buy ipidacrine

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IPIDACRINE

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All statements on this page are for informational purposes only and have not been evaluated by the US FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Before using this product, consulting a qualified MD is mandatory. See more

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Buy Ipidacrine Online!

Ipidacrine is a reversible acetylcholinesterase inhibitor. It is used to improve memory and slow down memory impairment.
It is available to order in pill form at CosmicNootropic with worldwide delivery!

Chemical name Ipidacrine / Amiridine / NIK-247
Form: 50 pills of 20mg
Form description: White or off-white flat cylindrical tablets with a bevel
Active ingredient: Ipidacrine hydrochloride 20 mg
Excipients: Lactose monohydrate – 65 mg,
Potato starch – 14 mg,
Calcium stearate – 1 mg
СAS Number: 62732-44-9
ATC code: N06DA05
Shelf life: 5 years. Do not use it beyond the expiration date printed on the package.
Storage conditions: Store in a dry dark place at temperatures no higher than 25°C (77°F). Keep out of reach of children.
Terms of release: Requires prescription
Manufacturer: OlainFarm, Latvia

What is Ipidacrine?

Ipidacrine is a reversible cholinesterase inhibitor. The medication directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane K+ ion channels.

What Does Ipidacrine Do?

Ipidacrine has a direct stimulating effect on impulse conduction along nerve fibers and interneuronal and neuromuscular synapses of the peripheral and central nervous system. The pharmacological action of Ipidacrine is based on a combination of two mechanisms of action:

  • Blockade of potassium channels in the membrane of neurons and muscle cells;
  • Reversible inhibition of cholinesterase in synapses.

It is not only the acetylcholine effect on smooth muscles that is enhanced by Ipidacrine, but also adrenaline, serotonin, histamine, and oxytocin effects.

What are the Ipidacrine Benefits?

Ipidacrine has the following benefits for the body:

  • It improves and stimulates impulse conduction in the nervous system and neuromuscular transmission;
  • It enhances the contractility of smooth muscle organs under the influence of agonists of acetylcholine, adrenaline, serotonin, histamine, and oxytocin receptors, with the exception of potassium chloride;
  • It improves memory and inhibits memory impairment.

It is reported that Ipidacrine is of help in the treatment of Alzheimer’s disease [2] and other memory disorders, mono- and polyneuropathy, polyradiculopathy of various etiologies, myasthenia gravis, myasthenic syndrome, myasthenic crises, bulbar paralysis and paresis and intestinal atony.

Where to Order Ipidacrine Online?

You can order Ipidacrine online at CosmicNootropic. We offer Ipidacrine in packs of 50x20mg pills with worldwide shipping. We offer volume discounts!

You can order Ipidacrine and get it delivered to the USA, Europe, the UK, Asia, and many other regions and countries via CosmicNootropic.

 


Legal Disclaimer
This product has not been approved by the US FDA. All statements on this page are for informational purposes only and have not been evaluated by the US FDA.
This product is not intended to diagnose, treat, cure, or prevent any disease. See more

What is Ipidacrine Dosage, Administration?

Doses and duration of treatment with Ipidacrine are determined individually depending on the severity of the disease. A typical dosage is 10-20 mg 1-3 times a day, from 1 week to 6 months. The course of treatment can be repeated several times with a break between courses of 1-2 months.

What are the Side Effects of Ipidacrine?

According to the manufacturer, side effects are rare. They may include increased salivation and sweating, palpitation, nausea, diarrhea, jaundice, bradycardia, epigastric pain, increased secretion of bronchial secretions, bronchospasm, and convulsions.

There is a list of contraindications for use of Ipidacrine, please read the official instruction before administering this drug.

During the course of treatment avoid alcohol as it enhances the side effects of Ipidacrine.

Can Ipidacrine affect the ability to drive?

It is strongly recommended to refrain from driving vehicles and engaging in potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

  1. Burov et al (1991) [Experimental study of the effects of amiridin and tacrine on learning and memory] https://pubmed.ncbi.nlm.nih.gov/1893185/
  2. Kojima et al (1997) Effects of NIK-247 on cholinesterase and scopolamine-induced amnesia https://pubmed.ncbi.nlm.nih.gov/9228650/

  3. Kojima et al (2006) Ipidacrine (NIK‐247): A Review of Multiple Mechanisms as an Antidementia Agent https://www.researchgate.net/publication/227979788_Ipidacrine_NIK-247_A_Review_of_Multiple_Mechanisms_as_an_Antidementia_Agent

  4. Magomedova et al (2019) [An outpatient with hand numbness: old prejudices, new strategies of differential diagnosis and treatment] https://pubmed.ncbi.nlm.nih.gov/31089090/

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