buy cavinton Vinpocetine

AUTHENTIC PRODUCTS

Only original pharmaceutical products that passed 3 stages of clinical trials.

GMP QUALITY

Our products are produced on GMP or state licensed factories.

10% CRYPTO DISCOUNT

10% discount for paying in BTC or other cryptocurrency.

PAYMENT BY CARD

Convenient Payment by Visa or MasterCard.

GUARANTEED DELIVERY

Guaranteed delivery times and clear Reshipment & Refund Rules.

PROMPT SHIPPING

Different shipping methods and same or next day shipping.

VINPOCETINE (Cavinton ®)

3 Reviews

Legal Disclaimer

All statements on this page are for informational purposes only and have not been evaluated by the US FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Before using this product, consulting a qualified MD is mandatory. See more

Buy more, get it as low as

2
$6.65
Save 5%
3
$6.51
Save 7%
4
$6.37
Save 9%
5
$6.23
Save 11%
6
$6.16
Save 12%
7
$6.09
Save 13%
8
$6.02
Save 14%
9 +
$5.95
Save 15%
Show More

Buy Vinpocetine (Cavinton ®) Online!

Vinpocetine (Cavinton ®) is a nootropic of plant origin. It improves blood flow to the brain and is used to treat cerebrovascular disorders such as strokes and atherosclerosis. The vasodilatory action of Vinpocetine is mediated by smooth muscle relaxation and a decrease in blood viscosity.

📦 Save with the volume discount 📦

Synonyms Ethyl apovincaminate
Form: 50 pills of 5mg
Form description: Flat, round, chamfered, odorless tablets of white or off-white color with “CAVINTON” engraved on one side.
Active ingredient: Vinpocetine – 5 mg
Excipients: Colloidal silicon dioxide, magnesium stearate, talc, corn starch, lactose monohydrate.
СAS Number: 42971-09-5
ATC code: N06BX18
Pharmacological action: Psychostimulant and nootropic agent
Shelf life: 5 years. Do not use it beyond the expiration date printed on the package.
Storage conditions: Store in a dry dark place at temperatures no higher than 30°C (86°F). Keep out of reach of children.
Terms of release: Over-the-counter
Manufacturer: Gedeon Richter, Hungary https://www.gedeonrichter.com/

What is Vinpocetine?

Vinpocetine (ethyl apovincaminate) is a nootropic drug obtained from vincamine, an alkaloid of the Vinca minor plant. Vinpocetine was discovered in the 1960s in Hungary and it has a history of medicinal use since 1978. Currently, it is known under the brand name Cavinton, which is a #2 bestselling drug of one of the largest European pharmaceutical companies, Gedeon Richter.

Besides wide usage in medicine, ethyl apovincaminate is often seen in nootropic supplements stacks available on the US market. It is also a component of a combination drug Vinpotropile, widely used in Russia.

What is the Mechanism of Action of Vinpocetine (Cavinton)?

The mechanism of action of vinpocetine consists of several elements: it improves cerebral blood flow and brain metabolism and has a beneficial effect on the rheological properties of blood.

The neuroprotective effect is realized by reducing the adverse cytotoxic effect of excitatory amino acids. It blocks voltage-dependent Na+ and Ca2+ channels and NMDA- and AMPA-receptors. It can increase the neuroprotective effect of adenosine.

Vinpocetine stimulates brain metabolism: it increases the uptake and consumption of glucose and oxygen and improves tolerance to hypoxia. Vinpocetine shifts glucose metabolism towards the energetically more favorable aerobic pathway.

Vinpocetine enhances the metabolism of serotonin and norepinephrine in the brain, stimulates the noradrenergic neurotransmitter system, and has an antioxidant effect. As a result, vinpocetine might have a cerebroprotective effect.

Vinpocetine is said to improve microcirculation in the brain by inhibiting platelet aggregation by reducing pathologically increased blood viscosity. It can also promote the passage of oxygen into cells.

What are the Benefits and Side Effects of Vinpocetine (Cavinton)?

Vinpocetine is a cerebral vasodilator, thus its primary pharmacological effect is the improvement of cerebral blood flow. The vasodilatory action of Vinpocetine is mediated by smooth muscle relaxation and a decrease in blood viscosity.

