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neurobion-instruction

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NEUROBION ® (Vitamins B1, B6, B12)

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Neurobion is a complex of group B vitamins – Vitamin B1, Vitamin B6, and Vitamin B12. These are water-soluble vitamins that play an important part in the neurological processes of the CNS (Central Nervous System).

The information about dose, administration, and ingredients can be found on the packaging.

Neurobion comes in 2 forms: pills and injections.

 

Produced by Merck, Austria / Dr. Reddy’s Laboratories, India.

 

Check out other products from the Anti-Aging & Regeneration category!

Contents

Pills

Active ingredients: thiamin disulfide (vitamin B1) 100 mg, pyridoxine hydrochloride (vitamin B6) 200 mg, cyanocobalamin (vitamin B12) 200 mcg.

Injections

Active ingredients: thiamin disulfide (vitamin B1) 100 mg, pyridoxine hydrochloride (vitamin B6) 200 mg, cyanocobalamin (vitamin B12) 1 mg.

Manufacturer

Merck, Austria / Dr. Reddy's Laboratories, India.
Additional information about dosage, administration, and ingredients can be found on the packaging.
  1. Fu et al (1988) B vitamins suppress spinal dorsal horn nociceptive neurons in the cat https://www.ncbi.nlm.nih.gov/pubmed/3226608
  2. D Bonke, B Nickel (1989) Improvement of fine motoric movement control by elevated dosages of vitamin B1, B6, and B12 in target shooting https://www.ncbi.nlm.nih.gov/pubmed/2507698
  3. Dakshinamurti et al (1990) Influence of B vitamins on binding properties of serotonin receptors in the CNS of rats https://www.ncbi.nlm.nih.gov/pubmed/2157087
  4. Jurna et al (1990) Acute effects of vitamin B6 and fixed combinations of vitamin B1, B6 and B12 on nociceptive activity evoked in the rat thalamus: dose-response relationship and combinations with morphine and paracetamol https://www.ncbi.nlm.nih.gov/pubmed/2157085
  5. Magana-Villa (2013) B-vitamin mixture improves the analgesic effect of diclofenac in patients with osteoarthritis: a double blind study https://www.ncbi.nlm.nih.gov/pubmed/23526240
  6. Syed et al (2013) Vitamin B12 Supplementation in Treating Major Depressive Disorder: A Randomized Controlled Trial https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856388/
  7. L Shen et al (2015) Associations between B Vitamins and Parkinson’s Disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586528/
  8. Dong et al (2015) Efficacy of Supplementation with B Vitamins for Stroke Prevention: A Network Meta-Analysis of Randomized Controlled Trials https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565665/
  9. Kamchatnov et al (2015) The use of neurobion in neurological practice https://www.ncbi.nlm.nih.gov/pubmed/26525818
  10. B Jayabalan, L Low (2016) Vitamin B supplementation for diabetic peripheral neuropathy https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759374/
  11. Rathod et al (2016) Novel insights into the effect of vitamin B12 and omega-3 fatty acids on brain function https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727338/
  12. Ebrahimi et al (2018) Effect of vitamins B1, B6, and B12 (Neurobion) on Diisopropylfluorophosphate–induced Delayed Neuropathy in Mice https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094411/
  13. Togha et al (2020) Suppression of Menstrual-Related Migraine Attack Severity Using Pyridoxine, Thiamine, and Cyanocobalamin: A Quasi-Experimental Within-Subject Design https://www.researchgate.net/publication/341831464 
  14. S Baltrusch (2021) The Role of Neurotropic B Vitamins in Nerve Regeneration https://pubmed.ncbi.nlm.nih.gov/34337067/
  15. H Nguyen, M-S Kim (2022) The role of mixed B vitamin intakes on cognitive performance: Modeling, genes and miRNAs involved https://pubmed.ncbi.nlm.nih.gov/35714552/
  16. Paez-Hurtado et al (2023) Mechanisms of action of vitamin B1 (thiamine), B6 (pyridoxine), and B12 (cobalamin) in pain: a narrative review https://pubmed.ncbi.nlm.nih.gov/35156556/

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