the full instruction here 

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PHENIBUT ®

$9.00 $15.00

Phenibut: 20 pills x 250mg (Russia) / Russia Noophen: 20 pills x 250mg (Latvia) / Russia Phenibut: 20 pills x 250mg (Latvia) / Russia Phenibut: 20 pills x 250mg (Russia) / US (+15%) Phenibut: 20 pills x 250mg (Latvia) / US (+15%)

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Phenibut ® is a derivative of the naturally occurring inhibitory neurotransmitter GABA, which can cross the blood-brain barrier much better than the original compound. Unlike usual tranqualizers, Phenibut ® has both psychostimulating and anxiety reducing effects.

Availability: limited availability

The product is available from different manufactures.

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PICAMILON ® [Nicotinoyl-GABA]

$8.00

30 pills x 50mg / Russia

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Picamilon ® is based on a synthetic combination of GABA and niacin, with the former being responsible for reducing neuronal excitability and the latter acting as a strong vasodilator.

Its effects are similar to those of Phenibut, as both drugs reduce anxiety and improve mood. However, unlike Phenibut, Picamilon ® has a much stronger impact on energy metabolism in the brain because it stimulates consumption of oxygen and glucose by neuronal tissue.

Availability: in stock

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PRAMISTAR ® [Pramiracetam]

$27.00

20 pills x 600 mg / Russia Sample Pramistar: 10 pills x 600 mg / Russia 20 pills x 600 mg / US (+15%)

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Chemically very similar to Choline, Pramiracetam causes the formation of nitric oxide, a powerful vasodilator, which is crucial for short-term memory. It also affects neuropeptide mediation; as a result, it improves memory and learning processes.

Limited Availability

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Rhodiola Rosea extract (Golden Root)

$9.00

30 ml tincture / Russia

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Rhodiola Rosea has been used in traditional medicine for over a thousand years. The "Golden Root" is likely to be one of the most popular herbal adaptogens, second only to Panax Ginseng. It enhances physical work capacity, increases resistance to stress and improves memory without disturbing normal biological functions. Other potential indications for use of Rhodiola include asthenia, increased fatigability, protracted recovery from somatic and infectious diseases, mental and physical exhaustion, neurasthenia and arterial hypotension.

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Schisandra Chinensis Seeds Tincture

$5.90

25 ml / Russia

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Known since ancient times for its unique adaptogenic qualities, Schisandra Chinensis can treat various diseases and restore health after severe illnesses. The benefits of this herb have been proved in numerous studies showing that it is one the strongest natural antioxidants in the world. Schisandra will rejuvenate the body, increase the vital energy, enhance physical work capacity and strengthen stress resistance. Some indications for use include asthenic syndrome, chronic fatigue, in combination therapy for treating sexual dysfunction caused by neurasthenia, mental and physical exhaustion, neurocirculatory dystonia (hypotonic type) and protracted recovery from somatic and infectious diseases. 

 

1. A Panossian (2008) Pharmacology of Schisandra chinensis Bail.: An overview of Russian research and uses in medicine https://www.researchgate.net/publication/5336030_Pharmacology_of_Schisandra_chinensis_Bail_An_overview_of_Russian_research_and_uses_in_medicine
2. A Panossian, G Wikman (2010) Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress—Protective Activity https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991026/
3. Wang et al (2014) Supplementation with the Extract of Schisandrae Fructus Pulp, Seed, or Their Combination Influences the Metabolism of Lipids and Glucose in Mice Fed with Normal and Hypercholesterolemic Diet https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021675/
4. Li et al (2017) Compound Schisandra-Ginseng-Notoginseng-Lycium Extract Ameliorates Scopolamine-Induced Learning and Memory Disorders in Mice https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549506/
5. Szopa et al (2017) Current knowledge of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine) as a medicinal plant species: a review on the bioactive components, pharmacological properties, analytical and biotechnological studies https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378736/
6. Szopa et al (2018) Phytochemical and biotechnological studies on Schisandra chinensis cultivar Sadova No. 1—a high utility medicinal plant https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959991/
7. Lee et al (2018) Deoxyschizandrin, Isolated from Schisandra Berries, Induces Cell Cycle Arrest in Ovarian Cancer Cells and Inhibits the Protumoural Activation of Tumour-Associated Macrophages https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793319/
8. Nowak et al (2019) Potential of Schisandra chinensis (Turcz.) Baill. in Human Health and Nutrition: A Review of Current Knowledge and Therapeutic Perspectives https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412213/

