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Adaptogens are supplements that are used to increase the body’s resistance to adverse conditions and to strengthen immunity. They are popular among people who are looking to boost sports performance, increase endurance, and enhance the body’s resistance to various damaging factors such as shock, hypoxia, and extreme temperatures.

What is inside the Adaptogens Bundle?

Adaptogens Bundle contains samples of five bestsellers that we have hand picked for you based on their effectiveness and safety.

Product Name Amount of the
active substance
Number of Pills
      in the Bundle 

Mildronate [Meldonium] 500 mg 10 pills Grindex
    Bemitil / Bemiton      250 mg 10 pills IGIC NAS of Belarus
Adaptol [Mebicar] 300 mg 10 pills TatChemPharmPreparaty
Hypoxen 250 mg 10 pills Olifen
Mexidol 125 mg 10 pills Pharmasoft

How to take Adaptogens Bundle?

The optimal way to take adaptogens in the bundle is in sequence, with 2-3 week intervals. In this manner, you can track the effects and pick out an adaptogen or a stack that works best for you.

Product Name Dosage
(Pills Per Day)
Days of Use

Mildronate [Meldonium] 1-2 pills 5-10 days
    Bemitil / Bemiton      2-4 pills 2-5 days
Adaptol [Mebicar] 2-6 pills 2-5 days
Hypoxen 2-5 pills 2-5 days
Mexidol 2-4 pills 2-5 days

Why shall I buy Adaptogens bundle?

This product is for those who like to try popular membrane protectors, performance boosters, and anti-hypoxic medications or who look for the perfect adaptogenic stack. Since every person is unique, you can learn which product is right for you only after sampling it. Take a serious approach to your well-being and health, try out this Adaptogens Bundle.

What are the benefits of Adaptogens Bundle?

  • First of all, the supplements in the Bundle have been extensively studied and used in post-Soviet countries and each of them has dozens of papers on Pubmed.
  • Secondly, they are produced officially by reputable manufacturers in compliance with local and international requirements.
  • Thirdly, this adaptogens sample pack is money-saving as you get 5 bestsellers at 1/3 of the price you would spend if you bought them separately.

Why do healthy people take Adaptogens?

Healthy individuals may find Adaptogens useful if they need to run sustainable energy levels without major dips. Coffee, cigarettes and other stimulants can put much stress on the nervous system and their effect is short-lived. The products in the Adaptogenic bundle have a different, more profound mechanism of action. They are not stimulants in the conventional sense. Adaptogens are intended to be used in a course, during and after which the energy is restored to the normal level.

Also, check out nootropics and anxiolytics bundles.

What is included in the Adaptogens Bundle?

1. Mildronate (10 capsules)

Active ingredient: meldonium dihydrate — 500 mg. 

Excipients: potato starch, colloidal silicon dioxide, calcium stearate, titanium dioxide (E 171), and gelatin.

Instructions: Orally, before 5 pm. The duration and intensity of the course are determined individually. An average daily dose is 1-2 pills. Capsules can be taken together or separately. 


2. Bemitil / Bemiton (10 capsules)

Active ingredient: ethylthiobenzimidazole hydrobromide — 250 mg.

Excipients: hydroxypropyl cellulose, anhydrous colloidal silicon dioxide, magnesium stearate, lactose monohydrate. 

Instructions: Orally, after meals. The usual course duration is 5 days followed by a break. An average daily dose is 1-2 pills. 


3. Mebicar (10 pills)

Active ingredient: Temgicoluril — 300 mg. 

Excipients: povidone — 1.5 mg, calcium stearate — 1.5 mg. 

Instructions: Orally, regardless of food intake. The average dose is 1-4 pills 2-3 times a day. The maximum single dose is 3 g, the maximum daily dose is 10 g. 


4. Hypoxen (10 capsules)

Active ingredient: sodium polydihydroxyphenylene thiosulfonate (hypoxene) — 250 mg. 

Excipients: gelatin, black iron oxide (E172), red iron oxide (E172), yellow iron oxide (E172), titanium dioxide (E171).

Instructions: Orally, before or during meals, with a small amount of liquid. An average daily dose is 2–4 capsules. The maximum daily dose is 12 capsules. 

Warning: Do not use it if you are under 18 y.o., pregnant or breastfeeding, or if you have any known or suspected medical conditions. In case of any allergic reactions, Hypoxen shall be discontinued.


5. Mexidol (10 pills)

Active ingredient: ethylmethylhydroxypyridine succinate — 125 mg. 

Excipients: lactose monohydrate — 97.5 mg; povidone — 25 mg; magnesium stearate — 2.5 mg. 

Instructions: Orally, regardless of food intake. The duration of the course is determined individually. The average dose is 1-2 pills 3 times a day; the maximum daily dose is 800 mg. 


Storage Conditions

At a temperature not higher than 25°C (77°F) in a dry dark place. Keep out of reach of children.


Do not use it if you are under 18 y.o., pregnant or breastfeeding, or if you have any known or suspected medical conditions. In case of any allergic reactions or high blood pressure, the supplement shall be discontinued.