Besides the beneficial effect on blood flow, Vinpocetine was shown to have pronounced nootropic and neuroprotective benefits.

Vinpocetine inhibits voltage-gated sodium channels with a blocking potency comparable to that of Phenytoin, an anticonvulsant drug.

What is Vinpocetine Used For?

  • Its primary clinical use is the treatment of cerebrovascular disorders such as strokes, dementia, and atherosclerosis;
  • Vinpocetine can help enhance memory and cognition;
  • It is used to improve cognitive function in those with age-related cognitive decline;
  • According to clinical trials and anecdotal experiences, you can use Vinpocetine to relieve tinnitus. This also applies to another cerebral vasodilator of herbal origin, Bilobil (Ginkgo Biloba extract). It is also suggested that Cavinton (Vinpocetine) has only minor side effects.

Where Can I Order Vinpocetine Online?

You can buy Vinpocetine online from different vendors. CosmicNootropic offers Vinpocetine (Cavinton) in packs of 50x5mg pills. We offer worldwide shipping with volume discounts! Always be sure to do your research before purchasing any nootropic supplement to ensure you are getting a quality product.

You can order Vinpocetine and get it delivered to the USA, Europe, the UK, Asia, and many other regions and countries via CosmicNootropic.

 


Legal Disclaimer
This product has not been approved by the US FDA. All statements on this page are for informational purposes only and have not been evaluated by the US FDA.
This product is not intended to diagnose, treat, cure, or prevent any disease. See more

What is Cavinton Dosage and Administration?

The recommended dose is 5–10 mg (1-2 tablets) 2-3 times per day. The course duration is 3–8 weeks. Before discontinuing taper the dose down.

It is possible to have 2-3 courses over 1 year period.

What are the Side Effects of Vinpocetine (Cavinton)?

Vinpocetine is usually well-tolerated and side effects are unlikely to occur. However, they may include:

  • Labile/low blood pressure;
  • Tachycardia;
  • Extrasystole;
  • Sleepiness/insomnia;
  • Vertigo;
  • Drowsiness;
  • Sweating;
  • Dry mouth;
  • Nausea;
  • Heartburn;
  • Allergic reactions.

Contraindications

  • Hypersensitivity;
  • The acute phase of hemorrhagic stroke;
  • Ischemic heart disease or acute arrhythmia;
  • Pregnancy and lactation;
  • Lactose intolerance;
  • Age below 18 years.

Drug interaction

Vinpocetine does not interact with beta-blockers (Cloranolol, Pindolol), Clopamide, Glibenclamide, Digoxin, Acenocoumarol, Hydrochlorothiazide, and Imipramine. The drug potentiates the hypotensive effect of Methyldopa.

Despite the lack of data regarding interactions with drugs that have central, antiarrhythmic, and anticoagulant actions, Vinpocetine should be used cautiously if coadministered with them.