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SELANK ® 0.15%

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Selank® 0.15% is an anxiolytic peptide drug with nootropic properties. By its structure, Selank is based on endogenous tetrapeptide Tuftsin, which plays an important role in immune system. To slow the breakdown of peptide and prolong its effects, the inventors of Selank added a Glyproline to its structure.

Tafcin was found to have anxiolytic effects in 1995 and over the next decade Russian scientists were focusing on developing a peptide drug that was able to have the most pronounced anxiolytic effects. This research, as well as clinical trials lasted until 2009, when Selank was finally brought to market under the brand name Selank® 0.15%. It is produced on a GMP-compliant factory by Peptogen Inc. 

The spectrum of pharmacological action of the drug is unique. It is a popular over-the-counter anti-anxiety medicine with antidepressant and anti-asthenic actions; it also has a capacity to enhance memory and cognitive functions. 

The mechanism of anxiolytic action is related to the regulation of norepinephrine, serotonin and enkephalins levels and their metabolism in the brain. It is suggested that another possible mechanism of action is inhibition of enkephalin-degrading enzymes, which increases the activity of endogenous opioid system and explains the mild analgesic effect of Selank.

Numerous clinical trials confirmed the safety of this peptide, which was found to not form a dependence and to be non-toxic even in doses 200-500 times higher than therapeutic ones.

Primary Uses of Selank® 0.15%:

• Anxiety and adjustment disorders;
• Neurasthenia, emotional lability;
• Stress-related disorders.

Is Selank going to be degraded after a long journey from Russia to the US?

• In short, No. It is a pharmaceutical nootropic produced by Peptogen Inc. According to the official instruction (drug sheet), once opened a bottle of Selank® is to be kept at temperatures below 30°C (86°F) for a period of up to 30 days. Apart from that, we want to stress some other points:
• The product contains methylparaben (0.01%), which works as a preservative and ensures longer shelf-life. It is considered safe and is frequently used in other drugs.
• The product is sterile and is produced on a GMP-compliant factory, which is likely to increase storage duration.
• For longer periods of time, Selank should be stored at temperatures below 10°C (50°F). The shelf life of a new product is 2 years if stored below 10°C (50°F).

This implies that if the temperature between 10°C (50°F) to 30°C (86°F) the storage duration is anywhere between 30 days to 2 years, depending on the temperature.

 

*Up until now, nobody complained about Selank being unusable due to the heat during transportation, though we have been shipping for more than three years by now.

 

Dosage and Administration

One bottle of Selank contains 60 drops, each having 75 mcg of the active ingredient. The average dose is 2-3 drops in each nostril. Selank should be taken up to 3 times per day.

On-label regimen of Selank is 3 times a day, 2 drops in each nostril, for a period of 14 days. 

Side Effects

Irritation of the nasal mucosa and very rare allergic reactions.

Interaction With Other Drugs

Selank has no effect on depressants or stimulants including Haloperidol, Pentobarbital, Hexobarbital and analeptics. It can be combined with psychotherapy. It is safe to use with ethanol containing substances.

Overdose

Selank was shown to be completely safe even when hundredfold doses were administered.

Storage

Keep in a dark place at a temperature less than 10°C (50°F) for up to two years.