Research behind the Adaptogens Bundle

All supplements in the bundle are well-studied. You can find many research papers on each of them. We highlighted a few below. More links are available on the product pages.


Mildronate [Meldonium] 

  1. Klusa et al (2013) Mildronate and its Neuroregulatory Mechanisms: Targeting the Mitochondria, Neuroinflammation, and Protein Expression
  2. Schobersberger et al (2016) Story behind meldonium-from pharmacology to performance enhancement: a narrative review
  3. Gureev et al (2021) Mildronate protects heart mtDNA from oxidative stress toxicity induced by exhaustive physical exercise
  4. Savic et al (2021) Hyperpolarized magnetic resonance shows that the anti-ischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved post-ischemic function in the diabetic heart

Bemitil / Bemiton 

  1. Kibalchich et al (2011) Pharmacokinetics of domestic actoprotector drug Metaprot in healthy volunteers
  2. V Yasnetsov et al (2016) Studying some pharmacological effects of new 3-hydroxypyridine derivative
  3. Kwiatkowska et al (2018) Detection of bemitil and its metabolite in urine by means of LC-MS/MS in view of doping control analysis

Adaptol [Mebicar]

  1. V Vorob’eva, V Repina (2016) An open comparative observational study of the efficacy and safety of adaptol in anxiety-asthenic disorders in patients with chronic cerebral ischemia
  2. J Zhitkova, D Hasanova (2017) An experience of using mebicar in patients with autonomic dysfunction associated with anxiety disorder
  3. Kotova et al (2022) [Sleep disorders in post-COVID syndrome – a problem of psychiatry or neurology?]


  1. Kosenko et al (2010) The drug hypoxen: A new inhibitor of mitochondrial respiration and dehydrogenases
  2. Murzaeva et al (2010) Effect of hypoxenum on bioenergetic processes in mitochondria and the activity of ATP-sensitive potassium channel
  3. Dugieva et al (2012) Impact of hypoxen therapy on postoperative course in gynecologic patients
  4. L Khnychenko, I Okunevich (2015) Experimental assessment of inflammatory effect of hypoxen


  1. Androfagina et al (2015) Mexidol in the rehabilitation of patients in the acute ischemic stroke
  2. Gromova et al (2018) Experience with mexidol in neurological practice
  3. Shamrey et al (2020) [Possibilities of using Mexidol in the complex therapy of mental disorders]
  4. Voronina et al (2022) [The role of oxidative stress in hemorrhagic stroke and restorative effects of Mexidol]


Based on 1 Reviews










 Verified Buyer


Awesome products and company!!

I\'ll just give a review on all of them separately. The order came very fast (express shipping though) and the customer service was great btw. Bemitil - was a weird one, it didn\'t really give me a huge energy boost when I took it however I felt a lot more resistant to stress and I felt very calm if anything. My performance in the gym or in sprints did not improve. However my recovery did, I noticed that my one calf muscle that was very strained healed about 3 days in. I would get a random boost of energy around 5pm and it would go away in an hour and I\'d sleep like a baby, at some points in the day I even felt too calm. I also can no longer drink coffee still, it amplifies all of its effects (dopamine, stimulation, energy, anxiety) and seemed to last all the way until bedtime. I got lots of stuff done though! Mildronate - was awesome, this has to be my favorite, the edge in performance with jogging, sprinting, recovery between sets and gym performance was obvious. It was all mostly due to a boost in endurance, I could just keep going through workouts where I\'d normally be exhausted. Also I think due to the brain using more oxygen and glucose, my brain felt crystal clear, I could focus very easily. Literally no side effects for me, just felt like a God. Also it worked extremely well with Rhodiola and Panax Ginseng. Hypoxen - has to be my second favorite, also had a very obvious boost in endurance, the longer the sprint or jog the better it helped, it was like Coenzyme Q10 on crack. I\'d feel the ATP boost a bit more than Mildronate, the best way to say it is it felt like more of a body high Mildronate was body and mind as well as I feel like Mildronate increased power output more. Hypoxen went nicely with coffee (before I tried Bemitil lol). Adaptol - was really nice, I could compare it to a high dose of Theanine, and when you add herbal tranquilizers like passionflower, hops, valerian, my favorite was lemon balm, it would put you straight to bed, kind of similar to a Cannabis feeling of relaxation. It makes an awesome recovery tool after physical and mental stress especially. My friend also liked it for social anxiety, a nice bonus. Finally Mexidol - it was really calming and felt like it was cooling down my brain, it gave me really good tunnel vision for work, I felt less stressed and it seemed to help sleep. it also blended well with coffee, it brought down the stimulation and increased my mood with it. Man I miss that ****. Thanks Cosmic Nootropic!


Dear Jared, Thank you for taking the time to provide such a detailed and insightful review of the products you've tried from CosmicNootropic. We're delighted to hear about your positive experiences and the benefits you've noticed. Your detailed descriptions and comparisons will undoubtedly help others considering these products. We really appreciate your trust!

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