  1. Dutov et al (1986) Use of cavinton in epilepsy https://www.ncbi.nlm.nih.gov/pubmed/3751419
  2. Burtsev et al (1988) Effectiveness of using cavinton in patients of different ages with chronic forms of cerebrovascular diseases (clinico-rheographic research) https://www.ncbi.nlm.nih.gov/pubmed/3364094
  3. B Kiss, E Karpati (1996) Mechanism of action of vinpocetine https://www.ncbi.nlm.nih.gov/pubmed/9082841
  4. Szakall et al (1998) Cerebral effects of a single dose of intravenous vinpocetine in chronic stroke patients: a PET study https://www.ncbi.nlm.nih.gov/pubmed/9780850
  5. S Szatmari, P Whitehouse (2003) Vinpocetine for cognitive impairment and dementia https://www.ncbi.nlm.nih.gov/pubmed/12535455
  6. Protasov et al (2006) Cavinton forte treatment of cerebral vascular insufficiency in patients with coronary heart disease and arterial hypertension https://www.ncbi.nlm.nih.gov/pubmed/16921716
  7. Nyakas et al (2009) Neuroprotective effects of vinpocetine and its major metabolite cis-apovincaminic acid on NMDA-induced neurotoxicity in a rat entorhinal cortex lesion model https://www.ncbi.nlm.nih.gov/pubmed/19492990
  8. Afon’kin et al (2009) The new scheme of cavinton application to the treatment of chronic neurosensory loss of hearing https://www.ncbi.nlm.nih.gov/pubmed/20081798
  9. E Chukanova (2010) Efficacy of cavinton in the treatment of patients with chronic blood flow insufficiency. Russian multicenter clinical-epidemiological program “CALIPSO” https://www.ncbi.nlm.nih.gov/pubmed/21311488
  10. Jeon et al (2010) Vinpocetine inhibits NF-κB–dependent inflammation via an IKK-dependent but PDE-independent mechanism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906898/
  11. Patyar et al (2011) Role of vinpocetine in cerebrovascular diseases https://www.ncbi.nlm.nih.gov/pubmed/21857073
  12. Cai et al (2013) Vinpocetine Attenuates Lipid Accumulation and Atherosclerosis Formation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682500/
  13. A Ogunrin (2014) Effect of Vinpocetine (Cognitol™) on Cognitive Performances of a Nigerian Population https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160700/
  14. Alkuraishy et al (2014) Vinpocetine and Pyritinol: A New Model for Blood Rheological Modulation in Cerebrovascular Disorders—A Randomized Controlled Clinical Study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274818/
  15. Ruiz-Miyazawa et al (2015) Vinpocetine Reduces Carrageenan-Induced Inflammatory Hyperalgesia in Mice by Inhibiting Oxidative Stress, Cytokine Production and NF-κB Activation in the Paw and Spinal Cord
  16. Manda et al (2015) Studies on Pharmacokinetic Drug Interaction Potential of Vinpocetine https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533163/
  17. Lee et al (2015) Vinpocetine Inhibits Streptococcus pneumoniae–Induced Upregulation of Mucin MUC5AC Expression via Induction of MKP-1 Phosphatase in the Pathogenesis of Otitis Media https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456630/
  18. Wu et al (2017) Vinpocetine Attenuates Pathological Cardiac Remodeling by Inhibiting Cardiac Hypertrophy and Fibrosis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663637/
  19. Zhang et al (2018) An update on Vinpocetine: New discoveries and clinical implications https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766389/
  20. Liu et al (2019) Vinpocetine in the treatment of poststroke cognitive dysfunction: A protocol for systematic review and meta-analysis https://pubmed.ncbi.nlm.nih.gov/30732122/ 
  21. Al-Kuraishy et al  (2022) Vinpocetine is the forthcoming adjuvant agent in the management of COVID-19 https://pubmed.ncbi.nlm.nih.gov/35662743/ 
  22. Khalil et al (2022) Vinpocetine (A comprehensive profile) https://pubmed.ncbi.nlm.nih.gov/35396012/
  23. Hu et al (2022) Vinpocetine and coenzyme Q10 combination alleviates cognitive impairment caused by ionizing radiation by improving mitophagy https://pubmed.ncbi.nlm.nih.gov/35907514/

5

Based on 3 Reviews

(3)

(0)

(0)

(0)

(0)

 

05/03/2024

Sergii

Sergii

 Verified Buyer
GB

GB

Good stuff )

Combined with Noopept and Nanotropil (Phenylpiracetam), works great! Also, great customer support, genuine items, and fast delivery.

05/06/2024

Dear Sergii, thank you for your kind words! We are happy to hear that you are satisfied with the product and fast delivery :)

Was this helpful?

0

09/19/2021

Aigan

Aigan

 Verified Buyer
GB

GB

Excellent

Noticably Better than vinpocetine powder or capsules I had been using. Smaller dosage now needed. Very happy with cavinton

Was this helpful?

0

05/06/2019

A

Aniabl

 Verified Buyer

Amazing product !!!

Help in an incredible way with mental acuity and memory. It helps me a lot!

Was this helpful?

0
< 1 >

19 days ago

Review

Sergii Verified Buyer

Good stuff )

Combined with Noopept and Nanotropil (Phenylpiracetam), works great! Also, great customer support, genuine items, and fast delivery.

Reply:

Dear Sergii, thank you for your kind words! We are happy to hear that you are satisfied with the product and fast delivery :)

Response
addition slider

Thank you!

You will now receive regular updates from us!