Note: If there is a need to increase the effect of Selank, a second dose should be taken 15-minutes after the first one. 

Manufacture Contact Details: http://peptogen.ru, Moscow, Russia

Email: info@drugsafety.ru 

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SEMAX®

$16.50

3ml/pack, 0.1% / Russia 3ml/pack, 1% / Russia

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Semax® is a Russian nootropic drug that is used as nasal drops to improve cognitive functions and treat various medical conditions. By its structure, Semax® is a fragment of endogenous neuropeptide ACTH. The drug was shown to increase BDNF that is responsible for the growth and differentiation of new neurons and synapses.

The positive effects of neuropeptides were discovered in the late 1960s when D. de Vid - who coined the term neuropeptide - conducted a number of trials on white rats and found that fragments of adrenocorticotropic hormones facilitate learning abilities.

It was not, however, until the late 1970s, when the Soviet Ministry of Defence commissioned a wide range of experiments to determine the optimal way to prolong the effects and increase their scope. After a long and complicated trial and error process, the optimal peptide formula was synthesized, and it had 50 times longer effects than its natural analogue. 

After that, an extensive research on humans was started to ensure safety, increase efficiency and determine the optimal dosages and delivery methods. As a result, on 20 December 1994, Semax® was officially brought to market. Since then it won a number of international awards and, on 7 December 2011, was included in the List of Vital & Essential Drugs, as studies showed that it was one of the most important remedies after strokes.

It is produced on a GMP-compliant factory by Peptogen Inc and is manufactured in two dosage forms: Semax® 0.1% and Semax® 1%:

Primary Uses of Semax® 0.1%:

• Increasing attention and memory during repetitive and monotonous tasks;
• Improvement of adaptive capacity of human body in extreme conditions and in extreme circumstances;
• Alleviating cognitive impairments caused by cerebrovascular disorders, traumatic brain injuries and neurosurgery;
• Cognitive disorders in kids above 7 y.o. including ADHD.

Primary Uses of Semax® 1%:

• Prevention and treatment of circulatory disorders including stroke;
• Acute ischemic stroke and treatment of cognitive inpairment caused by stroke;
• Transient ischemic attacks;
• Acute period of traumatic brain injury.

Is Semax® going to be degraded after a long journey from Russia to the US?

• In short, No. It is a pharmaceutical nootropic produced by Peptogen Inc. According to the official instruction (drug sheet), once opened a bottle of Semax® is to be kept at temperatures below 30°C (86°F) for a period of up to 30 days. Apart from that, we want to stress some other points:
• The product contains methylparaben (0.01%), which works as a preservative and ensures longer shelf-life. It is considered safe and is frequently used in other drugs.
• The product is sterile and is produced on a GMP-compliant factory, which is likely to increase storage duration.
• For longer periods of time, Semax should be stored at temperatures below 10°C (50°F). The shelf life of a new product is 2 years if stored below 10°C (50°F).

This implies that if the temperature between 10°C (50°F) to 30°C (86°F) the storage duration is anywhere between 30 days to 2 years, depending on the temperature.

 

*Up until now, nobody complained about Semax being unusable due to the heat during transportation, though we have been shipping for more than three years by now.

 

Dosage and Administration

One bottle of Semax contains 60 drops, each having 50 mcg of the active ingredient. The average dose is 2-3 drops in each nostril. Semax should be taken up to 3 times per day.

With the purpose of cognitive improvement, Semax should be taken 1-2 times a day - 2 drops in each nostril - for a period of 3 to 14 days. 

*Depending on the chosen regimen, one bottle is sufficient for a course of 3 - 10 days.

Side Effects

Irritation of the nasal mucosa and very rare allergic reactions.

Overdose

Semax was shown to be completely safe even when a hundredfold doses were administered.

Storage

Keep in a dark place at a temperature less than 10°C (50°F) for up to two years.

