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Developed in the Soviet Union for the needs of the military, Bemitil (also known as Metaprot and AntiHot) has a long history of usage in clinical practice and in sport. It was developed in the 1970s and was successfully used during Afghanistan war, Chernobyl catastrophe and Olympic games in Moscow.

The drug has nootropic, regenerative, antihypoxic, antioxidant and immunomodulatory action.

The main purpose of Bemitil is increasing the physical and mental performance in people exposed to stressful conditions, and accelerating the recovery process after physical exertion. That makes it useful for athletes, especially for bodybuilders and runners. What is important is that Bemitil can be taken by healthy individuals.

But sport is not its only off-label usage. Bemitil works synergistically with other nootropics and can potentiate their effect, which makes this drug a possible part of a nootropic stack. According to clinical studies, the combination of Metaprot with the standard nootropic therapy is significantly more effective in the treatment of chronic fatigue, than a standard therapy alone.

Bemitil has quite a wide field of application in the clinical practice, too. In Russian medicine, this drug is used in the complex treatment of:

  • Asthenic conditions (chronic fatigue)
  • Traumatic brain injuries
  • Meningitis, encephalitis
  • Cerebrovascular and cognitive disorders

Mechanism of action

The chemical structure of Bemitil is similar to that of nucleobases adenine and guanine, which can explain its pharmacological effects.

Bemitil does increase the expression of RNA and proteins in the skeletal muscle, brain cells, liver, and kidneys. It also stimulates ATP formation and gluconeogenesis. Gluconeogenesis is the process of formation of glucose from non-carbohydrate substrates, such as lactate, fats and glucogenic amino acids, which plays an important role in the energy supply during exercise. Fasting, physical exercises and a low-carb diet rich in proteins and fats have also shown to stimulate gluconeogenesis.

Country of Manufacture: Belarus

Here you can read more Review and clinical trials of Metaprot