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VINPOCETINE (Cavinton ®)
3 Reviews
Buy Vinpocetine Online!
Vinpocetine (Cavinton ®) is a nootropic of plant origin that can improve blood flow to the brain. It is used in symptoms of cerebrovascular disorders such as strokes and atherosclerosis. The vasodilatory action of Vinpocetine is mediated by smooth muscle relaxation and a decrease in blood viscosity.
| Synonyms | Ethyl apovincaminate |
| Form: | 50 pills of 5mg |
| Form description: | Flat, round, chamfered, odorless tablets of white or off-white color with “CAVINTON” engraved on one side. |
| Active ingredient: | Vinpocetine – 5 mg |
| Excipients: | Colloidal silicon dioxide, magnesium stearate, talc, corn starch, lactose monohydrate. |
| СAS Number: | 42971-09-5 |
| ATC code: | N06BX18 |
| Pharmacological action: | Psychostimulant and nootropic agent |
| Shelf life: | 5 years. Do not use it beyond the expiration date printed on the package. |
| Storage conditions: | Store in a dry dark place at temperatures no higher than 30°C (86°F). Keep out of reach of children. |
| Terms of release: | Over-the-counter |
| Manufacturer: | Gedeon Richter, Hungary https://www.gedeonrichter.com/ |
What is Vinpocetine?
Vinpocetine (ethyl apovincaminate) is a nootropic drug obtained from vincamine, an alkaloid of the Vinca minor plant. Vinpocetine was discovered in the 1960s in Hungary and has a history of practical use since 1978. Currently, it is known under the brand name Cavinton, which is one of the bestselling compounds of Gedeon Richter, a large European pharmaceutical company.
Besides, ethyl apovincaminate, the active component of Cavinton, is often seen in nootropic supplements stacks available on the US market. It is also a component of the combination drug Vinpotropile, widely used in Russia for its nootropics effects.
What is Vinpocetine Used For?
Its primary studies include the treatment of cerebrovascular disorders such as strokes, dementia, and atherosclerosis. [1] Vinpocetine can help enhance memory and cognition, including in people with age-related cognitive decline.
According to clinical trials and anecdotal experiences, Vinpocetine can relieve tinnitus. [2]
What are Vinpocetine Benefits and Effects?
Vinpocetine is a cerebral vasodilator, meaning its primary pharmacological effect is the improvement of cerebral blood flow. [3] The vasodilatory action of Vinpocetine is mediated by smooth muscle relaxation and a decrease in blood viscosity. Besides, Vinpocetine was shown to have pronounced nootropic and neuroprotective benefits. [4]
Is Vinpocetine Safe To Take?
Vinpocetine is usually well-tolerated and side effects are rare. However, they may include:
- Labile/low blood pressure;
- Tachycardia;
- Extrasystole;
- Sleepiness/insomnia;
- Vertigo;
- Drowsiness;
- Sweating;
- Dry mouth;
- Nausea;
- Heartburn;
- Allergic reactions.
There are also contraindications to the use of Cavinton, namely:
- Hypersensitivity;
- The acute phase of hemorrhagic stroke;
- Ischemic heart disease or acute arrhythmia;
- Pregnancy and lactation;
- Lactose intolerance;
- Age below 18 years.
What is Vinpocetine Dosage?
The recommended dose by the manufacturer is 5–10 mg (1-2 tablets) 2-3 times per day. The course duration is 3–8 weeks. Before discontinuing tapering the dose down is recommended.
FAQ:
What Is Vinpocetine Drug Interaction?
According to the manufacturer, Vinpocetine does not interact with beta-blockers (Cloranolol, Pindolol), Clopamide, Glibenclamide, Digoxin, Acenocoumarol, Hydrochlorothiazide, and Imipramine. The compound potentiates the hypotensive effect of Methyldopa. Vinpocetine shall be used cautiously if coadministered with drugs that have central, antiarrhythmic, and anticoagulant actions, because of the lack of data regarding such interactions.
What is the Mechanism of Action of Vinpocetine (Cavinton)?
The mechanism of action of Vinpocetine consists of several elements: improvement of cerebral blood flow and brain metabolism and beneficial effect on rheological properties of blood.
The product is not used for cure, mitigation, treatment, or prevention of any disease. Always consult a healthcare professional before using this product to determine if it is appropriate for you. For informational purposes, you may also refer to the official instructions provided by the manufacturer.