Note: If there is a need to increase the effect of Semax, a second dose 15-minutes after the first one should be taken. Using a stronger version might not result in a stronger effect, unless there is a strong indication.

Manufacture Contact Details: http://peptogen.ru, Moscow, Russia

Email: info@drugsafety.ru 

You can see the official website of Semax here

You can read the full instruction for 0.1% Semax here

You can read the full instruction for 1% Semax here

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SERMION® [Nicergoline]

$20.00

30 pills x 5mg / Russia 50 pills x 10mg / Russia 30 pills x 30mg / Russia Nicergoline (generic) 30 pills x 10mg / Russia

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Nicergoline is an ergot derivative used primarily to treat senile dementia and other disorders which are known to have a vascular origin. It is known to decrease vascular resistance and increase arterial blood flow within the brain, thus improving the utilization of oxygen and glucose uptake by brain cells.

 Here you can read more.

 Availability: in stock

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STRESAM ® [Etifoxine]

$13.00

24 pills x 50mg / Russia 60 pills x 50mg / Russia Sample: 20 pills x 50mg / Russia 60 pills x 50mg / US (+15%) 24 pills x 50mg / US (+15%)

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Stresam® is a drug manufactured by the French company Biocodex. Its active substance - etifoxine, a benzoxazine derivative - has an original mechanism of action that distinguishes it from all other anxiolytics. It is characterized by maximum selectivity and physiological action in relation to the influence on the development of the symptom complex of anxiety.

Active substance was developed back in the 1960s by the German pharmaceutical company, when benzodiazepines (psychoactive substances with sedative effects), dominated the market of sedatives and drugs for anxiety disorders. However, despite their popularity, tranquilizers of the benzodiazepine structure have significant side effects: psychomotor inhibition, drowsiness, lethargy, dizziness, muscle relaxation, memory impairment, development of addiction, etc. An alternative way to develop drugs to eliminate anxiety was the synthesis and implementation of new generation anxiolytics of non-benzodiazepine nature. Etifoxine was one of several anxiolytics with enough potential to replace benzodiazepine drugs.

It has anxiolytic properties and can relieve various psychosomatic disorders (anxiety, internal tension, sleep disturbances, irritability, inadequate emotional reactions), without a negative effect on psychomotor and cognitive domains. The compound produces neurosteroids in the brain that can indirectly modulate the activity of GABAA response. Enhancing neurosteroids in the brain has a lot of potential in keeping the functional yet calm state of body and mind. Stresam® which is an official trade name of etifoxine demonstrates the following effects:  

• The drug effectively eliminates manifestations of anxiety (stress, discomfort, insomnia, a sense of fear, etc.).
• Since the active substance of Stresam® does not have a withdrawal syndrome and does not cause dependence, etifoxine is of great interest for narcologists: the drug has shown its effectiveness in reducing manifestation of alcohol withdrawal syndrome, reducing tremor, anxiety and paroxysmal sweating. Stresam® helps to reduce the pathological craving for alcohol, improving the quality of life in the post-withdrawal period. 
• Additional effects of Stresam® are due to the fact that the drug has a mediated effect at the intracellular level: it stimulates mitochondrial benzodiazepine receptors, thereby enhancing the synthesis of neurosteroids. According to preliminary data, these effects stipulate an improvement in concentration and memory functions, which increases the ability to learn.
• Another property of Stresam® that has been recently discovered is neuroprotection. Stresam® was shown to promote neuron growth; in particular, it accelerates axonal regeneration and might serve as a treatment for polyneuropathy.
• Stresam® was also proven to have the ability to alleviate mild depressions which are widespread nowadays.
• Stresam® has an indirect effect on the course of cardiovascular, pulmonary, gastroenterological and other diseases of psychosomatic nature.

The facts mentioned above make this drug a decent alternative to other anxiolytics currently used in everyday medical practice in the treatment of anxiety disorders of various origins. The drug is approved in more than 40 countries.

In general, it can be argued that the etifoxine anxiolytic Stresam® is effective in treating a very wide range of anxiety-neurotic disorders and psychosomatic pathologies, sleep disorders, vegetative-vascular dystonia, etc. The drug does not adversely affect psychomotor and cognitive functions and muscle tone; it does not cause dependence, tolerance and does not have a withdrawal syndrome.

Dosage and Administration 

Very few side effects in Stresam® administration provide possibilities for dose variations in accordance with the therapeutic necessity (taken existings recommendations, patients' peculiarities and the specifics of symptoms). The usual dose is 1-2 capsules 2-3 times a day from 1 week to 2 months. For the full information on the administration, please refer to the official description.

Side effects 

Stresam® is devoid of a significant amount of side effects of its precursors (benzodiazepines). Rare side effects include dizziness, insomnia and the development of skin allergic reactions.

Contraindications

Liver / kidney disease is a contraindication as well as pregnancy / lactation and child age.

Overdose 

Overdose is noted only in doses many times higher than the recommended ones, and is limited to the effects of hypotension, eliminated by the appropriate treatment.

Analogs

Stresam® does not have structural analogues. Sedatives with a similar mechanism of action are:

• Xanax;
• Ativan;
• Valium; 
• Atarax, etc.

 

 

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TABEX ® [Cytisine]

$18.00

100 pills x 1.5mg / Russia 100 pills x 1.5mg / US (+15%) Sample: Tabex 50 pills x 1.5mg / Russia

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Tabex ® is a innovative mean of quitting smoking, as its active component, Cytisine, interacts with the same receptors as Nicotine does. It alleviates abstinence syndroms (bad mood, irritability, headache, etc) and can tremendously increase the likelyhood of staying nicotine-free for the first days of abstinence.

Availability: in stock

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TENOTEN ®

$12.00

40 pills x 3mg / Russia

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Tenoten ® is a homeopathic medicine that is said to have anxiolytic and nootropic effects; the manufacturer claims that it was shown to have a neuroprotective action in the experimental models of intoxication, hypoxy, and transient ischaemic attacks. 

The mechanisms of these effects might be attributed to the antibodies against S-100 protein: at ultra-low doses, they exert GABA-mimetic and neurotrophic actions, up-regulate stress-limiting systems and contribute to the restoration of neuroplasticity.

However, the amount of the active ingredient in the drug appears to be too small to have all these effects. 

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VINPOTROPILE ® [Vinpocetine & Piracetam]

$25.00

Size 30 pills x 400mg Piracetam & 5mg Vinpocetine - $15 60 pills x 800mg Piracetam & 10 mg Vinpocetine - $30 - save 50%

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Vinpotropile® is a combination drug. It is able to improve cerebral blood flow due to the active substance Vinpocetine and it can exert a nootropic effect through Piracetam, which is another active substance. This drug was developed in cooperation with N. Yakhno the Academician of the Russian Academy of Sciences. The optimal dosage of the components in Vinpotropile® and their proven synergy at the molecular level provide good tolerance and allow the drug to be used in a wide range of daily dosages.

Characteristics of the active components of the drug:

Vinpocetine was first isolated from Lesser Periwinkle plant by a Hungarian chemist Csaba Szántay. It was found that the compound had a cerebral-flow enhancing and neuroprotective effect. Over the last decades, it has been extensively studied and now is used in Eastern Europe for the treatment of cerebrovascular disorders and age-related memory impairment. 

Piracetam is a nootropic drug, historically the first and main representative of this group of drugs. It was first synthesized in the 1960s by Corneliu E. Giurgea. In Russia and Europe, Piracetam is widely used in clinical practice for the treatment of many neurological, psychiatric and other diseases.