- Dutov et al (1986) Use of cavinton in epilepsy https://www.ncbi.nlm.nih.gov/pubmed/3751419
- Burtsev et al (1988) Effectiveness of using cavinton in patients of different ages with chronic forms of cerebrovascular diseases (clinico-rheographic research) https://www.ncbi.nlm.nih.gov/pubmed/3364094
- B Kiss, E Karpati (1996) Mechanism of action of vinpocetine https://www.ncbi.nlm.nih.gov/pubmed/9082841
- Szakall et al (1998) Cerebral effects of a single dose of intravenous vinpocetine in chronic stroke patients: a PET study https://www.ncbi.nlm.nih.gov/pubmed/9780850
- S Szatmari, P Whitehouse (2003) Vinpocetine for cognitive impairment and dementia https://www.ncbi.nlm.nih.gov/pubmed/12535455
- Protasov et al (2006) Cavinton forte treatment of cerebral vascular insufficiency in patients with coronary heart disease and arterial hypertension https://www.ncbi.nlm.nih.gov/pubmed/16921716
- Nyakas et al (2009) Neuroprotective effects of vinpocetine and its major metabolite cis-apovincaminic acid on NMDA-induced neurotoxicity in a rat entorhinal cortex lesion model https://www.ncbi.nlm.nih.gov/pubmed/19492990
- Afon’kin et al (2009) The new scheme of cavinton application to the treatment of chronic neurosensory loss of hearing https://www.ncbi.nlm.nih.gov/pubmed/20081798
- E Chukanova (2010) Efficacy of cavinton in the treatment of patients with chronic blood flow insufficiency. Russian multicenter clinical-epidemiological program “CALIPSO” https://www.ncbi.nlm.nih.gov/pubmed/21311488
- Jeon et al (2010) Vinpocetine inhibits NF-κB–dependent inflammation via an IKK-dependent but PDE-independent mechanism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906898/
- Patyar et al (2011) Role of vinpocetine in cerebrovascular diseases https://www.ncbi.nlm.nih.gov/pubmed/21857073
- Cai et al (2013) Vinpocetine Attenuates Lipid Accumulation and Atherosclerosis Formation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682500/
- A Ogunrin (2014) Effect of Vinpocetine (Cognitol™) on Cognitive Performances of a Nigerian Population https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160700/
- Alkuraishy et al (2014) Vinpocetine and Pyritinol: A New Model for Blood Rheological Modulation in Cerebrovascular Disorders—A Randomized Controlled Clinical Study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274818/
- Manda et al (2015) Studies on Pharmacokinetic Drug Interaction Potential of Vinpocetine https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533163/
- Lee et al (2015) Vinpocetine Inhibits Streptococcus pneumoniae–Induced Upregulation of Mucin MUC5AC Expression via Induction of MKP-1 Phosphatase in the Pathogenesis of Otitis Media https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456630/
- Wu et al (2017) Vinpocetine Attenuates Pathological Cardiac Remodeling by Inhibiting Cardiac Hypertrophy and Fibrosis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663637/
- Zhang et al (2018) An update on Vinpocetine: New discoveries and clinical implications https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766389/
- Liu et al (2019) Vinpocetine in the treatment of poststroke cognitive dysfunction: A protocol for systematic review and meta-analysis https://pubmed.ncbi.nlm.nih.gov/30732122/
- Al-Kuraishy et al (2022) Vinpocetine is the forthcoming adjuvant agent in the management of COVID-19 https://pubmed.ncbi.nlm.nih.gov/35662743/
- Khalil et al (2022) Vinpocetine (A comprehensive profile) https://pubmed.ncbi.nlm.nih.gov/35396012/
- Hu et al (2022) Vinpocetine and coenzyme Q10 combination alleviates cognitive impairment caused by ionizing radiation by improving mitophagy https://pubmed.ncbi.nlm.nih.gov/35907514/
5
Based on 3 Reviews
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08/28/2025
Vinchinou
Verified BuyerUS
Review vinpocetin
Mechanistically, Vinpocetine is intriguing. It inhibits voltage-dependent sodium channels and modulates calcium influx, which can reduce excitotoxicity. Clinically, it has shown modest benefit in ischemic stroke and age-related cognitive decline. In healthy individuals, the cognitive enhancement claims are overstated, though some anecdotal reports suggest subtle benefits. More robust, double-blind trials are needed for conclusive efficacy data in nootropic use.
08/28/2025
CosmicNootropic
Hi there! Thank you for such an insightful and detailed review of Vinpocetine. We really appreciate the depth of knowledge you’ve shared, it’s valuable for others who are considering the product.
08/18/2025
J
Verified BuyerJP
VINPOCETINE Cavinton
took Cavinton to help with mental clarity during exam prep. I feel like I can study longer and retain more info. It\'s subtle but noticeable.
08/18/2025
CosmicNootropic
That’s great to hear, Jeffrey! Vinpocetine is known for supporting cerebral blood flow, which can help with focus and memory retention — perfect for study sessions. We’re glad it gave you that extra mental edge during exam prep!
05/03/2024
Sergii
Verified BuyerGB
Good stuff )
Combined with Noopept and Nanotropil (Phenylpiracetam), works great! Also, great customer support, genuine items, and fast delivery.
05/06/2024
CosmicNootropic
Dear Sergii, thank you for your kind words! We are happy to hear that you are satisfied with the product and fast delivery :)
09/19/2021
Aigan
Verified BuyerGB
Excellent
Noticably Better than vinpocetine powder or capsules I had been using. Smaller dosage now needed. Very happy with cavinton
05/06/2019
Aniabl
Verified BuyerAmazing product !!!
Help in an incredible way with mental acuity and memory. It helps me a lot!