Active components of Vinpotropile® have the following properties:

• Hemorheological Action (Reducing Blood Viscosity): Vinpocetine and Piracetam reduce the ability of platelets to aggregate, thus decreasing blood coagulation. They increase the ability of erythrocytes to deform and pass through the blood vessels.
• Blood Supply to the Brain: Vinpocetine improves blood supply to ischemic sections. Piracetam dilates the brain blood vessels.
• Brain Cell Metabolism: Vinpocetine binds to specific proteins, normalizing the membrane potential of cells, i.e. increasing ATP synthesis. Piracetam alters the properties of the mitochondrial membrane, contributing to better permeability of the active substances.
• Antioxidant action: Vinpocetine reduces the concentration of reactive oxygen species and blocks lipid peroxidation (formation of free radicals). Piracetam increases the resistance of the membranes to oxidative stress (exposure to free radicals).
  It activates antioxidant system enzymes.
• Neuroprotective Action: Vinpocetine and Piracetam prevent the pathological death of neurons (apoptosis). Piracetam also enhances the utilization of oxygen in the brain. It has a membrane stabilizing effect, and stimulates alternative mechanisms for maintaining energy metabolism.
• Improving Memory and Cognitive Function: Vinpocetine activates the locus coeruleus fibers (a group of neurons diffusely distributed throughout the cerebral cortex and involved in the regulation of cognitive brain functions). Piracetam acts on substances that potentiate neurogenesis, improving or restoring cognitive functions.

Due to the combination composition, Vinpotropile® has a complex pathogenetic effect on the development factors of vascular cognitive impairment. Vinpotropile® has a multifactorial effect and reduces the number of drugs taken. This significantly increases the effectiveness of the cognitive deficit therapy.

 

INTENDED USES

• Circulatory failure of the brain, dizziness, migraines;
• Parkinsonism of the vascular origin;
• Intoxication, alcoholism;
• Psycho-organic syndrome with signs of adynamia and asthenia, etc.

 

DOSAGE AND ADMINISTRATION 

The medicine is indicated for adult patients only, it is not recommended during pregnancy and lactation.

Currently, there are two forms of Vinpotropile® release: capsules (vinpocetine 5 mg and piracetam 400 mg) and tablets (vinpocetine 10 mg and piracetam 800 mg). Dosage: 1 - 2 capsules / tablets, 2 - 3 times per day. Course: 3 - 8 weeks. Before cancellation, the dose should be gradually reduced. For the full information on the administration, please refer to the official description.

SIDE EFFECTS & OVERDOSE 

The side effects include urticaria or dermatitis, gastralgia, heartburn and diarrhea. Other side effects often include tachycardia, extrasystole, angina pectoris, and hot flashes. Possible side effects in the central nervous system include headache, hyperkinesis, excitation, depression, increased sweating and extrapyramidal disorders.

Overdose can be manifested in the form of increased severity of side effects. For more information, please refer to the description.

NOTE:

It is strictly prohibited to use the drug along with alcohol-containing substances. It is possible to drink alcohol one day before or after using the drug for men, and two days before or after - for women. If the drug is used as a course treatment, a patient can start drinking alcohol after one month from the end of the full course.       

CLOSE ANALOGS:

• Cavinton ® [Vinpocetine]
• Noben ® [Idebenon]

 

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VISOMITIN (Skulachev Ions | SKQ1 eye drops)

$22.00

5 ml / Russia

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The main aspect of the mechanism of action of SkQ1 is protecting mitochondria from oxidative stress, which is a confirmed key factor in cell aging. That’s one of the reasons SkQ1 proved to be effective in a wide spectrum of models of age-related disorders. The main target of SkQ1 is to extend a healthspan.

The mechanism of action of SkQ1 involves at least two extremely complex and novel concepts: delivering a an extremely active antioxidant plastoquinone inside mitochondria and reducing reactive oxygen species production inside mitochondria in a controlled and sustainable manner.

Availability: in stock

 

Try also other SkQ1 revolutionary products: Exomitin^(®), MitoVitan^(®),MitoVitan Active^(®).

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